ID   J9EJI1_WUCBA            Unreviewed;       636 AA.
AC   J9EJI1;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Choline/Carnitine O-acyltransferase {ECO:0000313|EMBL:EJW82581.1};
GN   ORFNames=WUBG_06508 {ECO:0000313|EMBL:EJW82581.1};
OS   Wuchereria bancrofti.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Wuchereria.
OX   NCBI_TaxID=6293 {ECO:0000313|EMBL:EJW82581.1, ECO:0000313|Proteomes:UP000004810};
RN   [1] {ECO:0000313|Proteomes:UP000004810}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NA {ECO:0000313|Proteomes:UP000004810};
RA   Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Koehrsen M.,
RA   Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Hepburn T.,
RA   Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M.,
RA   Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S.,
RA   Walk T., White J., Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Wuchereria bancrofti.";
RL   Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the carnitine/choline acetyltransferase family.
CC       {ECO:0000256|ARBA:ARBA00005232, ECO:0000256|RuleBase:RU003801}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJW82581.1}.
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DR   EMBL; ADBV01002782; EJW82581.1; -; Genomic_DNA.
DR   AlphaFoldDB; J9EJI1; -.
DR   Proteomes; UP000004810; Unassembled WGS sequence.
DR   GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR   Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 1.
DR   InterPro; IPR000542; Carn_acyl_trans.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR039551; Cho/carn_acyl_trans.
DR   InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR   PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR   PANTHER; PTHR22589:SF31; CARNITINE O-PALMITOYLTRANSFERASE; 1.
DR   Pfam; PF00755; Carn_acyltransf; 1.
DR   SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR   PROSITE; PS00440; ACYLTRANSF_C_2; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW   ECO:0000256|RuleBase:RU003801};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003801}.
FT   DOMAIN          41..623
FT                   /note="Choline/carnitine acyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF00755"
FT   ACT_SITE        340
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600542-1"
SQ   SEQUENCE   636 AA;  73286 MW;  C766E528E1C145B2 CRC64;
     MFENPHLRPL SKSSKLWLTL LHLLSKSGLM LHSFQGSLPR LPLPRLNDTL DKHLCTMRPV
     CTDKEYDELV QLTEEFRTGV GRHLQWYLII KSFLSINYVA EWWEDFVYLR QRSPIMINSN
     YYGMDSIVAH PTCNQAARAA TVTWAALLFR RMIERQEIKP FAFLSQFKIP LCTAQYERLF
     NSCRVPYLEK DKFYHWSDAK HVAVYCNGRW FRLAIHNGKR LYEPCELQKG FEAILNEKVN
     SDVEESYIAA LTASDRDVWA QVRRNYFTSG INQLSLHAIE KAAFVVILDE HEVFYDPNDP
     SKLDFWASSL LHGTGCDRWF DKSFNFIIFK NGFFGINAEH SWGDAAVVAH LMEFCAIKTV
     CEYNYDENGN TRGQVESIPK YDRLRWHITS ELNTTIMKCF RTGRALIDDV EMALLVWTKY
     GKGLIKKLHV SPDGFLQLAL QLAFYRNQKK FVLTYEAATA RLFREGRTET VRSCSSYSCD
     FVHAMLDPNQ THQERLKLLN AACNYHQTMY RDAMCGKGVD RHLFALYIVM RYLKLKSPFL
     ERIFPPTFLL STSQTPLNQC GEEVKYANLD PHKFGTAGGG FGPVADNGYG VSYIIVGDDM
     ISFHISSRRS AHNTSSAGLR DDIARSLEDM SLLLQG
//