ID J7TFJ8_STRSL Unreviewed; 337 AA.
AC J7TFJ8;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Diacylglycerol kinase family protein {ECO:0000313|EMBL:EJO15526.1};
GN ORFNames=RSSL_00397 {ECO:0000313|EMBL:EJO15526.1};
OS Streptococcus salivarius K12.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=1200793 {ECO:0000313|EMBL:EJO15526.1, ECO:0000313|Proteomes:UP000006983};
RN [1] {ECO:0000313|EMBL:EJO15526.1, ECO:0000313|Proteomes:UP000006983}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Streptococcus salivarius K12
RC {ECO:0000313|Proteomes:UP000006983};
RX PubMed=23045482; DOI=10.1128/JB.01268-12;
RA Barretto C., Alvarez-Martin P., Foata F., Renault P., Berger B.;
RT "Genome Sequence of the Lantibiotic Bacteriocin Producer Streptococcus
RT salivarius Strain K12.";
RL J. Bacteriol. 194:5959-5960(2012).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the diacylglycerol/lipid kinase family.
CC {ECO:0000256|ARBA:ARBA00005983}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJO15526.1}.
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DR EMBL; ALIF01000006; EJO15526.1; -; Genomic_DNA.
DR RefSeq; WP_002891548.1; NZ_ALIF01000006.1.
DR AlphaFoldDB; J7TFJ8; -.
DR PATRIC; fig|1200793.3.peg.1516; -.
DR Proteomes; UP000006983; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 2.60.200.40; -; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR005218; Diacylglycerol/lipid_kinase.
DR InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR InterPro; IPR045540; YegS/DAGK_C.
DR NCBIfam; TIGR00147; YegS/Rv2252/BmrU family lipid kinase; 1.
DR PANTHER; PTHR12358:SF115; DIACYLGLYCEROL KINASE; 1.
DR PANTHER; PTHR12358; SPHINGOSINE KINASE; 1.
DR Pfam; PF00781; DAGK_cat; 1.
DR Pfam; PF19279; YegS_C; 1.
DR SMART; SM00046; DAGKc; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR PROSITE; PS50146; DAGK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EJO15526.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..135
FT /note="DAGKc"
FT /evidence="ECO:0000259|PROSITE:PS50146"
SQ SEQUENCE 337 AA; 36802 MW; C41CB646812327C9 CRC64;
MKQKRARLIY NPTSGQEIMK KNVAEVLDIL EGAGFEASAF QTTPDENSAK NEATRAAKAG
FDLVIAAGGD GTINEVVSGI APLKKRPQMA VIPTGTTNDF ARALKIPRGN PVEAAKVIAK
NQTLLMDIGR AYDDKYFINI AAAGSFTELT YSVPSRLKTV LGYLAYLVKG AELLPQVKKV
PVRITHDEGV FEGGLSMIFV ALTNSVGGFE TIAPDAKLDD GKFTLIMVKT ANLFELVDLI
RQILQGGKHI YDKRISYIKT SSLYIEPLSD DRMMINLDGE YGGDAPIHLQ NLKNHIEFYA
NIDEISDDAI TLPDTDELAL EAIAQKFSTE AEKIEND
//
