ID J4VRK2_BEAB2 Unreviewed; 831 AA.
AC J4VRK2;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Subtilase-like protein {ECO:0000313|EMBL:EJP61235.1};
GN ORFNames=BBA_09812 {ECO:0000313|EMBL:EJP61235.1};
OS Beauveria bassiana (strain ARSEF 2860) (White muscardine disease fungus)
OS (Tritirachium shiotae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Beauveria.
OX NCBI_TaxID=655819 {ECO:0000313|EMBL:EJP61235.1, ECO:0000313|Proteomes:UP000002762};
RN [1] {ECO:0000313|EMBL:EJP61235.1, ECO:0000313|Proteomes:UP000002762}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 2860 {ECO:0000313|EMBL:EJP61235.1,
RC ECO:0000313|Proteomes:UP000002762};
RX PubMed=22761991; DOI=10.1038/srep00483;
RA Xiao G., Ying S.H., Zheng P., Wang Z.L., Zhang S., Xie X.Q., Shang Y.,
RA St Leger R.J., Zhao G.P., Wang C., Feng M.G.;
RT "Genomic perspectives on the evolution of fungal entomopathogenicity in
RT Beauveria bassiana.";
RL Sci. Rep. 2:483-483(2012).
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JH725218; EJP61235.1; -; Genomic_DNA.
DR RefSeq; XP_008603131.1; XM_008604909.1.
DR AlphaFoldDB; J4VRK2; -.
DR STRING; 655819.J4VRK2; -.
DR GeneID; 19892824; -.
DR HOGENOM; CLU_003559_3_2_1; -.
DR InParanoid; J4VRK2; -.
DR OrthoDB; 2493625at2759; -.
DR Proteomes; UP000002762; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd07489; Peptidases_S8_5; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR010435; Fn3_5.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034187; Peptidases_S8_5.
DR PANTHER; PTHR43806:SF59; CEREVISIN-RELATED; 1.
DR PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR Pfam; PF06280; fn3_5; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00136; SUBTILASE_ASP; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000002762};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}.
FT DOMAIN 176..426
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 460..571
FT /note="Fn3-like"
FT /evidence="ECO:0000259|Pfam:PF06280"
FT ACT_SITE 185
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 226
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 388
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 831 AA; 89175 MW; 835E8D7B231EA97B CRC64;
MTSPLIKTKS PTAHHSTYFS SSHNLFSDSM VHFSALTLAR LATAAASLAG AATIDSKPVP
SDYITGASIL ECESSRNLAL LVKAVQDQGG TIRRQFNSSV FYGLSVQLPN TTMAEHGMEL
MEQMPGVVRV WPVEVTRQPV EIQTEHPAAY QRRGNSAPWN HVMTQVDKLH AEGFTGSGIR
VAVIDTGIDY THPALGGCFG KGCRVALGEN FSQDGDKNDP MDCQGHGTRV ASILAEMMPI
SVADCDGEMK VDDVIAAWIK AHEDGAQIVV SSTLLSQGTS WAMHPAAAVV SRIVDSGVPC
IVGVGNDRQA GLFSVASPSS GKGVTTVSGF SWAPDSVDGD IIKDTPMARF SSYGPNWDLD
IKPTVGASAV NVTVASLHGG YKEVSGTSYS GPFVGGIMAL MAEVRGSFDP VLLNSLLTST
AVPQGAPQGA PASVAEQGGG LVRAWDAAHA TTLVKPASLA FNDTLHRAQF LTLHITNTAK
EDVTYRLDAL TADTLYTFVS SRPSVGQSPP VHESAVIEIS QRDLVLGPGR SASVNISVTD
PIGLDPGRLP VWSGWIAINS SNSGLLTIPY LGLSGSLKDQ PIIVSGGVSL LEHYNPWYEA
EDKDLQDGGL IRYRITDDNS WGLVAQVRIR PSLGTRLVRA EVVPVSPRKW LADRLQDRNL
TAFTLEMFSH TEGIYETWNG RLASGDYIPT GRYKLAVRAL RLFGDPNIES DWDLLETVTF
QVPTGGGEKV CEMYRSRQAK ISQNALFDSH QECLLVHGGV LKDIPWFDEP QNGSLCTKDS
LTDESCGTLK FCNAHNNNLS QGLKSPFLSS SDCFSSHKWP LWAFPPSSSE S
//
