ID J9ERF4_WUCBA Unreviewed; 511 AA.
AC J9ERF4;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Histone-lysine N-methyltransferase {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=WUBG_09444 {ECO:0000313|EMBL:EJW79647.1};
OS Wuchereria bancrofti.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Wuchereria.
OX NCBI_TaxID=6293 {ECO:0000313|EMBL:EJW79647.1, ECO:0000313|Proteomes:UP000004810};
RN [1] {ECO:0000313|Proteomes:UP000004810}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NA {ECO:0000313|Proteomes:UP000004810};
RA Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Hepburn T.,
RA Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M.,
RA Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S.,
RA Walk T., White J., Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT "The Genome Sequence of Wuchereria bancrofti.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJW79647.1}.
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DR EMBL; ADBV01005258; EJW79647.1; -; Genomic_DNA.
DR AlphaFoldDB; J9ERF4; -.
DR Proteomes; UP000004810; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0042054; F:histone methyltransferase activity; IEA:InterPro.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR006560; AWS_dom.
DR InterPro; IPR003616; Post-SET_dom.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR PANTHER; PTHR22884:SF474; HISTONE-LYSINE N-METHYLTRANSFERASE LIN-59-RELATED; 1.
DR PANTHER; PTHR22884; SET DOMAIN PROTEINS; 1.
DR Pfam; PF00856; SET; 1.
DR SMART; SM00570; AWS; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS51215; AWS; 1.
DR PROSITE; PS50868; POST_SET; 1.
DR PROSITE; PS50280; SET; 1.
PE 4: Predicted;
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 132..178
FT /note="AWS"
FT /evidence="ECO:0000259|PROSITE:PS51215"
FT DOMAIN 181..298
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 306..322
FT /note="Post-SET"
FT /evidence="ECO:0000259|PROSITE:PS50868"
FT REGION 72..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 357..378
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 471..496
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 72..91
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 511
FT /evidence="ECO:0000313|EMBL:EJW79647.1"
SQ SEQUENCE 511 AA; 59421 MW; 9DE390774D5F08FE CRC64;
MVDQIREFHL DVKRKINEQL KIVIEQISRQ FANLELNLGD RKHWDLPWYR LNWKEVTRRL
IERNRLEKSK REKNSSKAYR IGDRKLPKSR KSDSFVTSAT PSSSKICERN RRSSGDYIKL
KQNVIVDAYP KIEQMQCSCS SGCCGESDEC LNRVVLMECG SSCPRNAICT NKRLFRRECI
ERLRTFQTMN GCGIGVKTDV NIDKGQFICE YIGEVVSMET FNIRSRTDYR YQRNHYALNL
CPGFVVDAYH KGNIARFINH SCAPNCEMQR WSVNGHYRIG LFALRGIHEG EELTYDYNWD
AFEFDDVTIC CCGAPNCRHF LNKNVIMNNR EKELARKARL LLLRNVRKSA AFKLKKFRKE
SQSRSQSRTS KTSLTIPATS NSDEQLEQLC QEVVMKFNDS KLASKKELKK LSNFITELRE
KHASTRTVLE MLESIEMKVN SLLGISGRSL DRRKLDIWRA SFASIKAKHS RQVRKFGKGD
HQQHHQSPKK SKTGPHRTLT AAIDYRYLDS P
//
