ID J7S3U0_KAZNA Unreviewed; 365 AA.
AC J7S3U0;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CCK68904.1};
GN Name=KNAG0B04690 {ECO:0000313|EMBL:CCK68904.1};
GN OrderedLocusNames=KNAG_0B04690 {ECO:0000313|EMBL:CCK68904.1};
OS Kazachstania naganishii (strain ATCC MYA-139 / BCRC 22969 / CBS 8797 / KCTC
OS 17520 / NBRC 10181 / NCYC 3082 / Yp74L-3) (Yeast) (Saccharomyces
OS naganishii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kazachstania.
OX NCBI_TaxID=1071383 {ECO:0000313|EMBL:CCK68904.1, ECO:0000313|Proteomes:UP000006310};
RN [1] {ECO:0000313|EMBL:CCK68904.1, ECO:0000313|Proteomes:UP000006310}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520
RC / NBRC 10181 / NCYC 3082 {ECO:0000313|Proteomes:UP000006310};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
RN [2] {ECO:0000313|Proteomes:UP000006310}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520
RC / NBRC 10181 / NCYC 3082 {ECO:0000313|Proteomes:UP000006310};
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Genome sequence of Kazachstania naganishii.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the RRP4 family.
CC {ECO:0000256|ARBA:ARBA00009155}.
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DR EMBL; HE978315; CCK68904.1; -; Genomic_DNA.
DR AlphaFoldDB; J7S3U0; -.
DR STRING; 1071383.J7S3U0; -.
DR eggNOG; KOG3013; Eukaryota.
DR HOGENOM; CLU_034114_3_0_1; -.
DR OMA; GVNGFIW; -.
DR OrthoDB; 5472588at2759; -.
DR Proteomes; UP000006310; Chromosome 2.
DR GO; GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR CDD; cd22525; KH-I_Rrp4_eukar; 1.
DR CDD; cd05789; S1_Rrp4; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR025721; Exosome_cplx_N_dom.
DR InterPro; IPR026699; Exosome_RNA_bind1/RRP40/RRP4.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR048565; RRP4_S1.
DR PANTHER; PTHR21321:SF4; EXOSOME COMPLEX COMPONENT RRP4; 1.
DR PANTHER; PTHR21321; PNAS-3 RELATED; 1.
DR Pfam; PF14382; ECR1_N; 1.
DR Pfam; PF15985; KH_6; 1.
DR Pfam; PF21266; RRP4_S1; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF110324; Ribosomal L27 protein-like; 1.
PE 3: Inferred from homology;
KW Exosome {ECO:0000256|ARBA:ARBA00022835};
KW Reference proteome {ECO:0000313|Proteomes:UP000006310};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552}.
FT DOMAIN 52..89
FT /note="Exosome complex component N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14382"
FT DOMAIN 101..173
FT /note="RRP4 S1"
FT /evidence="ECO:0000259|Pfam:PF21266"
FT DOMAIN 195..236
FT /note="K Homology"
FT /evidence="ECO:0000259|Pfam:PF15985"
FT REGION 25..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 365 AA; 39757 MW; 0F8C0ED3BB90F109 CRC64;
MSEVITVVKR KGVFENDAAF NGDRIDLSSE DEMMSDADEE NSISRRDTDS PIVTPGELIT
DDPVWMRGHG TYFLDNVTYS SVVGTVSKVN KLLSVVPLKG RYAPETGDHV VGRISEVGNK
RWKVDIGAKQ HAVLMLGSVN LPGGILRRKS ENDELQMRSF LKEGDLLNAE VQSLFQDGSA
SLHTRSLKYG KLRDGQFCGV ASSLIVKSKN HTHNLPGNVT VVLGVNGYIW LRKTSQMDLA
RDLNSVGAAG GASTPKGTNG PTGAVSLNPT TNVSITRLEE ESSWQIYSDK NDPNISDSIK
LTITRYANVI KALAFCEIGI TQERIISAYE SSMVYRNVGS LIEREVMESL GADVINGEKM
RGTGV
//
