ID J7S5U8_KAZNA Unreviewed; 1257 AA.
AC J7S5U8;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Potassium transport protein {ECO:0000256|PIRNR:PIRNR002450};
GN Name=KNAG0C02700 {ECO:0000313|EMBL:CCK69381.1};
GN OrderedLocusNames=KNAG_0C02700 {ECO:0000313|EMBL:CCK69381.1};
OS Kazachstania naganishii (strain ATCC MYA-139 / BCRC 22969 / CBS 8797 / KCTC
OS 17520 / NBRC 10181 / NCYC 3082 / Yp74L-3) (Yeast) (Saccharomyces
OS naganishii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kazachstania.
OX NCBI_TaxID=1071383 {ECO:0000313|EMBL:CCK69381.1, ECO:0000313|Proteomes:UP000006310};
RN [1] {ECO:0000313|EMBL:CCK69381.1, ECO:0000313|Proteomes:UP000006310}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520
RC / NBRC 10181 / NCYC 3082 {ECO:0000313|Proteomes:UP000006310};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
RN [2] {ECO:0000313|Proteomes:UP000006310}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520
RC / NBRC 10181 / NCYC 3082 {ECO:0000313|Proteomes:UP000006310};
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Genome sequence of Kazachstania naganishii.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TrkH potassium transport family.
CC {ECO:0000256|ARBA:ARBA00009137, ECO:0000256|PIRNR:PIRNR002450}.
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DR EMBL; HE978316; CCK69381.1; -; Genomic_DNA.
DR AlphaFoldDB; J7S5U8; -.
DR STRING; 1071383.J7S5U8; -.
DR eggNOG; KOG1341; Eukaryota.
DR HOGENOM; CLU_005947_0_0_1; -.
DR OMA; MVNRDEQ; -.
DR OrthoDB; 11415at2759; -.
DR Proteomes; UP000006310; Chromosome 3.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0030007; P:intracellular potassium ion homeostasis; IEA:UniProtKB-UniRule.
DR InterPro; IPR003445; Cat_transpt.
DR InterPro; IPR004773; K/Na_transp_Trk/HKT.
DR InterPro; IPR015958; Trk_fungi.
DR NCBIfam; TIGR00934; 2a38euk; 1.
DR PANTHER; PTHR31064:SF30; HIGH-AFFINITY POTASSIUM TRANSPORT PROTEIN-RELATED; 1.
DR PANTHER; PTHR31064; POTASSIUM TRANSPORT PROTEIN DDB_G0292412-RELATED; 1.
DR Pfam; PF02386; TrkH; 1.
DR PIRSF; PIRSF002450; K+_transpter_TRK; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR002450};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR002450};
KW Potassium {ECO:0000256|ARBA:ARBA00022958, ECO:0000256|PIRNR:PIRNR002450};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538,
KW ECO:0000256|PIRNR:PIRNR002450};
KW Reference proteome {ECO:0000313|Proteomes:UP000006310};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|PIRNR:PIRNR002450};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|PIRNR:PIRNR002450};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR002450}.
FT TRANSMEM 50..70
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 108..132
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 803..827
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 839..857
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 869..898
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 932..952
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 997..1014
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 1116..1138
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT REGION 160..268
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 305..389
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 409..520
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 571..613
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 659..714
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1036..1067
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1230..1257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..226
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..268
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 306..321
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 333..374
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 409..429
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 440..458
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 459..488
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 571..587
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 698..714
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1044..1067
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1257 AA; 143701 MW; B16547561FC8475E CRC64;
MAFGRTSTSV STSSWFVENY KKTVGHKFRD FIASCGHYIK PFKKYFLPNF IAVHYFYIIS
LTILGSILMY PVHNFRYIDI LFLACGATTQ GGLNTVNVND LTLYQQLIIY LLCCISTPIA
IHGCLAFVRL YWFERYFDGI KDRSKRNFKM RRTRTILQRE MTKRSHQATH TFNARTYSSV
QTQRSNAVQG PNAADPDFQE KLFSGRKVNR DEQSFHSEES QDTNLPDRMK IDNSSGSSTG
DGTHYTETSS SSTNHAGERF ASRRNSTDIT PVDMYRSIMM FRGQHQDQNE EGEGPALVIK
GRNVASDIQR PKHKPLLQDI QSVDEGDESS TEETSQILRP KSLSSGINSQ EDRPTLGETH
VGGQDSNSIY TDSDDMNHTV DDEVEPPNAS AISSQELELF EPGSDVNFSN RSINNHSVSD
SNISSENVRD YRGSDYDDDN TGDDGNDEIS DDEAESLDDS LSSGSQTDAN TPLETGPLEY
PDNTQHISFS NDDETRRQRG VTVNQRNRGK LEDSSVRPKE GQSIQFNITA RPKRRYQIQG
AKKARNPYYH TKKRPAKRLL LKQLKKGKRL REQLQGRLSR ATTDKDDYPD NFSAPSTDPR
PRAEILENKG NNDMEEYFAD DETDEDIPYD ISPEELNRLS QTPDFQKMIY KNWKAKHRKT
GKLGKASRTL EKTLTSGSHS NFPRPRRNHH LSNDFHKNKP NNGDAGNLSS DDSYGSVLDS
ERGTDYYNYI DTEDQAQHGN HFEYNFDQNN LNLPLNRTMS TNYLSWQPTI GRNSTFVGLS
KSQRDELGGV EYRAIKLLCK ILLCYYFGFH VMAFVMMVPW ICVKKYYIHI VRSDGVSPAW
WGFFTSMSAF SDLGLTVTPD SMTSFNKAIY PQIVMMWFII IGNTGFPILL RCIIWVMFKT
APELSQTKES LGFLLDHPRR CFTLLFPEAA TWWLLLTLLF LNITDWILFI ILDMGSAVLK
PLSRGLRVLN GLFQAVSTRT AGFSIVDLSK LHPAIQVSYM LMMYVSVLPV AISIRRTNVY
EERSLGMYGK IEEHDDEDED VDSSDTETKT KKSKKRKNRN NLEEDDEKKD HVSTKSFIGA
HLRKQLSFDL WFLFLGLFVI CLCENSKIQD TTRPNFNVFS ILFEIVSAYG TIGLSLGYPE
TNQSFSAQFT SLSKLVIILM LIRGRCRGLP YSLDRAIILP SDRLEHIDHM EDLKLRKNHG
RAETIDPVTE YVKHSTGVFR KKLERFNTHG HIPSHIGPSD EFEMTNQNRR RMEHQTM
//
