ID J9EK50_WUCBA Unreviewed; 348 AA.
AC J9EK50;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=PX domain-containing protein {ECO:0000313|EMBL:EJW82846.1};
GN ORFNames=WUBG_06245 {ECO:0000313|EMBL:EJW82846.1};
OS Wuchereria bancrofti.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Wuchereria.
OX NCBI_TaxID=6293 {ECO:0000313|EMBL:EJW82846.1, ECO:0000313|Proteomes:UP000004810};
RN [1] {ECO:0000313|Proteomes:UP000004810}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NA {ECO:0000313|Proteomes:UP000004810};
RA Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Hepburn T.,
RA Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M.,
RA Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S.,
RA Walk T., White J., Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT "The Genome Sequence of Wuchereria bancrofti.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJW82846.1}.
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DR EMBL; ADBV01002598; EJW82846.1; -; Genomic_DNA.
DR AlphaFoldDB; J9EK50; -.
DR Proteomes; UP000004810; Unassembled WGS sequence.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProt.
DR Gene3D; 1.20.80.60; -; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR037831; SNX17/27/31-like.
DR PANTHER; PTHR12431; SORTING NEXIN 17 AND 27; 1.
DR PANTHER; PTHR12431:SF19; SORTING NEXIN-27; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF00788; RA; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS50200; RA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Transport {ECO:0000256|ARBA:ARBA00022927}.
FT DOMAIN 1..83
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT DOMAIN 87..175
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
SQ SEQUENCE 348 AA; 40192 MW; D0BA1D8661E1ED94 CRC64;
MAGRHLGSRR YNEFVQLHNL LKHEFIDFDF PKLPSKWPFS LSEQQLDARR RGLESYLEKI
CAVRVIADSD IMQEFLMEDS LSECAVADVH IRILLPDGNS LLLNIKRHCT AIELYTATQK
RLNMSSEASR CCALFEMAEC GFERKLADDE YPHALYIQNY SSAASSCILL RKWIFDISRE
IELCGRDKLF KELCFWQAVA DVNGGLVSAK EKMFQLKALQ SIERADKYLN MVRTMDGYNR
IVFPHCGCGS RKDGDIILGV EFSQLTIHAC DYEGNLQEEV LVFDWADILG YKVVDNGATF
AFEYARSQKK PKSVKLSTQF AVYMNFCFSR ILEERERRAG LIFFKEEY
//
