ID J9W255_CRYNH Unreviewed; 348 AA.
AC J9W255;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=OTU domain-containing protein 6B {ECO:0000313|EMBL:AFR98200.1};
GN ORFNames=CNAG_02004 {ECO:0000313|EMBL:AFR98200.1};
OS Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 /
OS CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=235443 {ECO:0000313|EMBL:AFR98200.1, ECO:0000313|Proteomes:UP000010091};
RN [1] {ECO:0000313|EMBL:AFR98200.1, ECO:0000313|Proteomes:UP000010091}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H99 / ATCC 208821 / CBS 10515 / FGSC 9487
RC {ECO:0000313|Proteomes:UP000010091};
RX PubMed=24743168; DOI=10.1371/journal.pgen.1004261;
RA Janbon G., Ormerod K.L., Paulet D., Byrnes E.J.III., Yadav V.,
RA Chatterjee G., Mullapudi N., Hon C.C., Billmyre R.B., Brunel F., Bahn Y.S.,
RA Chen W., Chen Y., Chow E.W., Coppee J.Y., Floyd-Averette A., Gaillardin C.,
RA Gerik K.J., Goldberg J., Gonzalez-Hilarion S., Gujja S., Hamlin J.L.,
RA Hsueh Y.P., Ianiri G., Jones S., Kodira C.D., Kozubowski L., Lam W.,
RA Marra M., Mesner L.D., Mieczkowski P.A., Moyrand F., Nielsen K., Proux C.,
RA Rossignol T., Schein J.E., Sun S., Wollschlaeger C., Wood I.A., Zeng Q.,
RA Neuveglise C., Newlon C.S., Perfect J.R., Lodge J.K., Idnurm A.,
RA Stajich J.E., Kronstad J.W., Sanyal K., Heitman J., Fraser J.A.,
RA Cuomo C.A., Dietrich F.S.;
RT "Analysis of the genome and transcriptome of Cryptococcus neoformans var.
RT grubii reveals complex RNA expression and microevolution leading to
RT virulence attenuation.";
RL PLoS Genet. 10:E1004261-E1004261(2014).
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DR EMBL; CP003830; AFR98200.1; -; Genomic_DNA.
DR RefSeq; XP_012052900.1; XM_012197510.1.
DR AlphaFoldDB; J9W255; -.
DR GeneID; 23885666; -.
DR KEGG; cng:CNAG_02004; -.
DR VEuPathDB; FungiDB:CNAG_02004; -.
DR HOGENOM; CLU_034963_1_0_1; -.
DR OrthoDB; 242020at2759; -.
DR Proteomes; UP000010091; Chromosome 11.
DR GO; GO:0019538; P:protein metabolic process; IEA:UniProt.
DR CDD; cd22748; OTU_OTUD6-like; 1.
DR Gene3D; 3.90.70.80; -; 1.
DR InterPro; IPR003323; OTU_dom.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR PANTHER; PTHR12419:SF10; DEUBIQUITINASE OTUD6B; 1.
DR PANTHER; PTHR12419; OTU DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF02338; OTU; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS50802; OTU; 1.
PE 4: Predicted;
FT DOMAIN 181..347
FT /note="OTU"
FT /evidence="ECO:0000259|PROSITE:PS50802"
FT REGION 1..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 296..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..35
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..81
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 90..107
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..144
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 348 AA; 36874 MW; 23829FDE322DFFB7 CRC64;
MPGSKRRALK KLLSPNHSPL APDSPSADTT PTSALSPQPE LPPATDDAAA AQAAAAGISP
QELQDNAVLE DMHEREKEIG HASAPAGLGG VISPSSSSAS TQETKSGGMY GGGMYANANG
GGGGGKKKKS SRQRFEERQA RKQEALLEST PPADPGWTAQ LEKERQEEIK VISDACFALN
RDLFEIAPDG HCMYAAIGDQ LGLLGIIPAE EATNPRAIRR KAADYMLSHP DDFMPFLPSI
TGEDTPDATS DGMITPSGFA QYCKAVAETG EWGGEPEIQA LSRAYEIPIH VIQRGPPTVV
SHGGKDDSFG GGLTAEESSK QGERVVRISY HKRMYGLGEH YNSLRPVA
//
