ID   J9EVG5_WUCBA            Unreviewed;       283 AA.
AC   J9EVG5;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Pre-mRNA-splicing factor 38 {ECO:0000256|RuleBase:RU367025};
GN   ORFNames=WUBG_07960 {ECO:0000313|EMBL:EJW81132.1};
OS   Wuchereria bancrofti.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Wuchereria.
OX   NCBI_TaxID=6293 {ECO:0000313|EMBL:EJW81132.1, ECO:0000313|Proteomes:UP000004810};
RN   [1] {ECO:0000313|Proteomes:UP000004810}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NA {ECO:0000313|Proteomes:UP000004810};
RA   Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Koehrsen M.,
RA   Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Hepburn T.,
RA   Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M.,
RA   Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S.,
RA   Walk T., White J., Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Wuchereria bancrofti.";
RL   Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for pre-mRNA splicing.
CC       {ECO:0000256|RuleBase:RU367025}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|RuleBase:RU367025}.
CC   -!- SIMILARITY: Belongs to the PRP38 family.
CC       {ECO:0000256|ARBA:ARBA00006164, ECO:0000256|RuleBase:RU367025}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJW81132.1}.
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DR   EMBL; ADBV01003898; EJW81132.1; -; Genomic_DNA.
DR   AlphaFoldDB; J9EVG5; -.
DR   Proteomes; UP000004810; Unassembled WGS sequence.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:UniProtKB-UniRule.
DR   InterPro; IPR005037; PRP38.
DR   InterPro; IPR024767; PRP38_C.
DR   PANTHER; PTHR23142:SF1; PRE-MRNA-SPLICING FACTOR 38A; 1.
DR   PANTHER; PTHR23142; UNCHARACTERIZED; 1.
DR   Pfam; PF03371; PRP38; 1.
DR   Pfam; PF12871; PRP38_assoc; 1.
PE   3: Inferred from homology;
KW   mRNA processing {ECO:0000256|ARBA:ARBA00022664,
KW   ECO:0000256|RuleBase:RU367025};
KW   mRNA splicing {ECO:0000256|ARBA:ARBA00023187,
KW   ECO:0000256|RuleBase:RU367025};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU367025};
KW   Spliceosome {ECO:0000256|ARBA:ARBA00022728, ECO:0000256|RuleBase:RU367025}.
FT   DOMAIN          179..268
FT                   /note="Pre-mRNA-splicing factor 38 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12871"
FT   REGION          226..283
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        226..275
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   283 AA;  34266 MW;  21EA23F3F44ED29F CRC64;
     MANRTVKDAV TVKGTNPQYL VEKIIRTRIY DSKYWKEECF ALTAELLVDK GMELRYIGGI
     YAGNVKPTPF LCLCLKMLQI QPEKDIAVEF IRQEEYKYIR ALGAMYIRLT FTSIEVYKYL
     EPLYNDYRKL RIMNNEGRFE IVHMDEFIDN LLRDERYCDI HLPRIQKRIT LEEVGELQPY
     VSALDEDLDK LSSSDSEDDD DRIRKRKERK LCALFLGVPR RRSYSRERER ERDMDRGRDR
     DRERERERER ERDNDRDKDR NRDRDRRHRT PEYRDRGIIV SAN
//