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Database: UniProt
Entry: J9J7N3_9SPIT
LinkDB: J9J7N3_9SPIT
Original site: J9J7N3_9SPIT 
ID   J9J7N3_9SPIT            Unreviewed;      3344 AA.
AC   J9J7N3;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   30-AUG-2017, entry version 31.
DE   SubName: Full=Cation channel family protein {ECO:0000313|EMBL:EJY82860.1};
GN   ORFNames=OXYTRI_19523 {ECO:0000313|EMBL:EJY82860.1};
OS   Oxytricha trifallax.
OC   Eukaryota; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC   Stichotrichia; Sporadotrichida; Oxytrichidae; Oxytrichinae; Oxytricha.
OX   NCBI_TaxID=1172189 {ECO:0000313|EMBL:EJY82860.1, ECO:0000313|Proteomes:UP000006077};
RN   [1] {ECO:0000313|EMBL:EJY82860.1, ECO:0000313|Proteomes:UP000006077}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SB310 {ECO:0000313|Proteomes:UP000006077};
RX   PubMed=23382650; DOI=10.1371/journal.pbio.1001473;
RA   Swart E.C., Bracht J.R., Magrini V., Minx P., Chen X., Zhou Y.,
RA   Khurana J.S., Goldman A.D., Nowacki M., Schotanus K., Jung S.,
RA   Fulton R.S., Ly A., McGrath S., Haub K., Wiggins J.L., Storton D.,
RA   Matese J.C., Parsons L., Chang W.J., Bowen M.S., Stover N.A.,
RA   Jones T.A., Eddy S.R., Herrick G.A., Doak T.G., Wilson R.K.,
RA   Mardis E.R., Landweber L.F.;
RT   "The Oxytricha trifallax Macronuclear Genome: A Complex Eukaryotic
RT   Genome with 16,000 Tiny Chromosomes.";
RL   PLoS Biol. 11:E1001473-E1001473(2013).
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EJY82860.1}.
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DR   EMBL; AMCR01005510; EJY82860.1; -; Genomic_DNA.
DR   EnsemblProtists; EJY82860; EJY82860; OXYTRI_19523.
DR   Proteomes; UP000006077; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005216; F:ion channel activity; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   Pfam; PF00520; Ion_trans; 4.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006077};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006077};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    636    661       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    681    701       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    713    733       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    773    792       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    844    867       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    873    898       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2105   2128       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2140   2161       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2173   2193       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2238   2261       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2314   2335       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2509   2532       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2548   2570       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2591   2619       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2703   2727       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2784   2807       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2883   2902       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2964   2986       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      643    908       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     2109   2344       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     2471   2736       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     2763   2990       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   COILED     1625   1652       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   3344 AA;  384450 MW;  04A56BAFA793CD38 CRC64;
     MTKANKVQSL QQNRNSLPNN NQFQQNQSNF KNNLDINHAN YINAGIQSQN MQDPLQHQWG
     QNPKKESDSL NQRQSASNNQ SQQQLSQNKL SRYDEVDLDK EDEMMKSSSS FGLPSDSYND
