ID J9BKF3_WUCBA Unreviewed; 531 AA.
AC J9BKF3;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Netrin-1 {ECO:0000256|ARBA:ARBA00015919};
GN ORFNames=WUBG_01144 {ECO:0000313|EMBL:EJW87945.1};
OS Wuchereria bancrofti.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Wuchereria.
OX NCBI_TaxID=6293 {ECO:0000313|EMBL:EJW87945.1, ECO:0000313|Proteomes:UP000004810};
RN [1] {ECO:0000313|Proteomes:UP000004810}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NA {ECO:0000313|Proteomes:UP000004810};
RA Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Hepburn T.,
RA Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M.,
RA Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S.,
RA Walk T., White J., Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT "The Genome Sequence of Wuchereria bancrofti.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJW87945.1}.
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DR EMBL; ADBV01000245; EJW87945.1; -; Genomic_DNA.
DR AlphaFoldDB; J9BKF3; -.
DR Proteomes; UP000004810; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR CDD; cd00055; EGF_Lam; 3.
DR CDD; cd03579; NTR_netrin-1_like; 1.
DR Gene3D; 2.40.50.120; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR008211; Laminin_N.
DR InterPro; IPR002049; LE_dom.
DR InterPro; IPR001134; Netrin_domain.
DR InterPro; IPR018933; Netrin_module_non-TIMP.
DR InterPro; IPR008993; TIMP-like_OB-fold.
DR PANTHER; PTHR10574:SF435; LAMININ SUBUNIT GAMMA-1; 1.
DR PANTHER; PTHR10574; NETRIN/LAMININ-RELATED; 1.
DR Pfam; PF00053; Laminin_EGF; 3.
DR Pfam; PF00055; Laminin_N; 1.
DR Pfam; PF01759; NTR; 1.
DR SMART; SM00643; C345C; 1.
DR SMART; SM00180; EGF_Lam; 3.
DR SMART; SM00136; LamNT; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF50242; TIMP-like; 1.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01248; EGF_LAM_1; 1.
DR PROSITE; PS50027; EGF_LAM_2; 1.
DR PROSITE; PS51117; LAMININ_NTER; 1.
DR PROSITE; PS50189; NTR; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00460};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 1..209
FT /note="Laminin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51117"
FT DOMAIN 329..378
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 397..525
FT /note="NTR"
FT /evidence="ECO:0000259|PROSITE:PS50189"
FT DISULFID 329..341
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 331..348
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 350..359
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 362..376
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
SQ SEQUENCE 531 AA; 60282 MW; E67EB7C3ECB6EE54 CRC64;
MGVMEEVCNI CDASSKTRSH PASHLTDLNN LQNVTCWMSE PSTEYPHNVT LTLSLGKKYE
LTYISIQFCN RLADSMAFYK SMDFGKTWIP FQFYSTECQK IYDRNPSIKI GKHNEQEALC
TNTHALTSMP NRVAFATLEG RPSAFEFEHS PVLQDWVTAT DIRVIFNRLS PDQAELYGLT
NEIGVNITDM DQLKQRYYYS VGELAVGGRC KCNGHASRCI LDKTGNYICD CKHNTAGADC
EHCKTFHLDR PWGRATSENA NHCVACNCNL HAKRCRFNME LYRLSGNKSG GVCINCRHNT
AGRNCHYCKP GYFRDLTKSV THRKVCKACN CHPVGSLSRS CNQSSGQCIC KDGVTGLTCN
QCSKGYQQSR SPLHPCIRKP SHITSYCNSD VALLSKCPKC RAAPKRLTQK KYCKRDYAVE
VQVTRRESVD GWSKYQLIVL AIYKRDTGIR LRRGEQSLWI SGKRTACKCP KIRVGRKYLI
LGRNDTNDIS RPGIVFGART VVLEWNDEDL EKIMRFSKKE KKGQCPARRR F
//
