ID J7S198_KAZNA Unreviewed; 1329 AA.
AC J7S198;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=C2 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=KNAG0G03050 {ECO:0000313|EMBL:CCK71362.1};
GN OrderedLocusNames=KNAG_0G03050 {ECO:0000313|EMBL:CCK71362.1};
OS Kazachstania naganishii (strain ATCC MYA-139 / BCRC 22969 / CBS 8797 / KCTC
OS 17520 / NBRC 10181 / NCYC 3082 / Yp74L-3) (Yeast) (Saccharomyces
OS naganishii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kazachstania.
OX NCBI_TaxID=1071383 {ECO:0000313|EMBL:CCK71362.1, ECO:0000313|Proteomes:UP000006310};
RN [1] {ECO:0000313|EMBL:CCK71362.1, ECO:0000313|Proteomes:UP000006310}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520
RC / NBRC 10181 / NCYC 3082 {ECO:0000313|Proteomes:UP000006310};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
RN [2] {ECO:0000313|Proteomes:UP000006310}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520
RC / NBRC 10181 / NCYC 3082 {ECO:0000313|Proteomes:UP000006310};
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Genome sequence of Kazachstania naganishii.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; HE978320; CCK71362.1; -; Genomic_DNA.
DR STRING; 1071383.J7S198; -.
DR eggNOG; ENOG502QQWJ; Eukaryota.
DR HOGENOM; CLU_003023_1_0_1; -.
DR OMA; VLKSPKW; -.
DR OrthoDB; 1984726at2759; -.
DR Proteomes; UP000006310; Chromosome 7.
DR Gene3D; 1.10.357.50; -; 1.
DR Gene3D; 1.20.58.1100; -; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR014770; Munc13_1.
DR InterPro; IPR014772; Munc13_dom-2.
DR PANTHER; PTHR47263; ADENYLATE CYCLASE ACTIVATION PROTEIN GIT1; 1.
DR PANTHER; PTHR47263:SF1; C2 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G02350); 1.
DR Pfam; PF00168; C2; 1.
DR SMART; SM00239; C2; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS51258; MHD1; 1.
DR PROSITE; PS51259; MHD2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006310}.
FT DOMAIN 658..776
FT /note="MHD1"
FT /evidence="ECO:0000259|PROSITE:PS51258"
FT DOMAIN 871..999
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 1077..1214
FT /note="MHD2"
FT /evidence="ECO:0000259|PROSITE:PS51259"
FT REGION 53..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1329 AA; 151918 MW; B1744010B55F729B CRC64;
MNRISSLKSG DASDESLGSL SISEYSPKVE LESVYLYTLR LLVLEYINKP QFKQNDRNRQ
SPPTPPSSSS SSSSYSSLHS SRWSLSSSPL EDSGRSVSLG LGKSLFSNGQ FSRSTNKTNY
SEHIRIMTTL KQRLATYLYD VTIGRKKVTN ATFRRCLLKF NNDTFMNSSL STTLENMSNV
EELIVYFTKS ANNELSKVVV GDIQKELFKQ VSKFVGLLQS LLPTNTPASF INKLTACADR
MKPTKPSLKQ KLFSNEKRRS ATPVMYETSD SSSMSAVRKP VAALHVAPSF KLDDIPYSNY
FSEIFNTDSI KVQQDVIKVM KESTNFTFSR ELDEYSFQLQ SDGGFLFLSD FRTEEEYNSW
KILETKEIEL LKNEFRTIGR APSVPNSKNL IMPSDPRSTF VMLMNLIIKK ECSTNMSSME
FTPGALYFMN TAARYWRVDF PSTLAALFYT ASNISVLHSE EINLALTEGL FTFIKSTILH
SDAIVDTRDW NEMDRRQWNA NLFYTSEQCV NSLDNLLTGL YATTKPKFSP ILVFYFEYVS
ADPSFQEHLP TIEKRIVKRL RRTIFKTSEK YYKSLIMELP KDETLEFKHI QNIAELIVRQ
LNTIQKRYTK PLLDKVNISF ECATMLTTAM AIDGPNMIKK IERVLESKKK DVPPVDALEL
YSTFRELRDI YRQVQLKEKF PFNLERAFGK YLKRFAKNIA LKISEVFRNS IKTETWEKIN
DDVRYSKSVL DIFKMANESL NIFKSFDWDI NYRFAEAVVI VLKAFSDGIQ LYCDMAVKLV
QKSLRYSSAS SYGFEDRGSS TNESEKRKSK WDFHEMKKAV RSSSSSAIPQ PYKYKTETCV
ILNDVDTMIA HLEELENIVD FSELSKVITE HNAVKQKTTG ETLKDGVYQL YTIRIKSASD
IKGYGSNGLS NSSVSLINSR EKSEIGETKV VPKSNNPEWD EEFELQLKRD EKCTLLLNVW
HHPTGNFMSL TGADLCGRVS LVLDPKEFAD DGFPNPKTLI LDTRGELNME IALETERMDP
LFCIGRSYRT LSRARDKILE LVVNKFTPFV SFVFSREVLK SICGGHGTRK PSDEEIYDAI
VPLFDYLNAN LNVLGQELSH GLLFMVMLKG WLFIIKAADI MLLPQVDIAK HRLANARKSL
WSIGSSNSVS GYGRALTEYE IDCIFKWLDA LCVDFFYNQG EGPPLKALQN TEYQTLLLIP
SFYKKSALEL KSEVKRLNPL YFQNIAELTS GSNVAVSRRF TTVERRKTIM GNSSKGKRKQ
LQEELQKADT DSLQQSLSTL NIILRVLITK GETDYVYRQL HERKQKMKRI NVASSADKVS
KGQKINYRS
//
