ID J7QBA9_ECOLX Unreviewed; 551 AA.
AC J7QBA9;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Alpha,alpha-phosphotrehalase {ECO:0000313|EMBL:MBB2466403.1};
DE SubName: Full=Trehalose-6-P hydrolase {ECO:0000313|EMBL:GDH51104.1};
DE SubName: Full=Trehalose-6-phosphate hydrolase {ECO:0000313|EMBL:KNF70518.1};
DE EC=3.2.1.93 {ECO:0000313|EMBL:KNF70518.1, ECO:0000313|EMBL:MBB2466403.1};
GN Name=treC {ECO:0000313|EMBL:GDH51104.1};
GN ORFNames=BK292_11790 {ECO:0000313|EMBL:OJM95149.1}, BvCmsKKP061_03428
GN {ECO:0000313|EMBL:GDH51104.1}, G9448_11855
GN {ECO:0000313|EMBL:QLA43677.1}, H0O72_05280
GN {ECO:0000313|EMBL:NZD13026.1}, HEP30_009840
GN {ECO:0000313|EMBL:MBB2466403.1}, HV109_21125
GN {ECO:0000313|EMBL:QLY98921.1}, O5851_08565
GN {ECO:0000313|EMBL:MCZ5093707.1}, WR15_06645
GN {ECO:0000313|EMBL:KNF70518.1};
OS Escherichia coli.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=562 {ECO:0000313|EMBL:KNF70518.1, ECO:0000313|Proteomes:UP000037564};
RN [1] {ECO:0000313|EMBL:KNF70518.1, ECO:0000313|Proteomes:UP000037564}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CFSAN026843 {ECO:0000313|EMBL:KNF70518.1,
RC ECO:0000313|Proteomes:UP000037564};
RA Gonzalez-Escalona N., Toro M., Timme R., Payne J.;
RT "Genome sequences of 64 non-O157:H7 Shiga toxin-producing Escherichia coli
RT strains.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:OJM95149.1, ECO:0000313|Proteomes:UP000184369}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=634 {ECO:0000313|EMBL:OJM95149.1,
RC ECO:0000313|Proteomes:UP000184369};
RA Wang Y., Zhang R., Li J., Wu Z., Wenjuan Y., Schwarz S., Tyrrell J.,
RA Zheng Y., Wang S., Shen Z., Liu Z., Lei L., Li M., Zhang Q., Wu C.,
RA Zhang Q., Wu Y., Walsh T., Shen J.;
RT "Comprehensive resistome analysis reveals the prevalence of NDM and MCR-1
RT in Chinese poultry production.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:GDH51104.1, ECO:0000313|Proteomes:UP000303027}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KK-P061 {ECO:0000313|EMBL:GDH51104.1,
RC ECO:0000313|Proteomes:UP000303027};
RA Arimizu Y., Ogura Y.;
RT "Large scale genomics of bovine and human commensal E. coli to reveal the
RT emerging process of EHEC.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:QLA43677.1, ECO:0000313|Proteomes:UP000509457}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARL09/232 {ECO:0000313|EMBL:QLA43677.1,
RC ECO:0000313|Proteomes:UP000509457};
RA Olivera C.D., Rakonjac J.;
RT "Complete genome assembly of New Delhi metallo-beta-lactamase-1 (NDM-
RT 1)- producing Escherichia coli human isolate from New Zealand.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:QLY98921.1, ECO:0000313|Proteomes:UP000512182}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RHBSTW-00177 {ECO:0000313|EMBL:QLY98921.1,
RC ECO:0000313|Proteomes:UP000512182};
RA Shaw L.P.;
RT "REHAB project genomes.";
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EMBL:NZD13026.1, ECO:0000313|Proteomes:UP000543240}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PE01_346 {ECO:0000313|EMBL:NZD13026.1,
RC ECO:0000313|Proteomes:UP000543240};
RA Salvatierra G., Davila-Barclay A., Tsukayama P.;
RT "Market chickens as a source of antibiotic-resistant Escherichia coli in a
RT Peruvian shanty town.";
RL Submitted (JUL-2020) to the EMBL/GenBank/DDBJ databases.
