ID J7Q7H8_ECOLX Unreviewed; 317 AA.
AC J7Q7H8; A0A2A2XPM1;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE RecName: Full=Transcriptional regulator LsrR {ECO:0000256|ARBA:ARBA00015912};
GN Name=lsrR {ECO:0000313|EMBL:HAH1419500.1};
GN ORFNames=A9X72_12630 {ECO:0000313|EMBL:AVU66022.1}, ACN81_11635
GN {ECO:0000313|EMBL:OKU25019.1}, BANRA_02116
GN {ECO:0000313|EMBL:VCY83458.1}, BG944_004058
GN {ECO:0000313|EMBL:EFI0214821.1}, BvCmsSIP010_00398
GN {ECO:0000313|EMBL:GDV09414.1}, C1Q91_003722
GN {ECO:0000313|EMBL:EFA9847276.1}, CF22_003859
GN {ECO:0000313|EMBL:EFM0517806.1}, CR538_13065
GN {ECO:0000313|EMBL:AUK01269.1}, DRW19_16930
GN {ECO:0000313|EMBL:EAA6665171.1}, DS732_12980
GN {ECO:0000313|EMBL:AXO07203.1}, E5H86_13040
GN {ECO:0000313|EMBL:EFC2246720.1}, EAX79_20505
GN {ECO:0000313|EMBL:EAB0920068.1}, EN85_003218
GN {ECO:0000313|EMBL:EFL9838199.1}, FJQ40_16650
GN {ECO:0000313|EMBL:EFB1699028.1}, FVB16_18860
GN {ECO:0000313|EMBL:MPU50855.1}, GAI89_17730
GN {ECO:0000313|EMBL:EFH6096468.1}, GAJ12_18960
GN {ECO:0000313|EMBL:EFH6167108.1}, HHH44_002915
GN {ECO:0000313|EMBL:HAH1419500.1}, HV209_06800
GN {ECO:0000313|EMBL:MBA7718316.1}, NCTC8009_04325
GN {ECO:0000313|EMBL:SQD03825.1}, NCTC8179_03582
GN {ECO:0000313|EMBL:STK87767.1}, NCTC8333_02974
GN {ECO:0000313|EMBL:STM24012.1}, NCTC8622_05250
GN {ECO:0000313|EMBL:STI86134.1}, RG28_14695
GN {ECO:0000313|EMBL:APJ77456.1};
OS Escherichia coli.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=562 {ECO:0000313|EMBL:HAH1419500.1};
RN [1] {ECO:0000313|EMBL:APJ77456.1, ECO:0000313|Proteomes:UP000184379}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C5 {ECO:0000313|EMBL:APJ77456.1,
RC ECO:0000313|Proteomes:UP000184379};
RA Jiang J., Xu Z., Zhou Y., Zhao H., Leung F.C.C.;
RT "Vertical and Horizontal Evolutionary Story implied from E. coli complete
RT genomes.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:OKU25019.1, ECO:0000313|Proteomes:UP000186275}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=703098 {ECO:0000313|EMBL:OKU25019.1,
RC ECO:0000313|Proteomes:UP000186275};
RA Del Canto F., Vidal R., Stine O.C., Pop M.;
RT "Chaperone-usher pili loci of human colonization factor-negative
RT enterotoxigenic Escherichia coli.";
RL Front. Cell. Infect. Microbiol. 0:0-0(2017).
RN [3] {ECO:0000313|EMBL:AVU66022.1, ECO:0000313|Proteomes:UP000325046}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=190 {ECO:0000313|EMBL:AVU66022.1,
RC ECO:0000313|Proteomes:UP000325046};
RA Hoffmann M., Sanchez M., Timme R., Bry L.;
RT "Whole genome sequencing of cultured foodborne pathogen.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:AUK01269.1, ECO:0000313|Proteomes:UP000234238}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=14EC029 {ECO:0000313|EMBL:AUK01269.1,
RC ECO:0000313|Proteomes:UP000234238};
RA Li B., Wang X.;
RT "mcr-1 positive E.coli isolates in China.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:HAH1419500.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W1_5_ERB1 {ECO:0000313|EMBL:HAH1419500.1};
RX PubMed=30286803;
RA Souvorov A., Agarwala R., Lipman D.J.;
RT "SKESA: strategic k-mer extension for scrupulous assemblies.";
RL Genome Biol. 19:153-153(2018).
