ID J9VP84_CRYNH Unreviewed; 1149 AA.
AC J9VP84;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 2.
DT 22-FEB-2023, entry version 40.
DE SubName: Full=Cytoplasmic protein {ECO:0000313|EMBL:AFR96063.2};
GN ORFNames=CNAG_05745 {ECO:0000313|EMBL:AFR96063.2};
OS Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 /
OS CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=235443 {ECO:0000313|EMBL:AFR96063.2, ECO:0000313|Proteomes:UP000010091};
RN [1] {ECO:0000313|EMBL:AFR96063.2, ECO:0000313|Proteomes:UP000010091}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H99 / ATCC 208821 / CBS 10515 / FGSC 9487
RC {ECO:0000313|Proteomes:UP000010091};
RX PubMed=24743168; DOI=10.1371/journal.pgen.1004261;
RA Janbon G., Ormerod K.L., Paulet D., Byrnes E.J.III., Yadav V.,
RA Chatterjee G., Mullapudi N., Hon C.C., Billmyre R.B., Brunel F., Bahn Y.S.,
RA Chen W., Chen Y., Chow E.W., Coppee J.Y., Floyd-Averette A., Gaillardin C.,
RA Gerik K.J., Goldberg J., Gonzalez-Hilarion S., Gujja S., Hamlin J.L.,
RA Hsueh Y.P., Ianiri G., Jones S., Kodira C.D., Kozubowski L., Lam W.,
RA Marra M., Mesner L.D., Mieczkowski P.A., Moyrand F., Nielsen K., Proux C.,
RA Rossignol T., Schein J.E., Sun S., Wollschlaeger C., Wood I.A., Zeng Q.,
RA Neuveglise C., Newlon C.S., Perfect J.R., Lodge J.K., Idnurm A.,
RA Stajich J.E., Kronstad J.W., Sanyal K., Heitman J., Fraser J.A.,
RA Cuomo C.A., Dietrich F.S.;
RT "Analysis of the genome and transcriptome of Cryptococcus neoformans var.
RT grubii reveals complex RNA expression and microevolution leading to
RT virulence attenuation.";
RL PLoS Genet. 10:E1004261-E1004261(2014).
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DR EMBL; CP003826; AFR96063.2; -; Genomic_DNA.
DR RefSeq; XP_012050357.1; XM_012194967.1.
DR AlphaFoldDB; J9VP84; -.
DR GeneID; 23889038; -.
DR KEGG; cng:CNAG_05745; -.
DR VEuPathDB; FungiDB:CNAG_05745; -.
DR HOGENOM; CLU_269914_0_0_1; -.
DR OrthoDB; 5406906at2759; -.
DR Proteomes; UP000010091; Chromosome 7.
DR CDD; cd00072; GYF; 1.
DR Gene3D; 3.30.1490.40; -; 1.
DR InterPro; IPR003169; GYF.
DR InterPro; IPR035445; GYF-like_dom_sf.
DR PANTHER; PTHR14445:SF36; FI03272P-RELATED; 1.
DR PANTHER; PTHR14445; GRB10 INTERACTING GYF PROTEIN; 1.
DR Pfam; PF02213; GYF; 1.
DR SMART; SM00444; GYF; 1.
DR SUPFAM; SSF55277; GYF domain; 1.
DR PROSITE; PS50829; GYF; 1.
PE 4: Predicted;
FT DOMAIN 362..410
FT /note="GYF"
FT /evidence="ECO:0000259|PROSITE:PS50829"
FT REGION 1..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 160..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 235..263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 461..483
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 498..527
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 597..686
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 703..842
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 860..999
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1106..1149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 13..75
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 160..180
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 468..482
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 511..527
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 597..664
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 670..686
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 721..751
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 797..811
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 828..842
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 861..899
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 916..932
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1149 AA; 121400 MW; C5FE0022AE9CA1C8 CRC64;
MSMHFAPQWA KPIKPSGSTT TTPTTEVPVR KSTTSSPFPA LSANPSSASP TTTTHPTLSY
SRVTHTPSSP NVATDGYFPN QDLNGGMVNP HPFRYSREQI LSLFDESKFK ERPIELVEMA
EGGGVLVSQS VNRPVGMRDL TDAEKKILAT SVHPALSTRR QLNQTNTSGE HVTNGLPTRR
NAGFTRGEGG AFSGSLGKMG SFGGGVLSPG GIDHKAPGAL GGGFGGVAKR MSRRNEDFGG
ESRSSAATWR SGPKTPAGNF EGVLGFNNSA APLSPSVETS EQKEVGQRKW RIAAGLPTGE
SDKTLDVPIS NQAGASASVI ATPSATPIPD RDATVLDSTP APAPSSQTPH APIQEPKEDL
GAVEWFYRDP NGQEQGPFTG TQMHDWYSHS YFTDDLPLRR ASENGFRPLS ELKAATGNAV
QPFLSPIRPR QLPPNLPIPI AALQQHAMSS LPDNFRNLSV QSPIGSDPRV SPQPPLPSVP
GAAPYIPGYD TAFPHSYPLG HQPLDQVASP GYAPSPTQGW NALSPQPSLR MGMSPLSPAP
FSNITVPSPI GSAPLQYMQQ QQQQPQQHQG YFGAPQQMGM RSASGDIYVQ PQPWGMQGLQ
QQAGGFPQQM GYQPQPQSHP QSQSTPVQWD QPQVPQQVLP QQIQPQQQQE VEQRVPVSEP
VNEESQSEQV EETAEVKIPT EPKSEADLQL ETVEDVKEQV AINLEQEEED EVEELTPVES
PVISTPASKP TPAPTTSAWK KTQTPSGEAS LADSVGPTPA QAASIKSSKP ISREESIEII
PTPAQLPKVV DVSTPGPTAD ASASPSLERS SSKPKIAPWA IKNEERVAPS PSLRDIQEAE
AKRAEARRVA LAEARAATAS PVLVSASSED LPASMSWGLP SQTGKGTVRS HSPAAPTTPS
SAVAAWGGAG EAPKKTLKQI QEEEEKRKTR AAQAARVAQG QAAGVGASAV PGAGSTRRGY
ADLAAAPVKK EETQPGWTTV GAGGRVASSS GVPRAATPVN VKPTPAPIVK PVATPVSVKK
TTGPSASIAD DGAPSVEFIR WTKRALTGFK GDVDDFISVL LSFPIDPPAA SRADQMEIIS
DSVYANSSTL DGRRFAQEFM AKRKADAARP GGAAGGKKIS SLADVVKTQP KQTSDAGFKV
VKAKGKKKN
//
