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Database: UniProt
Entry: J7SB08_NAUDC
LinkDB: J7SB08_NAUDC
Original site: J7SB08_NAUDC 
ID   J7SB08_NAUDC            Unreviewed;       890 AA.
AC   J7SB08;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   07-JUN-2017, entry version 27.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   Name=NDAI0G04680 {ECO:0000313|EMBL:CCK73453.1};
GN   OrderedLocusNames=NDAI_0G04680 {ECO:0000313|EMBL:CCK73453.1};
OS   Naumovozyma dairenensis (strain ATCC 10597 / BCRC 20456 / CBS 421 /
OS   NBRC 0211 / NRRL Y-12639) (Saccharomyces dairenensis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Naumovozyma.
OX   NCBI_TaxID=1071378 {ECO:0000313|EMBL:CCK73453.1, ECO:0000313|Proteomes:UP000000689};
RN   [1] {ECO:0000313|EMBL:CCK73453.1, ECO:0000313|Proteomes:UP000000689}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10597 / BCRC 20456 / CBS 421 / NBRC 0211 / NRRL Y-12639
RC   {ECO:0000313|Proteomes:UP000000689};
RX   PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA   Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S.,
RA   Byrne K.P., Wolfe K.H.;
RT   "Evolutionary erosion of yeast sex chromosomes by mating-type
RT   switching accidents.";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
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DR   EMBL; HE580273; CCK73453.1; -; Genomic_DNA.
DR   RefSeq; XP_003980129.1; XM_003980080.1.
DR   STRING; 1071378.XP_003980129.1; -.
DR   EnsemblFungi; CCK73453; CCK73453; NDAI_0G04680.
DR   GeneID; 13926932; -.
DR   KEGG; ndi:NDAI_0G04680; -.
DR   eggNOG; KOG2189; Eukaryota.
DR   eggNOG; COG1269; LUCA.
DR   KO; K02154; -.
DR   OrthoDB; EOG092C0YCY; -.
DR   Proteomes; UP000000689; Chromosome 7.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:EnsemblFungi.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005770; C:late endosome; IEA:EnsemblFungi.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:EnsemblFungi.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:EnsemblFungi.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   GO; GO:0007035; P:vacuolar acidification; IEA:EnsemblFungi.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000689};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000689};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    466    490       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    511    528       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    588    608       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    620    640       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    680    700       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    831    851       Helical. {ECO:0000256|RuleBase:RU361189}.
SQ   SEQUENCE   890 AA;  101167 MW;  1AC1374296E6DCDD CRC64;
     MTYVQLYIPL EISRETVCLL GNLGNIMFRD LNKDLTDFQR SYVSQLRKFD DVERLLNYLK
     ETADKHSDAT WKYILHVDEQ GNDIISPSLT TVVQSLGSYS QDSINNLIGD VTGSETRVRQ
     LDDSLNGLKE KLNGLIENRC VIIQCSKYLE RNPNTIGRST SDSNSTANAN ENDFIFSDEE
     VDAVSNTLSD TFSFDDDDNN NNDTNNDNNS GQAPMNARLT TDETTSFEEF GFLETGYHHR
     YMIAGSINRT KVELLNRILW RLLRGNLFFQ NFPIDIPLLE GKEKVEKDSF IVFTHGDLLL
     SKVKRVIESL DGKVVTLERR PHDAVEKLNS EISDIQQVVH TTEQTLHTEL LVVNDQLPTW
     NAVVKREKYI HATLNLFKQE VQGLLAEGWI PSSDVDELSD SLKDHSESLG SEYGTVVNII
     HTNKNPPTFH RTNKFTQAFQ SIVDAYATAT YKEVNPGLAT IVTFPFMFAI MFGDAGHGMI
     VLLIALYFIL NEKKFEAMQK DEILDMVYSG RYMICLMGAF SIYTGIIYND IFSRPMTFFK
     SGWEWPSTFK KGDSIEAGKV GVYSFGIDYA WHGAENGLLF MNSYKMKLSI LMGFIHMTYS
     YAFAYINFRY KNSRVDIIGN FIPGLIFMQS IFGYLSWAIV YKWSKDWIKD GKPAPGLLNM
     LINMFLSPGT IDEPLYRGQA VLQSILLIAA LVCVPWLLLY KPLTLRKQNK GYRRLQSSNA
     DNPPMLNIEI QDPTLDSSNI NNSNMTITDY GDDTIADDDN EEEEAFDFGD VMIHQVIHTI
     EFCLNCISHT ASYLRLWALS LAHAQLSSVL WDMTIGISFS SNNSGSTLSV IKVIFLFGMW
     FVLSVCILVF MEGTSAMLHA LRLHWVEAMS KFFEGEGYPY EPFSFDNLIE
//
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