ID J7L7G9_NOCAA Unreviewed; 405 AA.
AC J7L7G9;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Actinorhodin polyketide putative beta-ketoacyl synthase 2 {ECO:0000313|EMBL:AFR07405.1};
DE EC=2.3.1.- {ECO:0000313|EMBL:AFR07405.1};
GN OrderedLocusNames=B005_0616 {ECO:0000313|EMBL:AFR07405.1};
OS Nocardiopsis alba (strain ATCC BAA-2165 / BE74).
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Nocardiopsaceae; Nocardiopsis.
OX NCBI_TaxID=1205910 {ECO:0000313|EMBL:AFR07405.1, ECO:0000313|Proteomes:UP000003779};
RN [1] {ECO:0000313|EMBL:AFR07405.1, ECO:0000313|Proteomes:UP000003779}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-2165 / BE74 {ECO:0000313|Proteomes:UP000003779};
RX PubMed=23105086; DOI=10.1128/JB.01522-12;
RA Qiao J., Chen L., Li Y., Wang J., Zhang W., Chen S.;
RT "Whole-Genome Sequence of Nocardiopsis alba Strain ATCC BAA-2165,
RT Associated with Honeybees.";
RL J. Bacteriol. 194:6358-6359(2012).
RN [2] {ECO:0000313|Proteomes:UP000003779}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-2165 / BE74 {ECO:0000313|Proteomes:UP000003779};
RA Qiao J., Chen L., Li Y., Wang J., Zhang W., Chen S.;
RT "Whole-genome sequence of Nocardiopsis alba strain ATCC BAA-2165 associated
RT with honeybees.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
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DR EMBL; CP003788; AFR07405.1; -; Genomic_DNA.
DR AlphaFoldDB; J7L7G9; -.
DR STRING; 1205910.B005_0616; -.
DR KEGG; nal:B005_0616; -.
DR PATRIC; fig|1205910.3.peg.578; -.
DR eggNOG; COG0304; Bacteria.
DR HOGENOM; CLU_000022_69_2_11; -.
DR OrthoDB; 416758at2; -.
DR Proteomes; UP000003779; Chromosome.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF322; POLYKETIDE BETA-KETOACYL SYNTHASE 2-RELATED; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000313|EMBL:AFR07405.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000003779};
KW Transferase {ECO:0000256|RuleBase:RU003694, ECO:0000313|EMBL:AFR07405.1}.
FT DOMAIN 2..401
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 405 AA; 41907 MW; 24DBA79E655B3FB0 CRC64;
MTMDTVITGL GTVSPAGLGV EAYWEALVEG RTLIAPIPDF DTEGFHVHLG GKVPGFDPYD
HIEGRFVVQT DAFTRFALVA AEEALRDSGV DTSVDPYATG ALICSGAGGV EFGQREIEAL
WSEGPDRVGP YQSIAWFYAA STGQVSIRNG LKGMCGVLVT DEPGMLDALG QSARTLRRGT
SSMLVGGAEA PIGSPFSLAC QVGSEVLSPG FDPTTAYVPF TEGATGHVPA EGAAVALVER
ADVARERGAR IRAVVAGQAS TFGGIGVFDP GGEGLLWAAR QAMERAGVSP EEVDVVFADA
VGLPKADADE AATIRRLFPK GVAVTAPKTG FGRAYAGAGA LDVAAAVLSL EHRIIPPTPH
VLDAPFGLDL VVRVPRPARP RTALVLSRGM GGANSAVVLK HPEHA
//