RN [6] {ECO:0000313|EMBL:GDV09414.1, ECO:0000313|Proteomes:UP000300554}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SI-P010 {ECO:0000313|EMBL:GDV09414.1,
RC ECO:0000313|Proteomes:UP000300554};
RA Arimizu Y., Ogura Y.;
RT "Large scale genomics of bovine and human commensal E. coli to reveal the
RT emerging process of EHEC.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
RN [7] {ECO:0000313|Proteomes:UP000250991, ECO:0000313|Proteomes:UP000254079}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC8009 {ECO:0000313|EMBL:SQD03825.1,
RC ECO:0000313|Proteomes:UP000250991}, NCTC8179
RC {ECO:0000313|EMBL:STK87767.1, ECO:0000313|Proteomes:UP000255543},
RC NCTC8333 {ECO:0000313|EMBL:STM24012.1,
RC ECO:0000313|Proteomes:UP000254718}, and NCTC8622
RC {ECO:0000313|EMBL:STI86134.1, ECO:0000313|Proteomes:UP000254079};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [8] {ECO:0000313|EMBL:EAA6665171.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=559781 {ECO:0000313|EMBL:EAA6665171.1};
RA Ashton P.M., Dallman T., Nair S., De Pinna E., Peters T., Grant K.;
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
RN [9] {ECO:0000313|EMBL:AXO07203.1, ECO:0000313|Proteomes:UP000256244}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cq9 {ECO:0000313|Proteomes:UP000256244}, and Cq9
RC {ECO:0000313|EMBL:AXO07203.1};
RA Bai L.;
RT "Complete genome sequencing and genomic characterization of five
RT Escherichia coli strains co-producing MCR-1 and ESBLs from different
RT origins in China.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
RN [10] {ECO:0000313|EMBL:HAH1419500.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=W1_5_ERB1 {ECO:0000313|EMBL:HAH1419500.1};
RG NCBI Pathogen Detection Project;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
RN [11] {ECO:0000313|Proteomes:UP000523388, ECO:0000313|Proteomes:UP000528504}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AZ-TG102963 {ECO:0000313|EMBL:EFA9847276.1,
RC ECO:0000313|Proteomes:UP000523388}, AZ-TG60901
RC {ECO:0000313|EMBL:EFM0517806.1, ECO:0000313|Proteomes:UP000528504},
RC AZ-TG73583 {ECO:0000313|EMBL:EFL9838199.1,
RC ECO:0000313|Proteomes:UP000543257}, and PSU-1847
RC {ECO:0000313|EMBL:EFB1699028.1, ECO:0000313|Proteomes:UP000533284};
RG GenomeTrakr network: Whole genome sequencing for foodborne pathogen traceback;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
RN [12] {ECO:0000313|EMBL:VCY83458.1, ECO:0000313|Proteomes:UP000281521}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ecoli022 {ECO:0000313|EMBL:VCY83458.1};
RA Noll B N.;
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
RN [13] {ECO:0000313|EMBL:EFC2246720.1, ECO:0000313|Proteomes:UP000531916}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CVM N19EC0510 {ECO:0000313|EMBL:EFH6096468.1,
RC ECO:0000313|Proteomes:UP000531463}, CVM N19EC0596
RC {ECO:0000313|EMBL:EFH6167108.1, ECO:0000313|Proteomes:UP000537181},
RC and FSIS11919500 {ECO:0000313|EMBL:EFC2246720.1,
RC ECO:0000313|Proteomes:UP000531916};
RG NARMS: The National Antimicrobial Resistance Monitoring System;
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
RN [14] {ECO:0000313|EMBL:MPU50855.1, ECO:0000313|Proteomes:UP000392867}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WU2356 {ECO:0000313|EMBL:MPU50855.1,
RC ECO:0000313|Proteomes:UP000392867};
RA Neumann N.;
RT "Identification of Water Treatment Resistant and Multidrug Resistant
RT Urinary Pathogenic Escherichia coli in Wastewater.";
RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases.
RN [15] {ECO:0000313|EMBL:EFI0214821.1, ECO:0000313|Proteomes:UP000521994}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2014C-3796 {ECO:0000313|EMBL:EFI0214821.1,
RC ECO:0000313|Proteomes:UP000521994}, and PNUSAE019345
RC {ECO:0000313|EMBL:EAB0920068.1};
RG PulseNet: The National Subtyping Network for Foodborne Disease Surveillance;
RA Tarr C.L., Trees E., Katz L.S., Carleton-Romer H.A., Stroika S.,
RA Kucerova Z., Roache K.F., Sabol A.L., Besser J., Gerner-Smidt P.;
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
RN [16] {ECO:0000313|EMBL:MBA7718316.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=RHBSTW-00474 {ECO:0000313|EMBL:MBA7718316.1};
RA Shaw L.P.;
RT "REHAB project genomes.";
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the SorC transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00010466}.
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DR EMBL; CP010122; APJ77456.1; -; Genomic_DNA.
DR EMBL; CP024141; AUK01269.1; -; Genomic_DNA.
DR EMBL; CP020520; AVU66022.1; -; Genomic_DNA.
DR EMBL; CP031546; AXO07203.1; -; Genomic_DNA.
