ID J8LIC8_SACAR Unreviewed; 194 AA.
AC J8LIC8;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 03-MAY-2023, entry version 38.
DE RecName: Full=DNA replication complex GINS protein PSF3 {ECO:0000256|ARBA:ARBA00015140, ECO:0000256|RuleBase:RU367161};
GN ORFNames=SU7_3086 {ECO:0000313|EMBL:EJS41807.1};
OS Saccharomyces arboricola (strain H-6 / AS 2.3317 / CBS 10644) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=1160507 {ECO:0000313|EMBL:EJS41807.1, ECO:0000313|Proteomes:UP000006968};
RN [1] {ECO:0000313|EMBL:EJS41807.1, ECO:0000313|Proteomes:UP000006968}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H-6 / AS 2.3317 / CBS 10644
RC {ECO:0000313|Proteomes:UP000006968};
RX PubMed=23368932; DOI=10.1186/1471-2164-14-69;
RA Liti G., Nguyen Ba A.N., Blythe M., Mueller C.A., Bergstroem A.,
RA Cubillos F.A., Dafhnis-Calas F., Khoshraftar S., Malla S., Mehta N.,
RA Siow C.C., Warringer J., Moses A.M., Louis E.J., Nieduszynski C.A.;
RT "High quality de novo sequencing and assembly of the Saccharomyces
RT arboricolus genome.";
RL BMC Genomics 14:69-69(2013).
CC -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC DNA replication. {ECO:0000256|RuleBase:RU367161}.
CC -!- SUBUNIT: Component of the GINS complex which is a heterotetramer of
CC SLD5, PSF1, PSF2 and PSF3. {ECO:0000256|ARBA:ARBA00011352}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU367161}.
CC -!- SIMILARITY: Belongs to the GINS3/PSF3 family.
CC {ECO:0000256|ARBA:ARBA00006343, ECO:0000256|RuleBase:RU367161}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJS41807.1}.
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DR EMBL; ALIE01000177; EJS41807.1; -; Genomic_DNA.
DR AlphaFoldDB; J8LIC8; -.
DR HOGENOM; CLU_081646_0_1_1; -.
DR OrthoDB; 100586at2759; -.
DR Proteomes; UP000006968; Chromosome XV.
DR GO; GO:0000811; C:GINS complex; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR CDD; cd11713; GINS_A_psf3; 1.
DR CDD; cd21693; GINS_B_Psf3; 1.
DR Gene3D; 1.20.58.2050; -; 1.
DR InterPro; IPR021151; GINS_A.
DR InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR InterPro; IPR010492; GINS_Psf3.
DR InterPro; IPR038437; GINS_Psf3_sf.
DR PANTHER; PTHR22768:SF0; DNA REPLICATION COMPLEX GINS PROTEIN PSF3; 1.
DR PANTHER; PTHR22768; UNCHARACTERIZED; 1.
DR Pfam; PF05916; Sld5; 1.
DR SUPFAM; SSF158573; GINS helical bundle-like; 1.
DR SUPFAM; SSF160059; PriA/YqbF domain; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|RuleBase:RU367161};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU367161};
KW Reference proteome {ECO:0000313|Proteomes:UP000006968}.
FT DOMAIN 45..174
FT /note="GINS subunit"
FT /evidence="ECO:0000259|Pfam:PF05916"
SQ SEQUENCE 194 AA; 21862 MW; A6D36AC893512F9B CRC64;
MGYYDIDDVL ADGTDFPCKF QYDIPGLGYL ENNPGRPMAK NTKLNLPLWL ARILAIVGGD
EALVDEEPVP FVELLPPEMF AAKVMNAIKT DPVALDLHSI NSHFFSLAIK WITLFSEKEL
ANVVSELLLQ RAQELNHHAS SLTVDINANS TGKNSANTNI ATSTFLLKLD EMEKDIYKKS
HDSYKETKRW MFQK
//
