ID J8WAV5_ENTFC Unreviewed; 215 AA.
AC J8WAV5;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 03-MAY-2023, entry version 36.
DE SubName: Full=DNA-invertase {ECO:0000313|EMBL:EJV52038.1};
GN ORFNames=HMPREF1345_01464 {ECO:0000313|EMBL:EJV52038.1};
OS Enterococcus faecium TX1337RF.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=1134802 {ECO:0000313|EMBL:EJV52038.1, ECO:0000313|Proteomes:UP000003117};
RN [1] {ECO:0000313|EMBL:EJV52038.1, ECO:0000313|Proteomes:UP000003117}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TX1337RF {ECO:0000313|EMBL:EJV52038.1,
RC ECO:0000313|Proteomes:UP000003117};
RA Weinstock G., Sodergren E., Lobos E.A., Fulton L., Fulton R., Courtney L.,
RA Fronick C., O'Laughlin M., Godfrey J., Wilson R.M., Miner T., Farmer C.,
RA Delehaunty K., Cordes M., Minx P., Tomlinson C., Chen J., Wollam A.,
RA Pepin K.H., Bhonagiri V., Zhang X., Suruliraj S., Warren W., Mitreva M.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the site-specific recombinase resolvase family.
CC {ECO:0000256|ARBA:ARBA00009913}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJV52038.1}.
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DR EMBL; AMAA01000056; EJV52038.1; -; Genomic_DNA.
DR AlphaFoldDB; J8WAV5; -.
DR PATRIC; fig|1134802.3.peg.1374; -.
DR HOGENOM; CLU_010686_8_0_9; -.
DR Proteomes; UP000003117; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000150; F:DNA strand exchange activity; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR CDD; cd00569; HTH_Hin_like; 1.
DR CDD; cd03768; SR_ResInv; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.1390; Resolvase, N-terminal catalytic domain; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR006118; Recombinase_CS.
DR InterPro; IPR006119; Resolv_N.
DR InterPro; IPR036162; Resolvase-like_N_sf.
DR InterPro; IPR006120; Resolvase_HTH_dom.
DR PANTHER; PTHR30461; DNA-INVERTASE FROM LAMBDOID PROPHAGE; 1.
DR PANTHER; PTHR30461:SF22; SERINE RECOMBINASE PINE-RELATED; 1.
DR Pfam; PF02796; HTH_7; 1.
DR Pfam; PF00239; Resolvase; 1.
DR SMART; SM00857; Resolvase; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF53041; Resolvase-like; 1.
DR PROSITE; PS00397; RECOMBINASES_1; 1.
DR PROSITE; PS00398; RECOMBINASES_2; 1.
DR PROSITE; PS51736; RECOMBINASES_3; 1.
PE 3: Inferred from homology;
KW DNA integration {ECO:0000256|ARBA:ARBA00022908};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transposable element {ECO:0000256|ARBA:ARBA00022464}.
FT DOMAIN 22..157
FT /note="Resolvase/invertase-type recombinase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51736"
FT ACT_SITE 30
FT /note="O-(5'-phospho-DNA)-serine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606118-50,
FT ECO:0000256|PROSITE-ProRule:PRU10137"
SQ SEQUENCE 215 AA; 24312 MW; 845D4332A760FA61 CRC64;
MFIYTIGIKL CYNKINEGVI FLKIGYARVS TGLQNLDLQE DSLNKFGCEK IFTDHMSGAK
SNRPGLEMAI DFVRSGDTLV VWRLDRLGRN MEDLISIVNR LNERGVSFHS LQENITMDKS
SSTGQLMFHL FAAFAEFERN LILERSAAGR AAARARGRFG GRPEKLKAQD LELLKTLVDS
GTPIKTIAER WNVSRTTIYR YLDKMEGKDG KTNAH
//
