ID J7L679_NOCAA Unreviewed; 1989 AA.
AC J7L679;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Condensation domain protein {ECO:0000313|EMBL:AFR05982.1};
GN OrderedLocusNames=B005_2050 {ECO:0000313|EMBL:AFR05982.1};
OS Nocardiopsis alba (strain ATCC BAA-2165 / BE74).
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Nocardiopsaceae; Nocardiopsis.
OX NCBI_TaxID=1205910 {ECO:0000313|EMBL:AFR05982.1, ECO:0000313|Proteomes:UP000003779};
RN [1] {ECO:0000313|EMBL:AFR05982.1, ECO:0000313|Proteomes:UP000003779}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-2165 / BE74 {ECO:0000313|Proteomes:UP000003779};
RX PubMed=23105086; DOI=10.1128/JB.01522-12;
RA Qiao J., Chen L., Li Y., Wang J., Zhang W., Chen S.;
RT "Whole-Genome Sequence of Nocardiopsis alba Strain ATCC BAA-2165,
RT Associated with Honeybees.";
RL J. Bacteriol. 194:6358-6359(2012).
RN [2] {ECO:0000313|Proteomes:UP000003779}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-2165 / BE74 {ECO:0000313|Proteomes:UP000003779};
RA Qiao J., Chen L., Li Y., Wang J., Zhang W., Chen S.;
RT "Whole-genome sequence of Nocardiopsis alba strain ATCC BAA-2165 associated
RT with honeybees.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003788; AFR05982.1; -; Genomic_DNA.
DR RefSeq; WP_014908450.1; NC_018524.1.
DR STRING; 1205910.B005_2050; -.
DR KEGG; nal:B005_2050; -.
DR PATRIC; fig|1205910.3.peg.1938; -.
DR eggNOG; COG1020; Bacteria.
DR eggNOG; COG3321; Bacteria.
DR eggNOG; COG3433; Bacteria.
DR HOGENOM; CLU_234118_0_0_11; -.
DR OrthoDB; 4537517at2; -.
DR Proteomes; UP000003779; Chromosome.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.30.70.3290; -; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.30.70.250; Malonyl-CoA ACP transacylase, ACP-binding; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR InterPro; IPR032821; PKS_assoc.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF37; FATTY ACID SYNTHASE; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF00668; Condensation; 1.
DR Pfam; PF16197; KAsynt_C_assoc; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SMART; SM00827; PKS_AT; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000003779};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 13..443
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 1349..1423
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 1989 AA; 218267 MW; 0259DFC01C3AC728 CRC64;
MSDATEPDYR YTGLEIAVIG MAGRFPSAAS VEDLWSNLLA GVEGISRFDD DELIEMGVSP
KALEDEHYVR AKGVFPDIEY FDSRFFNYTP ADATVLDPQV RALHEEVYHA LEDAGYSAEG
RKEAIGLFLG ATNNMPWEVD TQRRFNEDAG SAFSGMQLND KDFAATRISH SLGLRGPAFT
LHTACSSSLV AIDVACRNVW TGSCQIALAG GSGLSLPHKN GYQHRPNMVH SPDGHCRAFD
AAAGGTVEGN GVGIVVLKRL EAALRDGDRV YAVIKGSAVN NDGTRKVGYT APSIEGQAEV
IRKAHRVAGV KPSEISYVEA HGTGTALGDP VEMEALSKAF GPGEPDSCGV GSLKASIGHL
DTAAGVASFI KACKVLKERT IPQSLHFDTL NPGIRLDGTP FYIAGERQEM RRKRSESGRE
LPLRAGVSAF GIGGTNAHLV LEEAPEPRRP ASDGRAHNTF VLSAASGEAI TRMKRDFVDH
LAANPDIDGA DLAWTLQNRQ RDLPYRYAVG FGGIGRLRER LQESLDAGDE PAHLPRNGRR
DVYLLFSGAG AQHLRMARGL YETESVFRAR VDDCLAITDE LGSPVVREVF FGETVAQEKQ
LNNIAVSLVL LFVVEYSMAR TLLDWGIRPR GMIGHSTGEL VAACVAGVFS LEDGLRLVLA
RGSLVDTTPE GAVTSVKASE DTIRPMLTDE LSIAAVNAPE DCTVSGASAA IAAFEERCAE
QGITFTHVEA AHAYHSQYME PILEEYREIA SSVDLRAPEI PYVSNVTGTW VTPEQATDPD
YYCEHIRRTV RFKDGVETIM ERGDALFVEV GPGKSLSSFV RGTARGTRTG AINMLRHRLE
EVDDGEHLAT AIRKLWEAGV ALDWPAFHKG RAPSKVRLPL YAFDRTEYPI DIGEFQQLLS
TADDRPRPVV ERRPVSVPAT GAPRHALQLT WSSALLPDSG ESGRHRVLLV FTEDRSRIRR
VMDEVPYWTP LYVEFGGEYR FDGAVGARVR RGHEDDLRRL AADLEEHALV GDTVVVHHRP
GADASVLVRR LCDVVSGLRD RPVRDLVLLE TVAPAGPEGS PLPEMIGLNL EYPHLRVRAL
GCDTALTAPG GPRAWSESLR RELEAEREEA VAARYRDGGR FVPAMVPLHG HRGRSAARSG
RTVVVCPVDA VDDVLSATGP ERSVDVLPFA VGADGPTEAG ARTEGRSTVM AAVTGRTGAD
TTEGLISRLR ALKGTTHLVL WDTSLRDAAR TGSDASDAPD PGTLSRRLRE AGDELGTSYG
VVSRADLDRF EWNADVTARF ARNAVTDAEA DGVRLYSFGR LGDGDPSVLD LLYEMRVSGM
RTGYHGLDLL ETAATRKAIG EPEESGAVDE RSSVAAVIER EMADLLGLEG IDARADLFDT
GLDSLKLIQF TSALERHGYT VLASDVHSHP TIGELAGLLA RSDKQVNQEC DSLESAAALL
GERLESGCAL YEITAGADEE ESVVLFVDGF REEDRVSIVR RINELRLPQA FTPHYILPRE
AERDFLAGRD FASLRLGGDP TREGGLDRLF GEIDRRQEDM RRSILSRPVR WTYPISGTQK
HYFSRGARPQ LYLVQFRELI DVDVLERALG DVVGRHGLMR SVLVRSLGRR MWKEHEPPMT
FTLPRIDLSA LPLRRQEEVR AELVKREWNV DLKTDTILYQ AVLVKYNERS YDMIFQFDHS
IFDGASGQAF RADLVKRYQE LAEGTTRALP RTRSFRHLKE QTGKGPVGIG ADEIIERFDL
EAWGRYGKEI LAASEGRGTG RMCDVRYSVD LRRLQSGDGE DVEPFSLVLY LYARLVARLL
GVDKVALDLV FNSRVYEDVD YSGVMGMVAD VLPLVVSGEQ GVREDLEVLI QQKFQSMNKF
NVNFSNLVTG PLTALKYGKV FQTTKEARGT GFRPSCMLNF AGSTEAEYDA IWDMTLELLT
EDQDTLDYAD CYCVSKVSGT RQDIVILSTW VEDPAEVVSI LDEEVEYLAR RAAAESGESD
VNVESEGAR
//
