ID J9ICU0_9SPIT Unreviewed; 925 AA.
AC J9ICU0;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=PWWP domain containing protein {ECO:0000313|EMBL:EJY76249.1};
GN ORFNames=OXYTRI_02244 {ECO:0000313|EMBL:EJY76249.1};
OS Oxytricha trifallax.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC Stichotrichia; Sporadotrichida; Oxytrichidae; Oxytrichinae; Oxytricha.
OX NCBI_TaxID=1172189 {ECO:0000313|EMBL:EJY76249.1};
RN [1] {ECO:0000313|EMBL:EJY76249.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JRB310 {ECO:0000313|EMBL:EJY76249.1};
RX PubMed=23382650; DOI=10.1371/journal.pbio.1001473;
RA Swart E.C., Bracht J.R., Magrini V., Minx P., Chen X., Zhou Y.,
RA Khurana J.S., Goldman A.D., Nowacki M., Schotanus K., Jung S., Fulton R.S.,
RA Ly A., McGrath S., Haub K., Wiggins J.L., Storton D., Matese J.C.,
RA Parsons L., Chang W.J., Bowen M.S., Stover N.A., Jones T.A., Eddy S.R.,
RA Herrick G.A., Doak T.G., Wilson R.K., Mardis E.R., Landweber L.F.;
RT "The Oxytricha trifallax Macronuclear Genome: A Complex Eukaryotic Genome
RT with 16,000 Tiny Chromosomes.";
RL PLoS Biol. 11:E1001473-E1001473(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJY76249.1}.
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DR EMBL; AMCR01011610; EJY76249.1; -; Genomic_DNA.
DR AlphaFoldDB; J9ICU0; -.
DR EnsemblProtists; EJY76249; EJY76249; OXYTRI_02244.
DR OrthoDB; 181099at2759; -.
DR CDD; cd05162; PWWP; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 1.20.930.10; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR InterPro; IPR000313; PWWP_dom.
DR InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR PANTHER; PTHR10688; PWWP DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10688:SF5; PWWP DOMAIN-CONTAINING PROTEIN 1-RELATED; 1.
DR Pfam; PF00855; PWWP; 1.
DR SMART; SM00293; PWWP; 1.
DR SUPFAM; SSF47676; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50812; PWWP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 23..78
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 114..140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 164..268
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 301..322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 363..474
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 781..809
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 903..925
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 80..107
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 164..216
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..258
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 363..383
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 390..407
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 408..422
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 423..474
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 925 AA; 105630 MW; D96292A48F72E7BE CRC64;
MSTQVGGQNG KTRASKESQK FRDGEIVWAK VRGYSWWPAK IGKKENNGDK EGKYRVNFIG
DKTYQDLPED KLADFISNYI DYAKIKKRDL QDAIEQAKKL LSQDEQSAIE RLLRNEDTNA
KQSEKGGNNE KVDVEKEEKI NVKQMRGSQI LTSAKGLQPD MIKQSVGKST AISHSSCDHS
TTPTKASAKD LQISSSKGSS SAKKQDQSSI TNIRDQARTL VKEKTPVMNR RNLKTLQKQS
ARDRKYTKDS RSEGDASRDL IDEMEDEESQ IICTKSKTLS INHRNKRLKK TAKLESDAQS
EVQEVQNNDI MQVDLPHDEG EQEDKKVLNS TTQIDEDTHN NQIIGGDQEV MKVDSSEIEE
CKSEQSIFEE PSCHKDVQEP LPKERRQSAQ QAIKVIQSVT TKQPKSLSKS KIIEKRQTID
KPRTPQTKTG ESQKQNSQLV KMSSQKNLCQ TKPQTSSGSD STRHSPYTNI HQGNKSLKGV
SQSISNITVQ NQPSHIQSAT QCQVTKECTQ ISKTIRNIIK FQQQEEEQFR KKNQLDKSQI
DLLAENKECL LMMQQQVPTL YKHLMQLQKT EITLNILEDT GIAKTLKYLS DYCELYKREI
PPLQSIFQNI QALLLKWKNY VTKQLFEEKS SHIEDFQKEK YRLKLEKLEK KSGAKIKSSN
IVQQDLSYED KKVPQTTKAN ASLSKITEQQ QNQQLIQNFQ QHQILHQLSQ AQIISDDEFK
NNTLLQQKLD LLKRQNSQNA QTSNNGIRSI LLQAALNSSN NRQQQEGLAR KFSTDSQYTR
TIQNQQSEEK LQQTQQQYQH SNSGTYESGK DLQQNLTQIP QLQQPQTIQP QQQQPLAQQQ
ALALGLGNLQ LDSISSIAQM LLQNIYNNNP INKTGSPSRQ QILTGFQRPT HSNFLLRDIN
PHHQQQQQNQ NENDQLKDNI AAQFT
//
