ID K0JYC3_SACES Unreviewed; 500 AA.
AC K0JYC3;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=AMP-dependent synthetase and ligase {ECO:0000313|EMBL:CCH31121.1};
GN OrderedLocusNames=BN6_38310 {ECO:0000313|EMBL:CCH31121.1};
OS Saccharothrix espanaensis (strain ATCC 51144 / DSM 44229 / JCM 9112 / NBRC
OS 15066 / NRRL 15764).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=1179773 {ECO:0000313|EMBL:CCH31121.1, ECO:0000313|Proteomes:UP000006281};
RN [1] {ECO:0000313|EMBL:CCH31121.1, ECO:0000313|Proteomes:UP000006281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51144 / DSM 44229 / JCM 9112 / NBRC 15066 / NRRL 15764
RC {ECO:0000313|Proteomes:UP000006281};
RX PubMed=22958348; DOI=10.1186/1471-2164-13-465;
RA Strobel T., Al-Dilaimi A., Blom J., Gessner A., Kalinowski J.,
RA Luzhetska M., Puhler A., Szczepanowski R., Bechthold A., Ruckert C.;
RT "Complete genome sequence of Saccharothrix espanaensis DSM 44229T and
RT comparison to the other completely sequenced Pseudonocardiaceae.";
RL BMC Genomics 13:465-465(2012).
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DR EMBL; HE804045; CCH31121.1; -; Genomic_DNA.
DR AlphaFoldDB; K0JYC3; -.
DR STRING; 1179773.BN6_38310; -.
DR KEGG; sesp:BN6_38310; -.
DR PATRIC; fig|1179773.3.peg.3831; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_10_11; -.
DR OrthoDB; 5240965at2; -.
DR BioCyc; SESP1179773:BN6_RS18545-MONOMER; -.
DR Proteomes; UP000006281; Chromosome.
DR GO; GO:0016877; F:ligase activity, forming carbon-sulfur bonds; IEA:UniProt.
DR CDD; cd04433; AFD_class_I; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF1; NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:CCH31121.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006281}.
FT DOMAIN 11..369
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 413..482
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 500 AA; 52492 MW; 552B51FBA6A83738 CRC64;
MPDDLLLEVL RAAREHGPRP ALTDARGRTS TYRELSDRVL GTAHRLRAEG MRTGTRMLFS
VRPGPDAIVL ALGTVAAGGT VVFIDPGVGP ELFASRFALA DPGWAAAESL LYAASAPGPL
RALARRRGVL LPNYGRLPLR HIRSGPWLPG VPVRAVSTRS LFRAVPGAVP PDPDPDQEAV
VVFTSGTTAT PKAVVHTRGS LGAALRTLAT RCELGPDTRV HTDQMMLGLP ALVAGAHWTM
PPYGFAPSAD PAAVAAGLAG ATHTFLVPAD LAVILDSGVA LPGSLRQVLL GSAPVLPPLL
KRAQRALPDV EFLAVYGMTE ILPVAIATAD EKIGHGGDLL GRPLPGVSAR LAPDGELLVS
GPNLCRGYLG EPPLTEHATG DLARWDDDRL VLTGRKKDMI IRGRTNVYPG LYEPAIADLP
GVAGAVMVGV PDAIGDERIV LVLTALPGTS AGLAQRVRAA LPDLIDASAL PDEVVLVDEL
PLAGRLRKID RTALRERFAR
//
