ID J7RGF3_KAZNA Unreviewed; 768 AA.
AC J7RGF3;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Potassium channel domain-containing protein {ECO:0000259|Pfam:PF07885};
GN Name=KNAG0B01800 {ECO:0000313|EMBL:CCK68623.1};
GN OrderedLocusNames=KNAG_0B01800 {ECO:0000313|EMBL:CCK68623.1};
OS Kazachstania naganishii (strain ATCC MYA-139 / BCRC 22969 / CBS 8797 / KCTC
OS 17520 / NBRC 10181 / NCYC 3082 / Yp74L-3) (Yeast) (Saccharomyces
OS naganishii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kazachstania.
OX NCBI_TaxID=1071383 {ECO:0000313|EMBL:CCK68623.1, ECO:0000313|Proteomes:UP000006310};
RN [1] {ECO:0000313|EMBL:CCK68623.1, ECO:0000313|Proteomes:UP000006310}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520
RC / NBRC 10181 / NCYC 3082 {ECO:0000313|Proteomes:UP000006310};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
RN [2] {ECO:0000313|Proteomes:UP000006310}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520
RC / NBRC 10181 / NCYC 3082 {ECO:0000313|Proteomes:UP000006310};
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Genome sequence of Kazachstania naganishii.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; HE978315; CCK68623.1; -; Genomic_DNA.
DR AlphaFoldDB; J7RGF3; -.
DR STRING; 1071383.J7RGF3; -.
DR eggNOG; KOG1418; Eukaryota.
DR HOGENOM; CLU_013394_2_0_1; -.
DR OMA; RVFFVSW; -.
DR OrthoDB; 5010334at2759; -.
DR Proteomes; UP000006310; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 2.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR11003:SF291; POTASSIUM CHANNEL SUBFAMILY K MEMBER 18; 1.
DR PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR Pfam; PF07885; Ion_trans_2; 2.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006310};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 39..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 206..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 259..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..420
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 212..284
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 347..420
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT REGION 683..768
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 709..752
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 768 AA; 85973 MW; 4EF3D319052D77E7 CRC64;
MAKNLEHQNS QVMRALRASL KFRNNRVSII NSDPSSRAFV FWFMISCYFP LIAACLGPIA
NTISIACVVD KWREWGVSRN KNGDITANQV RDPTDVFVLN IISLVIGFVS NVVLLFHFAR
KLSYLKSQLI NITGWTAAGV LLLVDVIVCG TRDVKPRYQK TIGFWYACFT SGLYLGCALV
LSIHYIGYVL KKYPATFNLL PNERSIMVFT VMFSLWLIWG AAMFSGLLGI SFGNALYFCT
VSLLTIGLGD ILADNVSSKI MILVFSISGV IILGLIVYMT RSIIQKSSGP VWYFHRLERK
RSKIWKKVCA GELKLTDEES FDLMTKVKRV SKIRENIFSV TTTILIFSCF WLLGACVFHF
CEGWSYFNCI YFCFLCLLTI GYGSDYAPET GAGRAFFVLW SIGAVPLMGA ILSTVGDLLF
DMSDSIDVKL GEKFDSTVKS IVINGKGAIT SLNFTRGTLV DTEAENQTGI EDKPLTESQR
KKVENLDIVK EYNSSLEDND ESDRSFSVIP SLDGFSEYDL TLERMASNQS VELNKLKELR
LLLKSLSRLH KISVEDKNFK LNYKQWKNLH SLHTHEEELE GYEKTNFWVS DLSPLKYPLN
EAHFAFLRLS EAVDKLVSSL IEKDEAKVDS LRPVMSNLLS RHGSIVSRTK SNGSTHFVGD
NDRARYNSVS VAKSHDDVNA RLRSDNIRSR KATGTVQLQT DRESGDTREN YGGSTPSILS
SNVSSKLVDP SPGHSNDGDT RSYLTDVADS ESDNEANPAA GHFDVKTI
//