DR EMBL; AAACEW010000021; EAA6665171.1; -; Genomic_DNA.
DR EMBL; AAADNP010000030; EAB0920068.1; -; Genomic_DNA.
DR EMBL; AASCJS010000024; EFA9847276.1; -; Genomic_DNA.
DR EMBL; AASDBN010000034; EFB1699028.1; -; Genomic_DNA.
DR EMBL; AASEPP010000018; EFC2246720.1; -; Genomic_DNA.
DR EMBL; AASWKH010000017; EFH6096468.1; -; Genomic_DNA.
DR EMBL; AASWKX010000026; EFH6167108.1; -; Genomic_DNA.
DR EMBL; AASXRC010000026; EFI0214821.1; -; Genomic_DNA.
DR EMBL; AATJKW010000020; EFL9838199.1; -; Genomic_DNA.
DR EMBL; AATJQG010000023; EFM0517806.1; -; Genomic_DNA.
DR EMBL; BGIE01000003; GDV09414.1; -; Genomic_DNA.
DR EMBL; DABALL010000016; HAH1419500.1; -; Genomic_DNA.
DR EMBL; JABXPW010000002; MBA7718316.1; -; Genomic_DNA.
DR EMBL; VOTT01000515; MPU50855.1; -; Genomic_DNA.
DR EMBL; LGMY01000117; OKU25019.1; -; Genomic_DNA.
DR EMBL; UARW01000010; SQD03825.1; -; Genomic_DNA.
DR EMBL; UGCP01000002; STI86134.1; -; Genomic_DNA.
DR EMBL; UGEB01000001; STK87767.1; -; Genomic_DNA.
DR EMBL; UGFE01000002; STM24012.1; -; Genomic_DNA.
DR EMBL; UWXJ01000001; VCY83458.1; -; Genomic_DNA.
DR RefSeq; WP_000154340.1; NZ_WVWF01000017.1.
DR STRING; 585034.ECIAI1_1524; -.
DR GeneID; 75202160; -.
DR PATRIC; fig|562.10471.peg.2073; -.
DR OMA; CTVVQLT; -.
DR Proteomes; UP000184379; Chromosome.
DR Proteomes; UP000186275; Unassembled WGS sequence.
DR Proteomes; UP000234238; Chromosome.
DR Proteomes; UP000250991; Unassembled WGS sequence.
DR Proteomes; UP000254079; Unassembled WGS sequence.
DR Proteomes; UP000254718; Unassembled WGS sequence.
DR Proteomes; UP000255543; Unassembled WGS sequence.
DR Proteomes; UP000256244; Chromosome.
DR Proteomes; UP000281521; Unassembled WGS sequence.
DR Proteomes; UP000300554; Unassembled WGS sequence.
DR Proteomes; UP000325046; Chromosome.
DR Proteomes; UP000392867; Unassembled WGS sequence.
DR Proteomes; UP000521994; Unassembled WGS sequence.
DR Proteomes; UP000523388; Unassembled WGS sequence.
DR Proteomes; UP000528504; Unassembled WGS sequence.
DR Proteomes; UP000531463; Unassembled WGS sequence.
DR Proteomes; UP000531916; Unassembled WGS sequence.
DR Proteomes; UP000533284; Unassembled WGS sequence.
DR Proteomes; UP000537181; Unassembled WGS sequence.
DR Proteomes; UP000543257; Unassembled WGS sequence.
DR Proteomes; UP000622722; Unassembled WGS sequence.
DR Proteomes; UP000844228; Unassembled WGS sequence.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1360; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR007324; Sugar-bd_dom_put.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR34294:SF12; TRANSCRIPTIONAL REGULATOR LSRR; 1.
DR PANTHER; PTHR34294; TRANSCRIPTIONAL REGULATOR-RELATED; 1.
DR Pfam; PF04198; Sugar-bind; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125}.
FT DOMAIN 67..315
FT /note="Sugar-binding"
FT /evidence="ECO:0000259|Pfam:PF04198"
SQ SEQUENCE 317 AA; 33814 MW; B60AA1F47B7DA3B4 CRC64;
MTINDSAISE QGMCEEEQVA RIAWFYYHDG LTQSEISDRL GLTRLKVSRL LEKGHQSGII
RVQINSRFEG CLEYETQLRR QFSLQHVRVI PGLADADVGG RLGIGAAHML MSLLQPQQML
AIGFGEATMN TLQRLSGFIS SQQIRLVTLS GGVGSYMTGI GQLNAACSVN IIPAPLRASS
ADIARTLKNE NCVKDVLLAA QAADVAIVGI GAVSQQDDAT IIRSGYISQG EQLMIGRKGA
VGDILGYFFD AKGDVVTDIK IHNELIGLPL SSLKTIPVRV GVAGGENKAE AIAAAMKGGY
INALVTDQDT AAAILRS
//
