ID K0K4C6_SACES Unreviewed; 286 AA.
AC K0K4C6;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=6-phosphogluconate dehydrogenase {ECO:0000313|EMBL:CCH35085.1};
GN OrderedLocusNames=BN6_78670 {ECO:0000313|EMBL:CCH35085.1};
OS Saccharothrix espanaensis (strain ATCC 51144 / DSM 44229 / JCM 9112 / NBRC
OS 15066 / NRRL 15764).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=1179773 {ECO:0000313|EMBL:CCH35085.1, ECO:0000313|Proteomes:UP000006281};
RN [1] {ECO:0000313|EMBL:CCH35085.1, ECO:0000313|Proteomes:UP000006281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51144 / DSM 44229 / JCM 9112 / NBRC 15066 / NRRL 15764
RC {ECO:0000313|Proteomes:UP000006281};
RX PubMed=22958348; DOI=10.1186/1471-2164-13-465;
RA Strobel T., Al-Dilaimi A., Blom J., Gessner A., Kalinowski J.,
RA Luzhetska M., Puhler A., Szczepanowski R., Bechthold A., Ruckert C.;
RT "Complete genome sequence of Saccharothrix espanaensis DSM 44229T and
RT comparison to the other completely sequenced Pseudonocardiaceae.";
RL BMC Genomics 13:465-465(2012).
CC -!- SIMILARITY: Belongs to the HIBADH-related family.
CC {ECO:0000256|ARBA:ARBA00009080}.
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DR EMBL; HE804045; CCH35085.1; -; Genomic_DNA.
DR RefSeq; WP_015105194.1; NC_019673.1.
DR AlphaFoldDB; K0K4C6; -.
DR SMR; K0K4C6; -.
DR STRING; 1179773.BN6_78670; -.
DR KEGG; sesp:BN6_78670; -.
DR PATRIC; fig|1179773.3.peg.7942; -.
DR eggNOG; COG2084; Bacteria.
DR HOGENOM; CLU_035117_2_1_11; -.
DR OrthoDB; 9135493at2; -.
DR BioCyc; SESP1179773:BN6_RS38045-MONOMER; -.
DR Proteomes; UP000006281; Chromosome.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR048666; RedAm-like_C.
DR PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR PANTHER; PTHR43580:SF2; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR Pfam; PF21761; RedAm-like_C; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006281}.
FT DOMAIN 6..152
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 158..283
FT /note="NADPH-dependent reductive aminase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21761"
SQ SEQUENCE 286 AA; 30538 MW; CD8B7338BC225D00 CRC64;
MSTPLTLIGL GPMGQAMVAK YLEHGHPVTV WNRTASRADD LVARGAVRAD TPRDAVAANR
LVVLSLTDYQ AMYDVLGDAE LAGKTVVNLS SDTPDKTLKA AAWLAERGAE LVVGGVMVPA
PLVGEEAAYV FYSGPKAVFE QHAEVLAVIG RTEYLGEDHA LAQLFYQAQL DFFLTTLAAT
LHSVALVRTA GVTAAQFAPY LKDNAESIWM YLEETITAVD RGEHPGDLAN IVMMGATADH
VVGASEATGV DAGLPRAVQD MYRRAIEAGH GQESWTALYE VIKPAK
//
