ID J9DIB4_EDHAE Unreviewed; 271 AA.
AC J9DIB4;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=proline--tRNA ligase {ECO:0000256|ARBA:ARBA00012831};
DE EC=6.1.1.15 {ECO:0000256|ARBA:ARBA00012831};
GN ORFNames=EDEG_03207 {ECO:0000313|EMBL:EJW02365.1};
OS Edhazardia aedis (strain USNM 41457) (Microsporidian parasite).
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Edhazardia.
OX NCBI_TaxID=1003232 {ECO:0000313|EMBL:EJW02365.1, ECO:0000313|Proteomes:UP000003163};
RN [1] {ECO:0000313|EMBL:EJW02365.1, ECO:0000313|Proteomes:UP000003163}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=USNM 41457 {ECO:0000313|EMBL:EJW02365.1,
RC ECO:0000313|Proteomes:UP000003163};
RA Liu Z.J., Shi F.L., Lu J.Q., Li M., Wang Z.L.;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000003163}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=USNM 41457 {ECO:0000313|Proteomes:UP000003163};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Cuomo C.A., Sanscrainte N.D., Goldberg J.M., Heiman D., Young S., Zeng Q.,
RA Becnel J.J., Birren B.W.;
RT "Contrasting host-pathogen interactions and genome evolution in two
RT generalist and specialist microsporidian pathogens of mosquitoes.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJW02365.1}.
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DR EMBL; AFBI03000075; EJW02365.1; -; Genomic_DNA.
DR AlphaFoldDB; J9DIB4; -.
DR STRING; 1003232.J9DIB4; -.
DR VEuPathDB; MicrosporidiaDB:EDEG_03207; -.
DR HOGENOM; CLU_001882_4_3_1; -.
DR InParanoid; J9DIB4; -.
DR OMA; GWKYLNW; -.
DR OrthoDB; 2733051at2759; -.
DR Proteomes; UP000003163; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004827; F:proline-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0006433; P:prolyl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00862; ProRS_anticodon_zinc; 1.
DR Gene3D; 3.40.50.800; Anticodon-binding domain; 1.
DR Gene3D; 3.30.110.30; C-terminal domain of ProRS; 1.
DR InterPro; IPR004154; Anticodon-bd.
DR InterPro; IPR036621; Anticodon-bd_dom_sf.
DR InterPro; IPR004499; Pro-tRNA-ligase_IIa_arc-type.
DR InterPro; IPR016061; Pro-tRNA_ligase_II_C.
DR InterPro; IPR017449; Pro-tRNA_synth_II.
DR PANTHER; PTHR43382:SF2; BIFUNCTIONAL GLUTAMATE_PROLINE--TRNA LIGASE; 1.
DR PANTHER; PTHR43382; PROLYL-TRNA SYNTHETASE; 1.
DR Pfam; PF03129; HGTP_anticodon; 1.
DR Pfam; PF09180; ProRS-C_1; 1.
DR SMART; SM00946; ProRS-C_1; 1.
DR SUPFAM; SSF64586; C-terminal domain of ProRS; 1.
DR SUPFAM; SSF52954; Class II aaRS ABD-related; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000003163}.
FT DOMAIN 193..271
FT /note="Proline-tRNA ligase class II C-terminal"
FT /evidence="ECO:0000259|SMART:SM00946"
SQ SEQUENCE 271 AA; 30798 MW; D620A715B87123DE CRC64;
MTKNNSEVKT ENKNNADNVD VKLSQDLEKI NLNTHKFVYQ SSWGLTTRSI GIALMTHSDS
VGAVIPPRVS QIQVVIIRCG KSSEEVDEYI KKIQSQLIDQ NIRVKLDDRT NVTVGYKFNH
WEIRGVPLRL EIGKKDMAEN KLVAVKRNKL EKIVLENIDI GVKIRIMLDD MHEEMYNAAK
NILDNSIKRV DSWDVFITEI NDKNIALISW CGKISCEENI KEESCIRNDA KEVVTMGAKS
LCIPFEYQEN VKSCIKCGDA GKCIALFGRS Y
//
