ID J9USP2_BRAPL Unreviewed; 295 AA.
AC J9USP2;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Geranylgeranyl pyrophosphate synthase {ECO:0000313|EMBL:AFR70309.1};
GN ORFNames=B2904_orf966 {ECO:0000313|EMBL:AFR70309.1};
OS Brachyspira pilosicoli B2904.
OC Bacteria; Spirochaetota; Spirochaetia; Brachyspirales; Brachyspiraceae;
OC Brachyspira.
OX NCBI_TaxID=1133568 {ECO:0000313|EMBL:AFR70309.1, ECO:0000313|Proteomes:UP000007346};
RN [1] {ECO:0000313|EMBL:AFR70309.1, ECO:0000313|Proteomes:UP000007346}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B2904 {ECO:0000313|EMBL:AFR70309.1};
RX PubMed=22947175; DOI=10.1186/1471-2164-13-454;
RA Mappley L.J., Black M.L., Abuoun M., Darby A.C., Woodward M.J.,
RA Parkhill J., Turner A.K., Bellgard M.I., La T., Phillips N.D.,
RA La Ragione R.M., Hampson D.J.;
RT "Comparative genomics of Brachyspira pilosicoli strains: genome
RT rearrangements, reductions and correlation of genetic compliment with
RT phenotypic diversity.";
RL BMC Genomics 13:454-454(2012).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
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DR EMBL; CP003490; AFR70309.1; -; Genomic_DNA.
DR RefSeq; WP_014935705.1; NC_018607.1.
DR AlphaFoldDB; J9USP2; -.
DR KEGG; bpj:B2904_orf966; -.
DR PATRIC; fig|1133568.3.peg.965; -.
DR HOGENOM; CLU_014015_0_1_12; -.
DR Proteomes; UP000007346; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR43281; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR43281:SF1; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Transferase {ECO:0000256|RuleBase:RU004466}.
SQ SEQUENCE 295 AA; 33188 MW; 1B2A078B3C555C73 CRC64;
MNLKEYMNTR LKDIDSEINN IFKTINISLE NNFLDMLKYP LDAGGKRLRP ILTCLACELF
NGDYKKAIIP AVSLELIHTY SLVHDDLPAM DNDDLRRGKP TTHVKYGEAN AILVGDGLLT
HSFEILSNAN VNDKTLRKLL YEISYAAGVS GMVMGQFIDL YYEERDIDFE MLKILHSKKT
GAMIRGAVRV GAIASEKENI NLENITKYGE AIGLAFQIQD DILDVISDNE TLGKTVGKDE
KEGKLTYVKQ FGLEGAKEKA METSKEAIDY LNVYDDNEAK NILIELANYI VERKS
//
