ID K0JK17_BRAPL Unreviewed; 569 AA.
AC K0JK17;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Thiol disulfide interchange protein {ECO:0000313|EMBL:CCG56650.1};
GN Name=dsbD {ECO:0000313|EMBL:CCG56650.1};
GN ORFNames=WESB_1181 {ECO:0000313|EMBL:CCG56650.1};
OS Brachyspira pilosicoli WesB.
OC Bacteria; Spirochaetota; Spirochaetia; Brachyspirales; Brachyspiraceae;
OC Brachyspira.
OX NCBI_TaxID=1161918 {ECO:0000313|EMBL:CCG56650.1, ECO:0000313|Proteomes:UP000003759};
RN [1] {ECO:0000313|EMBL:CCG56650.1, ECO:0000313|Proteomes:UP000003759}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WesB {ECO:0000313|EMBL:CCG56650.1};
RX PubMed=22947175; DOI=10.1186/1471-2164-13-454;
RA Mappley L.J., Black M.L., Abuoun M., Darby A.C., Woodward M.J.,
RA Parkhill J., Turner A.K., Bellgard M.I., La T., Phillips N.D.,
RA La Ragione R.M., Hampson D.J.;
RT "Comparative genomics of Brachyspira pilosicoli strains: genome
RT rearrangements, reductions and correlation of genetic compliment with
RT phenotypic diversity.";
RL BMC Genomics 13:454-454(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; HE793032; CCG56650.1; -; Genomic_DNA.
DR RefSeq; WP_014932983.1; NC_018604.1.
DR AlphaFoldDB; K0JK17; -.
DR KEGG; bpw:WESB_1181; -.
DR PATRIC; fig|1161918.5.peg.485; -.
DR HOGENOM; CLU_015841_0_0_12; -.
DR OrthoDB; 7629852at2; -.
DR Proteomes; UP000003759; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:InterPro.
DR CDD; cd02947; TRX_family; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR003834; Cyt_c_assmbl_TM_dom.
DR InterPro; IPR036929; DsbDN_sf.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR32234:SF3; SUPPRESSION OF COPPER SENSITIVITY PROTEIN; 1.
DR PANTHER; PTHR32234; THIOL:DISULFIDE INTERCHANGE PROTEIN DSBD; 1.
DR Pfam; PF02683; DsbD; 1.
DR Pfam; PF13899; Thioredoxin_7; 1.
DR SUPFAM; SSF74863; Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha); 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 165..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..237
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 249..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 299..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..356
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 368..385
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 397..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 428..448
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 430..568
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
SQ SEQUENCE 569 AA; 63942 MW; 1A75F2C91ED8F4E7 CRC64;
MRKIYIFLFI IFSLTAYSQS FNSLLNKNTE AIIVFSLSTN DNKITVKANI PEGYYAYLES
KIANKILFFA DNKEINTTYP EGEKYHEDII IKGEQEFILN DIDINKINFI KTTYQLCSAK
DNVCLQPKSK VIYGEEIDIP NNNITDEKPE NASSIENYIK GSNNIFITLI LIFAAGLASV
LLPCTYPLLS ITVSILGTTT DEKNNKKSSV LASLLFALGV ITTYTLLGAV VSVAGFAFHK
TILFGSIGYN PIVLTILVLL FLYFTFSMAG FYEIKAPSFL QSAKTNAYAK KNQSIFHKYI
MGLLAGIVAT PCAAPIIAVI LEIGFLNPVF ATLYMAVYAL GFASVLFILG TFASILTKMP
KAGTWMVYVK YIFTFLMMII SFYYANILFG VLGFNKISYI LASVTILVFA LLVYIIKNKT
AMLSSLEKKI FVSVLIISIV LGSIYGIIKQ KSEVSNLVTY NEALELSKQN NKPILIDFSA
VWCANCYELK EKVFVNEELK KFIDDNLIFT EVDVDKYKNI SDEYNVKWLP WIIVIDSDKN
ILYTKNSFSS FDDKMALSIK EDLEKVINK
//
