ID J9B997_WUCBA Unreviewed; 367 AA.
AC J9B997;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Pre-mRNA-splicing factor 38 {ECO:0000256|RuleBase:RU367025};
GN ORFNames=WUBG_05440 {ECO:0000313|EMBL:EJW83650.1};
OS Wuchereria bancrofti.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Wuchereria.
OX NCBI_TaxID=6293 {ECO:0000313|EMBL:EJW83650.1, ECO:0000313|Proteomes:UP000004810};
RN [1] {ECO:0000313|Proteomes:UP000004810}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NA {ECO:0000313|Proteomes:UP000004810};
RA Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Hepburn T.,
RA Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M.,
RA Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S.,
RA Walk T., White J., Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT "The Genome Sequence of Wuchereria bancrofti.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EJW83650.1}
RP NUCLEOTIDE SEQUENCE.
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Genome Sequencing Center for Infectious Disease;
RA Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A., Borenstein D., Chapman S.B., Chen Z., Engels R.,
RA Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.R.,
RA Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B., Mehta T.,
RA Park D., Pearson M., Richards J., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Haas B.,
RA Henn M.R., Nusbaum C., Birren B.;
RT "The Genome Sequence of Wuchereria bancrofti.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|WBParaSite:maker-PairedContig_1368-snap-gene-2.18-mRNA-1}
RP IDENTIFICATION.
RC STRAIN=pt0022
RC {ECO:0000313|WBParaSite:maker-PairedContig_1368-snap-gene-2.18-mRNA-1};
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- FUNCTION: Required for pre-mRNA splicing.
CC {ECO:0000256|RuleBase:RU367025}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU367025}.
CC -!- SIMILARITY: Belongs to the PRP38 family.
CC {ECO:0000256|ARBA:ARBA00006164, ECO:0000256|RuleBase:RU367025}.
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DR EMBL; ADBV01002072; EJW83650.1; -; Genomic_DNA.
DR STRING; 6293.J9B997; -.
DR WBParaSite; maker-PairedContig_1368-snap-gene-2.18-mRNA-1; maker-PairedContig_1368-snap-gene-2.18-mRNA-1; maker-PairedContig_1368-snap-gene-2.18.
DR Proteomes; UP000004810; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:UniProtKB-UniRule.
DR InterPro; IPR005037; PRP38.
DR PANTHER; PTHR23142:SF2; PRE-MRNA-SPLICING FACTOR 38B; 1.
DR PANTHER; PTHR23142; UNCHARACTERIZED; 1.
DR Pfam; PF03371; PRP38; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664,
KW ECO:0000256|RuleBase:RU367025};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187,
KW ECO:0000256|RuleBase:RU367025};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU367025};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728, ECO:0000256|RuleBase:RU367025}.
FT REGION 244..337
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..321
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 322..337
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 367 AA; 42819 MW; BD4AEFCD54C09EB0 CRC64;
MSAADGGAAA LLIAGLGTGG TDVMYEDDLT DNSIPDIQKI TKKNNILPLW GNTQTMNLNA
LVLENIIQCT YYKNYLAETT GFQQLTEEIY YSVKHLEPWE RGTRKTQGMT GMCGGVRGVG
AGGVVSTAFC LLYKLFTIRL SRKQLVSMIN NSDSPYIRGI GFMYIRFCQP PQDLWAWMEP
YLDDEEQIDP RSGGGDVMVM AQVVKMMLTK LDWYGTLFPR IPVPIQKEIE LKFRERAKLD
YQREHGDREG DYERHRSRSR SRDRLRERSK DRDRDKDRER SRERDRERDR DRTTGRSRER
RRDSRGRSRE KSSTRPSYAS DKKRKHGGHR YKCKHHLRHH HCRKHKEYCP TKAKKACQEK
LEKNTKS
//
