ID J4K7J0_9FIRM Unreviewed; 419 AA.
AC J4K7J0;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=PDZ/DHR/GLGF domain protein {ECO:0000313|EMBL:EJP19356.1};
GN ORFNames=HMPREF1140_0562 {ECO:0000313|EMBL:EJP19356.1};
OS Lachnoanaerobaculum sp. ICM7.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Lachnoanaerobaculum.
OX NCBI_TaxID=936594 {ECO:0000313|EMBL:EJP19356.1, ECO:0000313|Proteomes:UP000006599};
RN [1] {ECO:0000313|EMBL:EJP19356.1, ECO:0000313|Proteomes:UP000006599}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ICM7 {ECO:0000313|EMBL:EJP19356.1,
RC ECO:0000313|Proteomes:UP000006599};
RA Durkin A.S., McCorrison J., Torralba M., Gillis M., Methe B., Sutton G.,
RA Nelson K.E.;
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S1C family.
CC {ECO:0000256|ARBA:ARBA00010541}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJP19356.1}.
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DR EMBL; ALJL01000030; EJP19356.1; -; Genomic_DNA.
DR RefSeq; WP_009663859.1; NZ_ALJL01000030.1.
DR AlphaFoldDB; J4K7J0; -.
DR PATRIC; fig|936594.3.peg.2153; -.
DR Proteomes; UP000006599; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00987; PDZ_serine_protease; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001940; Peptidase_S1C.
DR PANTHER; PTHR22939; SERINE PROTEASE FAMILY S1C HTRA-RELATED; 1.
DR PANTHER; PTHR22939:SF129; SERINE PROTEASE HTRA2, MITOCHONDRIAL; 1.
DR Pfam; PF13180; PDZ_2; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 35..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 310..379
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
SQ SEQUENCE 419 AA; 45115 MW; FF4D8952439097FF CRC64;
MPNTKKEHEP DEKNPFIKQT IIEDKKARNK KAVSAACLAI VFGMVAGPSM ALTSHIINKN
ILSKKTKTTI EIPKEETTVE SSEEAESSEQ VEDIVASAIE SIDLNEKNLV QMYESLSKVA
EKKDNTIVKI SAVTTDTDWF NNTLQNESSC SGIIIAKSGD SLIVLAPNME KESGIKVAFF
DGSNQEATVI GSDGLTNLMI LSVDTSSMEE KIKNIEPVVL GNSYQLKKGA FILAVGSPVG
VSRSIDIGNI TVIDKNASFF DGYGRVIYCD KHLDSVGTFL LDTSGNLVGV VSNLDDSSSI
SMAYGISDLK VLIENMTNGV GSAYLGVRAL DIDKDKAPEG MPSGIYVSEV RADSPAYNIG
IQSGDIISMI GNEEVNSITG FKNIMEKLKP NQVVNIKVNR SGKDGFTELN FETTIGARS
//
