ID J9DKS8_EDHAE Unreviewed; 1127 AA.
AC J9DKS8;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Bromo domain-containing protein {ECO:0000259|PROSITE:PS50014};
GN ORFNames=EDEG_03555 {ECO:0000313|EMBL:EJW01992.1};
OS Edhazardia aedis (strain USNM 41457) (Microsporidian parasite).
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Edhazardia.
OX NCBI_TaxID=1003232 {ECO:0000313|EMBL:EJW01992.1, ECO:0000313|Proteomes:UP000003163};
RN [1] {ECO:0000313|EMBL:EJW01992.1, ECO:0000313|Proteomes:UP000003163}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=USNM 41457 {ECO:0000313|EMBL:EJW01992.1,
RC ECO:0000313|Proteomes:UP000003163};
RA Liu Z.J., Shi F.L., Lu J.Q., Li M., Wang Z.L.;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000003163}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=USNM 41457 {ECO:0000313|Proteomes:UP000003163};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Cuomo C.A., Sanscrainte N.D., Goldberg J.M., Heiman D., Young S., Zeng Q.,
RA Becnel J.J., Birren B.W.;
RT "Contrasting host-pathogen interactions and genome evolution in two
RT generalist and specialist microsporidian pathogens of mosquitoes.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJW01992.1}.
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DR EMBL; AFBI03000097; EJW01992.1; -; Genomic_DNA.
DR AlphaFoldDB; J9DKS8; -.
DR STRING; 1003232.J9DKS8; -.
DR VEuPathDB; MicrosporidiaDB:EDEG_03555; -.
DR HOGENOM; CLU_279507_0_0_1; -.
DR InParanoid; J9DKS8; -.
DR OrthoDB; 163389at2759; -.
DR Proteomes; UP000003163; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd04369; Bromodomain; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793:SF132; PHD FINGER PROTEIN RHINOCEROS; 1.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF13831; PHD_2; 1.
DR Pfam; PF13771; zf-HC5HC2H; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00249; PHD; 2.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000003163};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 1040..1109
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 138..173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 928..954
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1127 AA; 131736 MW; 00C262759A091C67 CRC64;
MTDVPREEQS YKKIYPHLVT SKKLKLTIPS SLRKPKQTIE RIKKLRKVTA KEMLVDVQYC
ADINDYEFID SYCLQNPSFR NVFEYDFVVF LYELVMDRIL KEWRLCQLRL IHEYYYEDFT
GESLTIAQRK AIEYKKKNED AENDNGKKGG KKSQTARRKS TRKRASSRLS SCLQENAKKM
SSESFNDSQC ISPSDNCDIL NGDEVSGSIG NYEKNSDVSN CENSVDLNDE GLNNEKSSVK
HVKSCKNKFI SKRNFALQKI KKNISNSREK GDKYCGDADK NKQLSFKKYR ITNPIEDNST
SETHLLCDIC TFPETSQQNI ILTCNGCLIN VHQECYGVPN LEKYSYLEDV KHKFFFLNKL
WFCRKCLFFP EDNPKCKYCP VKGNAFKMIY KTKRWAHILC AKFIENIGFA NTVFLEPIEE
LKEENGEKIE EHSAKNNLNF FGSKNARKCR KKAENEKLEI QVDDTKNLKE GKKSTDFSKT
GKNTNKRHNS INVQNTEKEK EKEICFICTS FAGRTAKCNY DECTVKYHVT CGINFGLYFD
TKNNTTFCQQ HNPEILQDKH EKIQANSFTK LSSYSLLNSK AVNFNMTRLR FYPKIYFRPQ
VRKPLEIRQP EVSFILKVRN MKPQFNEFMA NRILANDLCN FSCKTINCKI ECCFNTKDQQ
NSINEKLEKF GFCKLNSNNL NPDNFVLSDL LQSQKIDESF ESIINAVQYK KCAVKALITQ
FVLDIGAYYN SKCNRYYDTS GFIDMQKREW EKWDASRGIY CCNKMLLNYL NNLQFKSLAD
CVSLKFDPQD LKCLFNVVFV LNKKVLQKRL QDENVDPSDD IKKDENIRND VINQEKILVD
ETLDIVDEDK INDKNRINDV ENKAQNDLQN NGKSISETLK ENISHSTAIL EVQKNNISEQ
NSNTQKTNVD SHVFNSISNK TTSYSETQNI DNTIDNETTD TTKHSVKRKS GVKQNKNHIN
LYHKYHSLLL QKCTNTHIKN FEYHHLEHIL TSLKNLKTVL HKVIQKKNEE TKMIRIQRQH
ILATKDYPTF IKLHLIEKLQ ETESFEVFKY PVTEKIAPRY FSIIKHPMCF ENIEDKLFDK
NYTFDMMLQD LKLISDNCRA YNKSNNFFVN LANLLDKKVD EIVHQYD
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