     NISDKEIMSD RGAAASGAYN SNKKKQYSPV RQQNQNVTNF ESNHQQNKQS KGFNSTQKPY
     ENGNINLNGT QEPNLDVSFE FLDETKKNAN QIKQQQLNIY NEQKRKLDQI EDLSDMIDSP
     GLNKNGLNLG GANKMNSLTE NNNTAKFRLP LYHNQHQQSL DQTTKRNDEK EITRSTEYPT
     FLNNRKEPVN NVNDDSYISA NSGVNLITGN FDNSFIISDS KNMSQTLNQT QLTGQRIINN
     NYQNIVNMRQ QTTNEIKTQP SLQIPVNQTQ SLSLTNPNQN NVLGKKNPAF GTQKSQRLTK
     PKINLESIAE MQSINQKHGS VGGNGNKVQP MQSIEDSYLN GGQSPLDSSQ LNLNGHHRNF
     SADQDNIRNV PSRKNIYEQT ISEDIFQNEG PVTLRESNDY FEFREDSEYQ QHRHRFQKRL
     QIPDDESERS KFIKMPDVTA SKTQLQEEIG YVLSKNTDEN FKDEVRNKKD VEANSLAFYR
     IVDKDPIDVV NDYHDRCPCL SLRKLFMKAR IIINRLALVI ITNKYFETIS IMVIIANSLF
     LALDDPLTQQ QPAYQDVSES VFQYLYTAEM ALKIIGYGFL FNKGAYLRDT WNILDFIIVI
     SGYLSLILSG GGVNLSVLRS FRVIRPLRTI SSIEGLRVIV QALVSSLPLL RDTILVLLFF
     FLIFAIAGVQ LFSGALMNRC FDVETGVRDV KNVLCGGGSD CLPGQACGKT MENPNFGATN
     FDNIFYAFLQ IFQTVTLEGW TTIMIAVEQT VGQWTIIFFI PIVFIGAFFL LNLTLAVIKS
     KFTEEHHKNK EKKNENQSKK KKPKIYGDES EEDDVDILNQ GKDEAAQTPK MTKIQKRIKD
     IEENQEISPR SKRILKDKAK LEELLKRIDF AIKQRDVKDK ITPRGSSVFS FSQGSLEHIT
     SAKNNKMSKF NKKLGQSKLN YADIFNSRFF MNQLNEKYTY NSFFRVEDQD NQFNNSLVEF
     NTSLMQNNIS KLNSSGLNLL AGNSKTRRRE NEDAIKEDDQ EHSYGISGLI DDEDKLDDKK
     YARSDEKVKI IEGAPQPLIE GGFNRTQTLT KNKVSTWLGQ VFEIQKQPQQ EDQPNSARLL
     MGGFAGIKTK QFSEKPNSEE IKRLKKEIYE KITKNFDVFD FFEDNNGDDE FSEDQFQDDL
     DLDNLNSYSS SRGINRQINE EELVQILDSN SQNLSPQNEV KYQRKSTMAT VETKSVIKNR
     RFQFRDIQQQ PQNVSESGIQ PQNEQNLTSY VTGGLNGPLN DNTTFTTTHN NLRTSNGVNT
     LGKKKQIQRL ATQSPQKNMF RNLKPIDDLL EEEDILKGGV KTIKPKRENS ESFKQKAVKF
     MQGCTSKKKR RIEIIDTEVE ELLKRSRSQQ PSSKTEINRI KPLNLMQNVN RTQVYGSTSM
     RNNTVTVRAL SENKKQLKLQ EKHIRFKQKE EKMRQRRSKF FSQALKDIGK TPEQITKDLK
     LRAEQRRFIE LKGGFTTTKK AKKNFLMRSG TQDFEKDSQK KESFRKNELS VDDYDEERSP
     SQNGVKGYEK ELKQIQKEIN KKKGEQDEVQ DMDKILTQQK KKLIIRMKNY QFSSVNDIFE
     QRDIKLKESI HQNINSSQKQ AFFLKDGPQT KTKKPKEYNP YQKKVLQTQK KYFEDLLVNE
     VLDSDDNQET ILKRLEDEYN VDHRSNIHVT GTLSIVINKP HSENKILNKN YYDQINPQRK
     IDTILEEPLA QSMFVLSKEA LSDNDSIIFQ DQKSSRSHYI NGNQSQELMP VQYLGGNTQR
     IPLKRTNTKL SGGSKGSNVK SALQKKNTVR PSSLHNDKRG QSSRIQGLNQ NYMKNSNQSQ
     KVKQGTQQSV QAPKEINYYL PRPEAFTDKQ ILKRLNDEAK KSRVFSSIHH SKLPKKIGHL
     GEEVIPLPEK KKKKKRKVGI DGVHLDTHRE EDGDDEFSET SIDEPIVNND YFIDRNLDYY
     KQILAAKHAA ISRPIDLIEW SGQDIMQRFD PYKARIALDS LNKIRVWPKG FYGKMKRARV
     GLKKIIKSSF VDNLMTACVF ANTVVLAIDS YGIDPATTEA LTTCNTLFTI MFAVEMFLKI
     LAVGITKYLR DKLNYMDGTI VILSMVELVF LSGKGALKAL RSIRIIRAFR VLRVARLLRG
     LKSMMNIIAV IQRSISSFIY LALLLFLFIF IYALLGMQIF GGSFQQEGAP NRYNFDTFNQ
     AFVTSFILLS TENWNTVMFF AFGSNVNKFI SSIYFISCIF IGNFMLLNLF LAILLDSFTA
     VEEEDHDTTE KRIAREKQRI IDLESKEGEE FIQGLEGIDL DMANKIGNNN KSKKKKKKKK
     NPSSGVNDGP LNNILDESVE IDIETLNSKK QEMKEQKKVL FKGIECQKAL YLFSQENKLR
     IKLYEVVTNS KFETLILCVI ILSSFKLIFD TYTSTLTEDD PVVVISSQLD YVFTSIFTLE
     LVMKCIAFGF IMDRNSYLRE SWSQLDCFIV ATSLIDATFS GVNLPIIKIL RLLRILRPLR
     FISHNSSMKT VVVALLSSMG AILNVGIVVI VVFLMFAILG VNLFAGKLQY CSVNPYVVKN
     KLDCFQVRGQ WKTFNQNFDN VPRAMITLFV VATQEGWPDV MYAYTDITGI ETGPRYGESA
     INAYFFIAFV FIGSFFFMNL FVGVLFMNFE AAQRDEKEAL LLDGDEMKWV DMMKMIVQTK
     PEIMAMSFEG QTVSYKKSLE VANYIFTGIF ALEAILKFIA NGTAYFLPGW HKFDIFVVFA
     SFLDIVLNQL STSALKPLRV APQILRILRV LRVSRLFKLL NKAKGLQALI QTITFSLPSL
     FNVFALLLLV YFIFAVLGVF MYQDISQGTI IDPIYMNFVN FSQALIILLR ISTGEDWPTI
     MYDTMNTDAD CISGKNCGIS YSPVFFIAFV MICSYVMLNL FVLIILQQFE LYYLPQENIL
     QQFREDLYKF KVAWNKFSKE FEGIKIRSLD LLSYFKDLDG NLGMKEDSEK SVMRNIVKMN
     LQCDEEGFIF FNELLFKAMK RIYGKERTKK RMLLEFELRT LDKLQQLTNK QQMKSRKNDR
     IKAVTVNPFL SVMYKNMSFK AWLKIFKTNI PKRNDEVEYN LDRESSEEEE NQVEVEEYYY
     VTEVDESCHS DVIDEESSQN QSGEENNTRK KRPIPIQAAR SLKKSPINSP YPRSKRGSSH
     QKHRFHKNSD NEQGHSPKKY NKQESSRQYN KQLSSRQHHM ESQDLQILQE DQILQETQQR
     GKQDRKINIP TLGVSALSNQ KIISGSNVIA ELKTINDYPT SKRL
//
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