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Database: UniProt
Entry: J7L7J3_NOCAA
LinkDB: J7L7J3_NOCAA
Original site: J7L7J3_NOCAA 
ID   J7L7J3_NOCAA            Unreviewed;       591 AA.
AC   J7L7J3;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   05-JUL-2017, entry version 38.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:AFR09583.1};
GN   OrderedLocusNames=B005_1966 {ECO:0000313|EMBL:AFR09583.1};
OS   Nocardiopsis alba (strain ATCC BAA-2165 / BE74).
OC   Bacteria; Actinobacteria; Streptosporangiales; Nocardiopsaceae;
OC   Nocardiopsis.
OX   NCBI_TaxID=1205910 {ECO:0000313|EMBL:AFR09583.1, ECO:0000313|Proteomes:UP000003779};
RN   [1] {ECO:0000313|Proteomes:UP000003779}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-2165 / BE74 {ECO:0000313|Proteomes:UP000003779};
RA   Qiao J., Chen L., Li Y., Wang J., Zhang W., Chen S.;
RT   "Whole-genome sequence of Nocardiopsis alba strain ATCC BAA-2165
RT   associated with honeybees.";
RL   Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP003788; AFR09583.1; -; Genomic_DNA.
DR   EnsemblBacteria; AFR09583; AFR09583; B005_1966.
DR   KEGG; nal:B005_1966; -.
DR   PATRIC; fig|1205910.3.peg.1857; -.
DR   KO; K02313; -.
DR   OMA; ATHIERN; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000003779; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000003779};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003779}.
FT   DOMAIN      283    413       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      495    563       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     291    298       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   591 AA;  65054 MW;  D326EF4862125073 CRC64;
     MDGIDNDALP AHQRAWLPQT RPLGLIEDTA LIAAPNEFTK KVLESRLHPA ISKALSAHLG
     REIRVAVTVD PTAVPTPPPT PSPYGGPREP VPGPFSPGRD QGPALPDHTP PVSEPRPSPA
     RPSFQEPRGQ HARPASPPAP ETSAETPGLQ ETPPETPASW GAAGGWPTQE ELWRQQGWGE
     ADWDRPNRWE TPASEAAETP EVGTVAPNEV EDAKTAEEEP PESARPAAEA PSPTAPPGRS
     PEIPPGDHAR LNPKYTFDTF VIGSSNRFAH AASVAAAEAP AKAYNPLFIH GGSGLGKTHL
     LHAIGHYTHR LYEGSRVRYV SSEEFTNEFI NSIRDGKADG FRRRYRDIDV LLVDDIQFLE
     NKEQTQEEFF HTFNTLHNSD KQIVISSDRP PKQLTTLEDR MRSRFEWGLL TDVQPPELET
     RIAILRKKAA QEGLAAPPEV LEFIASKIST NIRELEGALI RVTAFASLNR QSVDLDLTGQ
     VLRDLVPSSE VPEITASTIM SQTAAYFGLS LEDLCGTSRS RVLVTARQIA MYLCRELTDL
     SLPKIGQQFG RDHTTVMHAD RKVRALMAER RSIYNQVHEL TSRIKDQPTL T
//
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