ID J9IUQ6_9SPIT Unreviewed; 1467 AA.
AC J9IUQ6;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=WD-40 repeat protein {ECO:0000313|EMBL:EJY76215.1};
GN ORFNames=OXYTRI_02278 {ECO:0000313|EMBL:EJY76215.1};
OS Oxytricha trifallax.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC Stichotrichia; Sporadotrichida; Oxytrichidae; Oxytrichinae; Oxytricha.
OX NCBI_TaxID=1172189 {ECO:0000313|EMBL:EJY76215.1};
RN [1] {ECO:0000313|EMBL:EJY76215.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JRB310 {ECO:0000313|EMBL:EJY76215.1};
RX PubMed=23382650; DOI=10.1371/journal.pbio.1001473;
RA Swart E.C., Bracht J.R., Magrini V., Minx P., Chen X., Zhou Y.,
RA Khurana J.S., Goldman A.D., Nowacki M., Schotanus K., Jung S., Fulton R.S.,
RA Ly A., McGrath S., Haub K., Wiggins J.L., Storton D., Matese J.C.,
RA Parsons L., Chang W.J., Bowen M.S., Stover N.A., Jones T.A., Eddy S.R.,
RA Herrick G.A., Doak T.G., Wilson R.K., Mardis E.R., Landweber L.F.;
RT "The Oxytricha trifallax Macronuclear Genome: A Complex Eukaryotic Genome
RT with 16,000 Tiny Chromosomes.";
RL PLoS Biol. 11:E1001473-E1001473(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJY76215.1}.
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DR EMBL; AMCR01011643; EJY76215.1; -; Genomic_DNA.
DR EnsemblProtists; EJY76215; EJY76215; OXYTRI_02278.
DR OrthoDB; 188816at2759; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR024862; TRPV.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR10582:SF2; INACTIVE; 1.
DR PANTHER; PTHR10582; TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1041..1062
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1074..1094
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1114..1132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1139..1159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1179..1199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1244..1266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1045..1275
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT COILED 1406..1440
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1467 AA; 173004 MW; A1C747057C429AFC CRC64;
MNSQSQIEQQ HKEWRYKFDV NSEVTDVFGA KLLHSNDDLK NMERPTIIQD CSKIVSLNYK
SQKIELRDLD TLEIIKEIDT HGYFIQFFND GEYFQNQIDD SQYQRCSGYL YELETLTTEI
YNLNEYLEDV DKNRENNFFQ YLKVEKVNVG DTMLQFFKFS ETSILIINEK DKGNGNNFII
YNFPECQKAQ ENKLKYTLSI PIGDANSKLD NDIKNGKVDS TKQNKFLYKY ECFDSQEIRG
FYSVHKIAQF SLFENLLIFT TVENTLCAIN MSYEKFKTNF IETAQFFKGD FKLDITSNVC
VQIEESDSKL SFFQIINREY KQDKKEMIEL NLIGIIDSNL KIIKYIQLVN DQMIFVFGVQ
NEKDEFLEIL MIDAYTGRLI NSYKIENLTT LQGFQYSKIT QQFYLYNIYH NEQQYDDVQE
LFNLDFLYSS FNTVDKISLP REYKIQTFMS SKNSILLYKY DKKAKCYVIR TEGFTIGTIN
FEKGTVEDTK FIKEDTIKIR KVFEFQENDN LGIIIEIQVY VKLFVYNCGN LEKIKEIKVN
NYSEISLIYK QENGSKWYAC AFKDSVHFYN LEQQQFEKGL DVFKKPTFQI QTPLQESIKT
IFLNTNNQLL YISTNNSLYH YDMTNNVFLL DLTINTQLKT QFSFINAENQ LVLLNQGYQT
DIYNLSYKQN KWFYSQKVSI DNSRGLKIDF DKADENITFI KDYNNSTAFI LENSFEFEEK
IFKHYSVFRV STLVGSQTNG SPYKFDFFHY QDLKRQTIPW QTLEIEQLNQ KFTLYDDMEN
QIIGFIQQSY NTQDIQKFLN YRNSSLTDVD IMNNIKKEGN LKKLLMYYPQ IGNILNLVIS
RPRVIEYLIK QFQLLNSSEL PILIFLNDQQ SPLDVAIKAN QIKSVSLYLD LIVKFQNNHS
FNYLIDKNLI SLIQKSISLS EYFESNLPII KVNNKNYPDL HFDDQEIIVG IDCIDQPRDL
LDKYNEILGQ ELQQNQDGDQ QQFPIEYHLI NFPETLTKEP TKLMKVLSET DNMELFDALA
IQTIINFKWK QYTKSFFQTQ FNIFLIFCFT FLFEIMYSFT NVDRKSDPPV DQRNIYVFCL
LKSLATIVLT YFLIYETKQA LKQENYFKEI WNFFDYMLIL TYIGYIILEI FTPFNDSVII
IKLIIVFLSF LKVNFFLRIY DGFSFLVSMM AAVFVDLKYF IGFFLIFILE FGIVFAILFD
ATAIEEYQGI GISAYMMMAF RTSSGDFNVD SYKDQSSTLV VISWLAWIVA VMLLNVMFMN
FIIAVISESY EKVMQKLVAE SYRVKVQMIV ERELQFSDEE LKSTKLFPKY MLLRRPVSSD
SNEQGEWQGF VKDIKQSIRT VAAKQKTEII ANLKSQNNNT KSFDLGIKSL EKRFGQIDSN
LKSNDENIKV QDQSIKQLVT SQKELVTSQN EKFNELEKSI TNLNNKISSQ DNEIQSSQKM
IIQFIEEYRL ENQKTQALLQ SLQKPQQ
//
