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Database: UniProt
Entry: J5PNP0_9RHOB
LinkDB: J5PNP0_9RHOB
Original site: J5PNP0_9RHOB 
ID   J5PNP0_9RHOB            Unreviewed;       509 AA.
AC   J5PNP0;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   05-JUL-2017, entry version 34.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=A33M_2514 {ECO:0000313|EMBL:EJW12037.1};
OS   Rhodovulum sp. PH10.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Rhodovulum.
OX   NCBI_TaxID=1187851 {ECO:0000313|EMBL:EJW12037.1, ECO:0000313|Proteomes:UP000002930};
RN   [1] {ECO:0000313|EMBL:EJW12037.1, ECO:0000313|Proteomes:UP000002930}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PH10 {ECO:0000313|EMBL:EJW12037.1,
RC   ECO:0000313|Proteomes:UP000002930};
RX   PubMed=23105089; DOI=10.1128/JB.01695-12;
RA   Khatri I., Nupur, Korpole S., Subramanian S., Pinnaka A.K.;
RT   "Draft Genome Sequence of Rhodovulum sp. Strain PH10, a Phototrophic
RT   Alphaproteobacterium Isolated from a Soil Sample of Mangrove of
RT   Namkhana, India.";
RL   J. Bacteriol. 194:6363-6363(2012).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EJW12037.1}.
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DR   EMBL; AKZI01000040; EJW12037.1; -; Genomic_DNA.
DR   RefSeq; WP_008385602.1; NZ_AKZI01000040.1.
DR   EnsemblBacteria; EJW12037; EJW12037; A33M_2514.
DR   PATRIC; fig|1187851.3.peg.1709; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000002930; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002930};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002930}.
FT   DOMAIN      202    328       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      417    486       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     210    217       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   509 AA;  55600 MW;  F1ACC6391F69FB80 CRC64;
     MTNNHQERWT RVKGRLRAEV GDDIYSSWFA RMELESVESE TVRLSVPTRF LKSWIQSHYA
     ERVLACWQGE EPAVRRIDLS VRSAMLRHPP GARPGVPAAD QAAAGRAGTG HAGMGHAGLD
     RAADGHVMGG YGGGHATTNG HGFPSLAEPG TGRPGAGGHE TLGGSPLDPR LTFETFVVGR
     SNSLAHAAAK QVATAGRGDA VMFNPLYVHS AVGLGKTHLL QAIAWAGNAS GARRVLYLTA
     EKFVYGFVSS LRQQTTLAFK EVLRTTDVLL IDDLQFLQGK STHAEFSHTL NAMIDAGRQV
     VVAADRPPLD LENLDDRVRS RLAGGLVVEM GSFGEDLRLE ILQSRVASAR THHAAFDVPA
     DVLDFIAKAV THNGRDLEGA VNRLLAHSKL TGQPVTMELA EREIRDLVRP QEPRKVKIEE
     IQRIVARRYN VSRSDLLSSR RTANVVRPRQ IAMYLAKTLT LRSLPEIGRR FGGRDHTTVL
     HAVRKIEGLV GNDTTLADEI EAIKRELQE
//
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