ID J9IFR1_9SPIT Unreviewed; 585 AA.
AC J9IFR1;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Ion transport domain-containing protein {ECO:0000259|Pfam:PF00520};
GN ORFNames=OXYTRI_05592 {ECO:0000313|EMBL:EJY73278.1};
OS Oxytricha trifallax.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC Stichotrichia; Sporadotrichida; Oxytrichidae; Oxytrichinae; Oxytricha.
OX NCBI_TaxID=1172189 {ECO:0000313|EMBL:EJY73278.1};
RN [1] {ECO:0000313|EMBL:EJY73278.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JRB310 {ECO:0000313|EMBL:EJY73278.1};
RX PubMed=23382650; DOI=10.1371/journal.pbio.1001473;
RA Swart E.C., Bracht J.R., Magrini V., Minx P., Chen X., Zhou Y.,
RA Khurana J.S., Goldman A.D., Nowacki M., Schotanus K., Jung S., Fulton R.S.,
RA Ly A., McGrath S., Haub K., Wiggins J.L., Storton D., Matese J.C.,
RA Parsons L., Chang W.J., Bowen M.S., Stover N.A., Jones T.A., Eddy S.R.,
RA Herrick G.A., Doak T.G., Wilson R.K., Mardis E.R., Landweber L.F.;
RT "The Oxytricha trifallax Macronuclear Genome: A Complex Eukaryotic Genome
RT with 16,000 Tiny Chromosomes.";
RL PLoS Biol. 11:E1001473-E1001473(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJY73278.1}.
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DR EMBL; AMCR01014372; EJY73278.1; -; Genomic_DNA.
DR AlphaFoldDB; J9IFR1; -.
DR EnsemblProtists; EJY73278; EJY73278; OXYTRI_05592.
DR OrthoDB; 188670at2759; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR024862; TRPV.
DR PANTHER; PTHR10582:SF2; INACTIVE; 1.
DR PANTHER; PTHR10582; TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN; 1.
DR Pfam; PF00520; Ion_trans; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 101..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 65..195
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
SQ SEQUENCE 585 AA; 67761 MW; 9EDD134B851036B3 CRC64;
MQGMISPQQQ LGLTICVIVW MWYYNANLDI VQLEGSYGGS LTRNQVFVLS VIEDISDGVF
RFDMLLAVHC GFLWLKVTML LKLTRSFGPL IKIVINMMQD ILEFFVIWSI NLVFFSCVGM
LLFGELDQYN SIYDTLVMFI QSALGAWDLT IYDNILIGKE FGQVYHLIFI IFNTVLLINL
IIAILATTFS ILNDKKLALY YDGIIEAIPT YKYDKLYGSI ICAFPPFNMI TLPFSFAFLQ
LKNIKIIKSL NLLLLHFAYS PVYLLTLLSF AIGNIILMPI CYIYTVSMKV QILFTDREHI
LRSLLSATSC VLLGIPMILV TQFTDLYYFT VHSYSSNCDK LMTSVKPKIS QRSILILYKI
AKSCYKQDIK SIENKQIIKK VREDLQIHED LHCLIYGVNS NNSTQYNIAK EQEPLDTKSH
SRERYLKNIQ VFNCIKRVIK NCSNNSNQLV DIQLLYYLTK EVKISLNITL QNLNKDLAKS
IPSPHQINQK PLKIMAKNSH NIENQGFILK YQKERKNIKL EFAFSNPRRV LQSLEDKPLK
LLQENNVRRI KLILKLHILV FTERSIDRDQ GYETIAKLNK WIIVQ
//
