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Database: UniProt
Entry: K0JKP3_BRAPL
LinkDB: K0JKP3_BRAPL
Original site: K0JKP3_BRAPL 
ID   K0JKP3_BRAPL            Unreviewed;       158 AA.
AC   K0JKP3;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   24-JAN-2024, entry version 44.
DE   RecName: Full=Manganese transport regulator {ECO:0000256|ARBA:ARBA00032593};
GN   ORFNames=WESB_1293 {ECO:0000313|EMBL:CCG56761.1};
OS   Brachyspira pilosicoli WesB.
OC   Bacteria; Spirochaetota; Spirochaetia; Brachyspirales; Brachyspiraceae;
OC   Brachyspira.
OX   NCBI_TaxID=1161918 {ECO:0000313|EMBL:CCG56761.1, ECO:0000313|Proteomes:UP000003759};
RN   [1] {ECO:0000313|EMBL:CCG56761.1, ECO:0000313|Proteomes:UP000003759}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WesB {ECO:0000313|EMBL:CCG56761.1};
RX   PubMed=22947175; DOI=10.1186/1471-2164-13-454;
RA   Mappley L.J., Black M.L., Abuoun M., Darby A.C., Woodward M.J.,
RA   Parkhill J., Turner A.K., Bellgard M.I., La T., Phillips N.D.,
RA   La Ragione R.M., Hampson D.J.;
RT   "Comparative genomics of Brachyspira pilosicoli strains: genome
RT   rearrangements, reductions and correlation of genetic compliment with
RT   phenotypic diversity.";
RL   BMC Genomics 13:454-454(2012).
CC   -!- SIMILARITY: Belongs to the DtxR/MntR family.
CC       {ECO:0000256|ARBA:ARBA00007871}.
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DR   EMBL; HE793032; CCG56761.1; -; Genomic_DNA.
DR   AlphaFoldDB; K0JKP3; -.
DR   KEGG; bpw:WESB_1293; -.
DR   PATRIC; fig|1161918.5.peg.600; -.
DR   HOGENOM; CLU_069532_3_0_12; -.
DR   Proteomes; UP000003759; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0046914; F:transition metal ion binding; IEA:InterPro.
DR   Gene3D; 1.10.60.10; Iron dependent repressor, metal binding and dimerisation domain; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR001367; Fe_dep_repressor.
DR   InterPro; IPR036421; Fe_dep_repressor_sf.
DR   InterPro; IPR022687; HTH_DTXR.
DR   InterPro; IPR022689; Iron_dep_repressor.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR33238; IRON (METAL) DEPENDENT REPRESSOR, DTXR FAMILY; 1.
DR   PANTHER; PTHR33238:SF7; TRANSCRIPTIONAL REGULATOR MNTR; 1.
DR   Pfam; PF02742; Fe_dep_repr_C; 1.
DR   Pfam; PF01325; Fe_dep_repress; 1.
DR   SMART; SM00529; HTH_DTXR; 1.
DR   SUPFAM; SSF47979; Iron-dependent repressor protein, dimerization domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50944; HTH_DTXR; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          25..89
FT                   /note="HTH dtxR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50944"
SQ   SEQUENCE   158 AA;  18661 MW;  C32033CB0FD3CB49 CRC64;
     MKNYVFYIDL YIFYIKIIRM RQQEMTPILE NYLETIYNLE VEKKFKEAIR ITDIADLVGR
     SKASVNTAIK TLSKLGHIKH EHYGDIELTD SGRAIGKDIA ERHAIFYYFL TKVLNIDEKI
     ADEEACLIEH AMSRDTVHKF KEFLCDYCKK ENILNKQN
//
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