ID J7TR83_MORMO Unreviewed; 392 AA.
AC J7TR83;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Membrane fusion component of tripartite multidrug resistance system {ECO:0000313|EMBL:AGG30365.1};
GN ORFNames=MU9_1319 {ECO:0000313|EMBL:AGG30365.1};
OS Morganella morganii subsp. morganii KT.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Morganella.
OX NCBI_TaxID=1124991 {ECO:0000313|EMBL:AGG30365.1, ECO:0000313|Proteomes:UP000011834};
RN [1] {ECO:0000313|EMBL:AGG30365.1, ECO:0000313|Proteomes:UP000011834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KT {ECO:0000313|EMBL:AGG30365.1,
RC ECO:0000313|Proteomes:UP000011834};
RX PubMed=23282187;
RA Chen Y.T., Peng H.L., Shia W.C., Hsu F.R., Ken C.F., Tsao Y.M., Chen C.H.,
RA Liu C.E., Hsieh M.F., Chen H.C., Tang C.Y., Ku T.H.;
RT "Whole-genome sequencing and identification of Morganella morganii KT
RT pathogenicity-related genes.";
RL BMC Genomics 13:S4-S4(2012).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP004345; AGG30365.1; -; Genomic_DNA.
DR RefSeq; WP_004235565.1; NC_020418.1.
DR AlphaFoldDB; J7TR83; -.
DR GeneID; 69679728; -.
DR KEGG; mmk:MU9_1319; -.
DR eggNOG; COG1566; Bacteria.
DR HOGENOM; CLU_018816_15_0_6; -.
DR Proteomes; UP000011834; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR005694; MFP_proteobact.
DR NCBIfam; TIGR00998; 8a0101; 1.
DR PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR PANTHER; PTHR30386:SF19; MULTIDRUG EXPORT PROTEIN EMRA-RELATED; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 2.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022519};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011834};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 37..348
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
FT DOMAIN 212..291
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 392 AA; 42837 MW; 102242539F4F80BF CRC64;
MSVSEETQAV QPPVRNKKRQ RRNALMLLTL LFVLLGAAYT VYWFMVLRHH ESTDNAYVTG
NQVIVMSQVP GSVTTVSVDN TDYVTAGTLL VQLDKRDAGL ALEKAQVALA NSVRQTHQQM
INSRQLLAGI EVRRSELTRL QNDLRRREVL GAQNVIGKEE LQHAREAVVS AKAQLDVATE
QFNANKAVIL DTPLSEQPAV KQAATEVRNA WLALERTDIR SPVDGYVSRR SVQVGAQITP
ATPLMAVVPA TGMWIDANFK ETQLSAMRIG QPAKVVTDFY GDKVVFTGTV TGLDMGTGSA
FSLLPAQNAS GNWIKVVQRL PVRIALDPAQ LEKYPLRIGL SGDVTVDTQN TDGPVLSKSV
RTDPAYHTSA LSIDMQPADQ MIAEIISRNA GQ
//
