ID J8DQQ4_BACCE Unreviewed; 892 AA.
AC J8DQQ4;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Diguanylate cyclase (GGDEF) domain-containing protein {ECO:0000313|EMBL:EJQ87081.1};
GN ORFNames=IGC_00204 {ECO:0000313|EMBL:EJQ87081.1};
OS Bacillus cereus HuA4-10.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC Bacillus cereus group.
OX NCBI_TaxID=1053206 {ECO:0000313|EMBL:EJQ87081.1, ECO:0000313|Proteomes:UP000006977};
RN [1] {ECO:0000313|EMBL:EJQ87081.1, ECO:0000313|Proteomes:UP000006977}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HuA4-10 {ECO:0000313|EMBL:EJQ87081.1,
RC ECO:0000313|Proteomes:UP000006977};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Feldgarden M., Van der Auwera G.A., Mahillon J., Duprez V., Timmery S.,
RA Mattelet C., Dierick K., Sun M., Yu Z., Zhu L., Hu X., Shank E.B.,
RA Swiecicka I., Hansen B.M., Andrup L., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Chapman S.B., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Larimer J., McCowen C., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Bacillus cereus HuA4-10.";
RL Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJQ87081.1}.
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DR EMBL; AHEA01000003; EJQ87081.1; -; Genomic_DNA.
DR RefSeq; WP_002144699.1; NZ_JH792148.1.
DR AlphaFoldDB; J8DQQ4; -.
DR PATRIC; fig|1053206.3.peg.208; -.
DR HOGENOM; CLU_000445_129_2_9; -.
DR Proteomes; UP000006977; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR025152; DUF4084.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF13321; DUF4084; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00989; PAS; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 31..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 64..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 100..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 131..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 339..409
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 411..462
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 494..627
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 636..890
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 892 AA; 102883 MW; 7963A6F63F481927 CRC64;
MINQKKYVQF VMMYIIIFSL WIFLIPKDLN IKEIGILFLF CFAALFSCYC LYKAIKKMKR
GDKLFWVLLL CTCLCGLTME ITLFLHSLSI YDQVIFSYRA LPFFIVQYIL LFSGFAIKFI
KHYSIRGLAQ FSFDSIFIVI MNIYFTLTFI LDISSFRMLT TDTWVLIGYF IAQSLVIYAV
ISLYRREQYS SSRIALIVGF TIILVYGYIH LFQLRLGMET SSEVSYLIHT ASILLIGLSS
ILYILDKPMQ HETKTKYYRF DYVRFILPYF SIIITFSFIV IQPWDDKFML IGLVLSLILL
FLRQLYMWKD NQVLIDTYEQ LTTQLEGKVE EGASALSKSE QRYTSLFEDH PDAVFSLNMN
GIFQQSNKAC ESLFTAYYCE VTSYSLLHFI DPKDHKLLKK SLQITKEGGP QTLEVRTKEK
EGYYYYLHIT LIPTFINKEV VGMFGIARDI TTLYEKQKQV EHLAFHDALT GLPNRRKFEK
DLKTILNTAQ NNTNDVAVMF LDLDRFKKIN DRLGHAVGDL LLIEVAKRLR GCLRSKDIVA
RQGGDEFTIL LPDMYSEKSA SFIAEQILTI LNKPYFIKDE ELSVTPSIGI AMYPDYGTDV
TELMKNADMA MYRAKANGKN RFVFFSKEMS IAQNEIHFLE GELSKALQQN EFFLEYQPQV
NTKTKQIIGF EALIRWKHPK LGIVSPAQFI PLAEETGFII ELGNWILRTA CLEAKKWHNQ
GFSNLKVGVN LSVVQFNHAD LISTISKVLE ETELKPEALD IEITESIAIN QNHSVIAKLE
ELQNLGIQIS IDDFGTGYSS LAYLTKYPIN TLKIAREFIC GITNSPLEEA IIASIITLSK
ELNLEVIAEG VETEEQWKFL HEQNCDHIQG FLFSKPVSSK DIWMLLHKKT TV
//