RN [7] {ECO:0000313|EMBL:MBB2466403.1, ECO:0000313|Proteomes:UP000531761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=10.0349 {ECO:0000313|EMBL:MBB2466403.1,
RC ECO:0000313|Proteomes:UP000531761};
RA Lacher D.W., Mammel M.K., Gangiredla J., Gebru S.T., Barnaba T.J.,
RA Majowicz S.A., Dudley E.G.;
RT "Draft genome sequences of isolates of diverse host origin from the E. coli
RT Reference Center.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
RN [8] {ECO:0000313|EMBL:MCZ5093707.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=EC_E2BE_2_E_CuN_CeN {ECO:0000313|EMBL:MCZ5093707.1};
RA Sanderson H., Nnajibe C., Mccarthy M., Rubin J., Dillon J., White A.P.;
RT "Genome Hybrid Assemblies of 274 Avian and Broiler Barn Environment
RT Associated Escherichia coli Isolated from Saskatchewan Broiler Farms.";
RL Submitted (DEC-2022) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; BFXY01000103; GDH51104.1; -; Genomic_DNA.
DR EMBL; LGZN01000019; KNF70518.1; -; Genomic_DNA.
DR EMBL; JABWMK020000012; MBB2466403.1; -; Genomic_DNA.
DR EMBL; JAPXEC010000002; MCZ5093707.1; -; Genomic_DNA.
DR EMBL; JACCPE010000004; NZD13026.1; -; Genomic_DNA.
DR EMBL; MOGU01000020; OJM95149.1; -; Genomic_DNA.
DR EMBL; CP049967; QLA43677.1; -; Genomic_DNA.
DR EMBL; CP056794; QLY98921.1; -; Genomic_DNA.
DR RefSeq; WP_001348238.1; NZ_WVUT01000011.1.
DR PATRIC; fig|562.10477.peg.2721; -.
DR Proteomes; UP000037564; Unassembled WGS sequence.
DR Proteomes; UP000184369; Unassembled WGS sequence.
DR Proteomes; UP000303027; Unassembled WGS sequence.
DR Proteomes; UP000509457; Chromosome.
DR Proteomes; UP000512182; Chromosome.
DR Proteomes; UP000531761; Unassembled WGS sequence.
DR Proteomes; UP000543240; Unassembled WGS sequence.
DR Proteomes; UP001082551; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0008788; F:alpha,alpha-phosphotrehalase activity; IEA:UniProtKB-EC.
DR GO; GO:0005993; P:trehalose catabolic process; IEA:InterPro.
DR CDD; cd11333; AmyAc_SI_OligoGlu_DGase; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR022567; DUF3459.
DR InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR045857; O16G_dom_2.
DR InterPro; IPR012769; Trehalose_TreC.
DR NCBIfam; TIGR02403; trehalose_treC; 1.
DR PANTHER; PTHR10357; ALPHA-AMYLASE FAMILY MEMBER; 1.
DR PANTHER; PTHR10357:SF179; NEUTRAL AND BASIC AMINO ACID TRANSPORT PROTEIN RBAT; 1.
DR Pfam; PF00128; Alpha-amylase; 1.
DR Pfam; PF11941; DUF3459; 1.
DR SMART; SM00642; Aamy; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000313|EMBL:KNF70518.1};
KW Hydrolase {ECO:0000313|EMBL:KNF70518.1}.
FT DOMAIN 15..414
FT /note="Glycosyl hydrolase family 13 catalytic"
FT /evidence="ECO:0000259|SMART:SM00642"
SQ SEQUENCE 551 AA; 63818 MW; 9C4D2CDD5B29A0BD CRC64;
MTNLPHWWQN GVIYQIYPKS FQDTTGSGTG DLRGVIQRLD YLHKLGVDAI WLTPFYVSPQ
VDNGYDVANY TAIDPTYGTL DDFDELVTQA KSRGIRIILD MVFNHTSTQH AWFREALNKE
SPYRQFYIWR DGEPETPPNN WRSKFGGSAW RWHAESEQYY LHLFAPEQAD LNWENPAVRA
ELKKVCEFWA DRGVDGLRLD VVNLISKDPR FPEDLDGDGR RFYTDGPRAH EFLHEMNRDV
FTPRGLMTVG EMSSTSLEHC QRYAALTGSE LSMTFNFHHL KVDYPGGEKW TLAKPDFVAL
KTLFRHWQQG MHNVAWNALF WCNHDQPRIV SRFGDEGEYR VPAAKMLAMV LHGMQGTPYI
YQGEEIGMTN PHFTRITDYR DVESLNMFAE LRNDGRDADE LLAILASKSR DNSRTPMQWS
NGDNAGFTAG EPWIGLGDNY QQINVEAALT DESSVFYTYQ KLIALRKQEA VLTWGNYQDL
LPNSPVLWCY RREWKGQTLL VIANLSRGIQ PWQPGQMRGN WQLVMHNYEE ASPQPCAMNL
RPFEAVWWLQ K
//
