ID   J9JA03_9SPIT            Unreviewed;       462 AA.
AC   J9JA03;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   24-JAN-2024, entry version 38.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJY88358.1};
GN   ORFNames=OXYTRI_16579 {ECO:0000313|EMBL:EJY88358.1};
OS   Oxytricha trifallax.
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC   Stichotrichia; Sporadotrichida; Oxytrichidae; Oxytrichinae; Oxytricha.
OX   NCBI_TaxID=1172189 {ECO:0000313|EMBL:EJY88358.1};
RN   [1] {ECO:0000313|EMBL:EJY88358.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JRB310 {ECO:0000313|EMBL:EJY88358.1};
RX   PubMed=23382650; DOI=10.1371/journal.pbio.1001473;
RA   Swart E.C., Bracht J.R., Magrini V., Minx P., Chen X., Zhou Y.,
RA   Khurana J.S., Goldman A.D., Nowacki M., Schotanus K., Jung S., Fulton R.S.,
RA   Ly A., McGrath S., Haub K., Wiggins J.L., Storton D., Matese J.C.,
RA   Parsons L., Chang W.J., Bowen M.S., Stover N.A., Jones T.A., Eddy S.R.,
RA   Herrick G.A., Doak T.G., Wilson R.K., Mardis E.R., Landweber L.F.;
RT   "The Oxytricha trifallax Macronuclear Genome: A Complex Eukaryotic Genome
RT   with 16,000 Tiny Chromosomes.";
RL   PLoS Biol. 11:E1001473-E1001473(2013).
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000256|ARBA:ARBA00004604}.
CC   -!- SIMILARITY: Belongs to the WD repeat DCAF13/WDSOF1 family.
CC       {ECO:0000256|ARBA:ARBA00005649}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJY88358.1}.
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DR   EMBL; AMCR01000390; EJY88358.1; -; Genomic_DNA.
DR   AlphaFoldDB; J9JA03; -.
DR   EnsemblProtists; EJY88358; EJY88358; OXYTRI_16579.
DR   OrthoDB; 5472351at2759; -.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR007287; Sof1.
DR   InterPro; IPR013979; TIF_beta_prop-like.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR22851:SF0; DDB1- AND CUL4-ASSOCIATED FACTOR 13; 1.
DR   PANTHER; PTHR22851; U3 SMALL NUCLEOLAR RNA U3 SNORNA ASSOCIATED PROTEIN; 1.
DR   Pfam; PF08662; eIF2A; 1.
DR   Pfam; PF04158; Sof1; 1.
DR   Pfam; PF00400; WD40; 3.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 3.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW   ProRule:PRU00221}.
FT   REPEAT          107..146
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   DOMAIN          216..324
FT                   /note="Translation initiation factor beta propellor-like"
FT                   /evidence="ECO:0000259|Pfam:PF08662"
FT   REPEAT          295..336
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          338..379
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   DOMAIN          371..456
FT                   /note="Sof1-like protein"
FT                   /evidence="ECO:0000259|Pfam:PF04158"
FT   REGION          428..462
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        448..462
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   462 AA;  53620 MW;  B8B7FDD09249E1BD CRC64;
     MVKVKTICRN EKEYQKQTNN ELLKVYRNPS KSVLHPFQKA REYQRALNAA KLEKIFAKPF
     IEALDDHSDG VTCLAKNRYN LVDMLSGSAD GEIIYWSMSE RKSKFIINAH ANFVRGVSFA
     NNKTLSADTI FVSSGDDKKV QIWSLQGIKQ QYEKNEGLKG FKNYTPKASF LSKCQLHNID
     HSYDQNLFAT AGSVVQIWSY ERSTPIQSFE WGVDTVTKVK FNPSETNIIA SISLDRSIVL
     YDIRGNTALQ KINMKNKCSA ICWNPYEPMN FVVGNENSNV YTFDMRKLDA AKMIHKDHIQ
     AVLDIDFAPT GREFVTASFD KTIRIFPYND GRSREVYHTK RMQQVNSILY SMDNNFIFSG
     SEDTNIRVWK AHAGDPMKPL LPREKEKLAY NEKLKKKYKY NSEVKRILRH RHLPKFIVKK
     KRVKQIQKIS KHKKMENVRS NNRIQDAPYI PERKKDLDVA QE
//