ID   J9ICY6_9SPIT            Unreviewed;       626 AA.
AC   J9ICY6;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=ADP-ribosylation factor GTPase-activating protein, putative {ECO:0000313|EMBL:EJY72018.1};
GN   ORFNames=OXYTRI_06985 {ECO:0000313|EMBL:EJY72018.1};
OS   Oxytricha trifallax.
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC   Stichotrichia; Sporadotrichida; Oxytrichidae; Oxytrichinae; Oxytricha.
OX   NCBI_TaxID=1172189 {ECO:0000313|EMBL:EJY72018.1};
RN   [1] {ECO:0000313|EMBL:EJY72018.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JRB310 {ECO:0000313|EMBL:EJY72018.1};
RX   PubMed=23382650; DOI=10.1371/journal.pbio.1001473;
RA   Swart E.C., Bracht J.R., Magrini V., Minx P., Chen X., Zhou Y.,
RA   Khurana J.S., Goldman A.D., Nowacki M., Schotanus K., Jung S., Fulton R.S.,
RA   Ly A., McGrath S., Haub K., Wiggins J.L., Storton D., Matese J.C.,
RA   Parsons L., Chang W.J., Bowen M.S., Stover N.A., Jones T.A., Eddy S.R.,
RA   Herrick G.A., Doak T.G., Wilson R.K., Mardis E.R., Landweber L.F.;
RT   "The Oxytricha trifallax Macronuclear Genome: A Complex Eukaryotic Genome
RT   with 16,000 Tiny Chromosomes.";
RL   PLoS Biol. 11:E1001473-E1001473(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJY72018.1}.
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DR   EMBL; AMCR01015493; EJY72018.1; -; Genomic_DNA.
DR   AlphaFoldDB; J9ICY6; -.
DR   EnsemblProtists; EJY72018; EJY72018; OXYTRI_06985.
DR   OrthoDB; 1022106at2759; -.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR   InterPro; IPR037278; ARFGAP/RecO.
DR   InterPro; IPR001164; ArfGAP_dom.
DR   InterPro; IPR038508; ArfGAP_dom_sf.
DR   PANTHER; PTHR45686; ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED; 1.
DR   PANTHER; PTHR45686:SF18; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN GCS1; 1.
DR   Pfam; PF01412; ArfGap; 1.
DR   PRINTS; PR00405; REVINTRACTNG.
DR   SMART; SM00105; ArfGap; 1.
DR   SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR   PROSITE; PS50115; ARFGAP; 1.
PE   4: Predicted;
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00288};
KW   Zinc {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-ProRule:PRU00288};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00288}.
FT   DOMAIN          79..162
FT                   /note="Arf-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50115"
FT   REGION          1..50
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          424..443
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          601..626
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        424..441
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        601..618
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   626 AA;  72335 MW;  B290C7BCDCF93821 CRC64;
     MSEYNSQQSL SAQKKKLQNY SSNQYHSENQ NSNHNSSNNN QLNQSPYQST TNTNTNVTVS
     VYEQDANEQR RTNQLSLTQR IFSKLLSDQC NKFCFDCGTE NPHYVSINQG IFLCFNCAMS
     IHRLHYGVEI SYIKSVFNDP WNHQQLRVLI KSGNKELKEF LEFYDLLYEP IQKRYNTQAM
     QFYRDRLRAT VDGQTYSKEK PSYEQGRKQV QMSTTQQPIL YHYLNYRDIM QELFEWETLS
     LIEQSSPLMQ RFDMYIADLE KNNEQIFLQN GQLPPKDQIP LNPNLPPKPH VINEPYCDNN
     NAISNEDYIL LINKLNEFAD NTYTFGESIF RKIEEVGNIN EKLKVTADKL VNRGSEVGAS
     IFKRTRDSIT QINQSSRMSQ LKEKASDKLT TLGGKIWGFF GSAAASNEAK LQISNQEQQK
     AQLTQNSQIK SQSNQSQKRN NDTLQEETKM HNEFEIKKET TPDHYQIQQL DSNILANSSV
     QKDHQLIKSN TLPNKNHRSA NNESMQHSKT MINNGLNDLN YLDSLQKQQH NNDITPNQIQ
     SQQSKFTFIN TTASTGDANI NQNGNINNNT LDSANSSISR EDMGIGITKD MKRLSFRDSM
     FHSSSRTEEQ KQQKKIDDYS IESNIL
//