ID   J9RYK4_9BACT            Unreviewed;       746 AA.
AC   J9RYK4; Q4LCC8;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Conjugative transfer protein {ECO:0000313|EMBL:AFV47212.1};
DE   SubName: Full=DNA processing protein {ECO:0000313|EMBL:AFR44162.1};
DE   SubName: Full=DNA relaxase {ECO:0000313|EMBL:CAI10778.1};
GN   Name=traI {ECO:0000313|EMBL:AFR44162.1};
GN   ORFNames=pB8_044-1 {ECO:0000313|EMBL:CAI10778.1};
OS   uncultured bacterium.
OG   Plasmid pB8 {ECO:0000313|EMBL:CAI10778.1},
OG   Plasmid pKSP212 {ECO:0000313|EMBL:AFR44162.1}, and
OG   Plasmid pRWC72a {ECO:0000313|EMBL:AFV47212.1}.
OC   Bacteria; environmental samples.
OX   NCBI_TaxID=77133 {ECO:0000313|EMBL:AFR44162.1};
RN   [1] {ECO:0000313|EMBL:CAI10778.1}
RP   NUCLEOTIDE SEQUENCE.
RC   PLASMID=pB8 {ECO:0000313|EMBL:CAI10778.1};
RX   PubMed=16122561; DOI=10.1016/j.plasmid.2005.03.001;
RA   Schlueter A., Heuer H., Szczepanowski R., Poler S.M., Schneiker S.,
RA   Puehler A., Top E.M.;
RT   "Plasmid pB8 is closely related to the prototype IncP-1beta plasmid R751
RT   but transfers poorly to Escherichia coli and carries a new transposon
RT   encoding a small multidrug resistance efflux protein.";
RL   Plasmid 54:135-148(2005).
RN   [2] {ECO:0000313|EMBL:AFR44162.1}
RP   NUCLEOTIDE SEQUENCE.
RC   PLASMID=pKSP212 {ECO:0000313|EMBL:AFR44162.1};
RX   PubMed=22936717; DOI=10.1093/molbev/mss210;
RA   Sen D., Brown C.J., Top E.M., Sullivan J.;
RT   "Inferring the Evolutionary History of IncP-1 Plasmids Despite Incongruence
RT   among Backbone Gene Trees.";
RL   Mol. Biol. Evol. 30:154-166(2013).
RN   [3] {ECO:0000313|EMBL:AFV47212.1}
RP   NUCLEOTIDE SEQUENCE.
RC   PLASMID=pRWC72a {ECO:0000313|EMBL:AFV47212.1};
RX   PubMed=25389419; DOI=10.3389/fmicb.2014.00558;
RA   Rahube T.O., Viana L.S., Koraimann G., Yost C.K.;
RT   "Characterization and comparative analysis of antibiotic resistance
RT   plasmids isolated from a wastewater treatment plant.";
RL   Front. Microbiol. 5:558-558(2014).
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DR   EMBL; JX469831; AFR44162.1; -; Genomic_DNA.
DR   EMBL; JX486125; AFV47212.1; -; Genomic_DNA.
DR   EMBL; AJ863570; CAI10778.1; -; Genomic_DNA.
DR   AlphaFoldDB; J9RYK4; -.
DR   InterPro; IPR005094; Endonuclease_MobA/VirD2.
DR   InterPro; IPR040677; LPD7.
DR   InterPro; IPR049751; TraI/MobA_relaxases.
DR   NCBIfam; NF041893; TraI_MobP_relax; 1.
DR   Pfam; PF18821; LPD7; 1.
DR   Pfam; PF03432; Relaxase; 1.
PE   4: Predicted;
KW   Plasmid {ECO:0000313|EMBL:AFR44162.1}.
FT   DOMAIN          12..251
FT                   /note="MobA/VirD2-like nuclease"
FT                   /evidence="ECO:0000259|Pfam:PF03432"
FT   DOMAIN          422..509
FT                   /note="Large polyvalent protein-associated"
FT                   /evidence="ECO:0000259|Pfam:PF18821"
FT   REGION          510..594
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          624..652
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        510..528
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        559..585
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   746 AA;  82039 MW;  6CC57E73FDCC6A71 CRC64;
     MIAKHVPMRS LGKSDFAGLA NYITDAQSKD HRLGHVQATN CEAGSIQDAI TEVLATQHTN
     TRAKGDKTYH LIVSFRAGEQ PSADTLRAIE ERICVGLGYG EHQRISAVHN DTDNLHIHIA
     INKIHPTRHT MHEPYYPHRA LAELCTALER DYGLERDNHE PRKRGAEGRA ADMERHAGVE
     SLVGWIKREC LDEIKGAQSW QELHQVMRDN GMELRVRANG LVFEAGDGTM VKASTVARDL
     SKPSLEARLG PFEASPERQA QTTAKRQYRK DPIRLRVNTV ELYAKYKAEQ QSLTTARAQA
     LERARHRKDR LIEAAKRSNR LRRATIKVVG EGRANKKLLY AQASKALRSE IQAINKQFQQ
     ERTALYAEHS RRTWADWLKK EAQHGGADAL AALRAREAAQ GLKGNTIRGE GQAKPGHAPA
     VDNITKKGTI IFRAGMSAVR DDGDRLQVSR EATREGLQEA LRLAMQRYGN RITVNGTVEF
     KAQMIRAAVD SQLPITFTDP ALESRRQALL NKENTHERTE RPEHRGRTGR GAGGPGQRPA
     ADQHATGAAA VARAGDGRPA AGRGDRADAG LHAATVHRKP DVGRLGRKPP PQSQHRLRAL
     SELGVVRIAG GSEVLLPRDV PRHVEQQGTQ PDHALRRGIS RPGTGVGQTP PGVAAADKYI
     AEREAKRLKG FDIPKHSRYT AGDGALTFQG TRTIEGQALA LLKRGDEVMV MPIDQATARR
     LTRIAVGDAV SITAKGSIKT SKGRSR
//