ID J7RL85_KAZNA Unreviewed; 661 AA.
AC J7RL85;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=RNase III domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=KNAG0D05350 {ECO:0000313|EMBL:CCK70273.1};
GN OrderedLocusNames=KNAG_0D05350 {ECO:0000313|EMBL:CCK70273.1};
OS Kazachstania naganishii (strain ATCC MYA-139 / BCRC 22969 / CBS 8797 / KCTC
OS 17520 / NBRC 10181 / NCYC 3082 / Yp74L-3) (Yeast) (Saccharomyces
OS naganishii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kazachstania.
OX NCBI_TaxID=1071383 {ECO:0000313|EMBL:CCK70273.1, ECO:0000313|Proteomes:UP000006310};
RN [1] {ECO:0000313|EMBL:CCK70273.1, ECO:0000313|Proteomes:UP000006310}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520
RC / NBRC 10181 / NCYC 3082 {ECO:0000313|Proteomes:UP000006310};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
RN [2] {ECO:0000313|Proteomes:UP000006310}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520
RC / NBRC 10181 / NCYC 3082 {ECO:0000313|Proteomes:UP000006310};
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Genome sequence of Kazachstania naganishii.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; HE978317; CCK70273.1; -; Genomic_DNA.
DR AlphaFoldDB; J7RL85; -.
DR STRING; 1071383.J7RL85; -.
DR eggNOG; KOG1817; Eukaryota.
DR HOGENOM; CLU_018453_0_0_1; -.
DR OMA; PYANEGA; -.
DR OrthoDB; 342391at2759; -.
DR Proteomes; UP000006310; Chromosome 4.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004525; F:ribonuclease III activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd10845; DSRM_RNAse_III_family; 1.
DR CDD; cd00593; RIBOc; 1.
DR Gene3D; 1.20.1270.260; -; 1.
DR Gene3D; 3.30.160.20; -; 2.
DR Gene3D; 1.10.1520.10; Ribonuclease III domain; 1.
DR InterPro; IPR048504; Dicers-like_N.
DR InterPro; IPR048505; Dicers-like_N_sf.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR000999; RNase_III_dom.
DR InterPro; IPR036389; RNase_III_sf.
DR PANTHER; PTHR14950; DICER-RELATED; 1.
DR PANTHER; PTHR14950:SF37; ENDORIBONUCLEASE DICER; 1.
DR Pfam; PF20860; Dicers_N; 1.
DR Pfam; PF00035; dsrm; 2.
DR Pfam; PF00636; Ribonuclease_3; 1.
DR SMART; SM00358; DSRM; 2.
DR SMART; SM00535; RIBOc; 1.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 2.
DR SUPFAM; SSF69065; RNase III domain-like; 1.
DR PROSITE; PS50137; DS_RBD; 2.
DR PROSITE; PS00517; RNASE_3_1; 1.
DR PROSITE; PS50142; RNASE_3_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006310};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00266}.
FT DOMAIN 94..243
FT /note="RNase III"
FT /evidence="ECO:0000259|PROSITE:PS50142"
FT DOMAIN 277..342
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 590..656
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 357..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 393..421
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 661 AA; 72431 MW; 81D2BD1E3EAF3002 CRC64;
MSAVVPPDNA SGAALLAAGG ARSPADNVRR FFKLQSACAA LLEAARTVYE CSFPTGELKT
MGSKSGDPLS EAIAASPAAQ IGSYLVENRE ALDLEHMFEV FRFDANESPV HCFIQYPVVS
DAQLENLAFV HRSFPNMNVH LSAAERTVMS NERLEFLGDS WLGAIVAYFL YKKYPYANEG
ALSRMKSAIV NNNNLEKICS RLGFKQRLRA NVPGYKMKIR DSFSKYHADV VEAYIGAFVV
DRFKTEFQEL ADWIEKLSEE QLQLFGPEML NTPLNKNAKG ELAELLQFNK TGGKLTYRRM
TQTSPFKVQA LLGNIVLSEG SGANVKDAER RAAMAALDKP ELIAKYSLFD IVPNESEENP
VEQLPDSNMN PAYVKYGSSD GSGHHVESSS NEEDSSSEES SSSEESSSTE ESSDDEESVL
DDQPPVVPIQ ETKSPLDMEQ FKKDLMSKMD VIVSSIFTEA LKNSSVQDTN GKPSNNVPGI
DTDGFSAVPN HSQSGVANTN LPRTEKNYLD TGVNAAKPKM PPLKPMPKLV SPFDKQQATT
TGLPMKLQTH QPKVANMSPP LPSPMQTLNQ YNTENKVGPQ ERPNAFGPLM AARDLYTLLN
QHHRFPDYKI LPTADGGFKA RCFVKGTAIM LGEGTGRTKK EAKQVAAAKA LKGAALRSIR
T
//
