ID   J9EYR7_WUCBA            Unreviewed;       297 AA.
AC   J9EYR7;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJW87373.1};
GN   ORFNames=WBA_LOCUS528 {ECO:0000313|EMBL:VDM07142.1}, WUBG_01717
GN   {ECO:0000313|EMBL:EJW87373.1};
OS   Wuchereria bancrofti.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Wuchereria.
OX   NCBI_TaxID=6293 {ECO:0000313|EMBL:EJW87373.1};
RN   [1] {ECO:0000313|EMBL:EJW87373.1}
RP   NUCLEOTIDE SEQUENCE.
RG   The Broad Institute Genome Sequencing Platform;
RG   Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Koehrsen M.,
RA   Alvarado L., Berlin A., Borenstein D., Chapman S.B., Chen Z., Engels R.,
RA   Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.R.,
RA   Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B., Mehta T.,
RA   Park D., Pearson M., Richards J., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Haas B.,
RA   Henn M.R., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Wuchereria bancrofti.";
RL   Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:VDM07142.1, ECO:0000313|Proteomes:UP000270924}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the MAPRE family.
CC       {ECO:0000256|ARBA:ARBA00010729}.
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DR   EMBL; ADBV01000410; EJW87373.1; -; Genomic_DNA.
DR   EMBL; UYWW01000073; VDM07142.1; -; Genomic_DNA.
DR   AlphaFoldDB; J9EYR7; -.
DR   InParanoid; J9EYR7; -.
DR   OMA; NNHPPPN; -.
DR   Proteomes; UP000004810; Unassembled WGS sequence.
DR   Proteomes; UP000270924; Unassembled WGS sequence.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.5.1430; -; 1.
DR   Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR   InterPro; IPR001715; CH_dom.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR004953; EB1_C.
DR   InterPro; IPR036133; EB1_C_sf.
DR   InterPro; IPR027328; MAPRE.
DR   PANTHER; PTHR10623:SF6; EB1, ISOFORM F-RELATED; 1.
DR   PANTHER; PTHR10623; MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER; 1.
DR   Pfam; PF00307; CH; 1.
DR   Pfam; PF03271; EB1; 1.
DR   SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR   SUPFAM; SSF140612; EB1 dimerisation domain-like; 1.
DR   PROSITE; PS50021; CH; 1.
DR   PROSITE; PS51230; EB1_C; 1.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW   Cell division {ECO:0000256|ARBA:ARBA00022618};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Microtubule {ECO:0000256|PROSITE-ProRule:PRU00576};
KW   Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW   Reference proteome {ECO:0000313|Proteomes:UP000270924}.
FT   DOMAIN          15..117
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
FT   DOMAIN          214..284
FT                   /note="EB1 C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51230"
FT   REGION          129..171
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          215..242
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        156..171
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   297 AA;  33422 MW;  0680BAF93035E3F3 CRC64;
     MSVVNVYATS ATTENLSRHE MLMWVNDCLQ SNFAKIEEMH TGAAYCQFTD FLFPGSIQLR
     RVKWNSRLEL DWLSNWKLLQ TSWKTLGVDK IVPVEKLIKG KFQDNFEFLQ WFKKFFDANF
     DGHEYDPLEA RSGEPLPSDV KANAPSRMPA RSSAPPVKKS TLSTSNASMN KGEVRKAPVL
     GGKHNPTRTA APLTTTTAAR AAAHPIQPVV DPQVVANLKR ELEEAKGQIA EGDNVIVSLE
     KERDFYFSKL RQIEVICQDN EQIGTIDVAR VIAILYETEE GFAPPDENEV ENGDEIY
//