ID K0K4S9_SACES Unreviewed; 344 AA.
AC K0K4S9;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=SGNH hydrolase-type esterase domain-containing protein {ECO:0000259|Pfam:PF13472};
GN OrderedLocusNames=BN6_60520 {ECO:0000313|EMBL:CCH33306.1};
OS Saccharothrix espanaensis (strain ATCC 51144 / DSM 44229 / JCM 9112 / NBRC
OS 15066 / NRRL 15764).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=1179773 {ECO:0000313|EMBL:CCH33306.1, ECO:0000313|Proteomes:UP000006281};
RN [1] {ECO:0000313|EMBL:CCH33306.1, ECO:0000313|Proteomes:UP000006281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51144 / DSM 44229 / JCM 9112 / NBRC 15066 / NRRL 15764
RC {ECO:0000313|Proteomes:UP000006281};
RX PubMed=22958348; DOI=10.1186/1471-2164-13-465;
RA Strobel T., Al-Dilaimi A., Blom J., Gessner A., Kalinowski J.,
RA Luzhetska M., Puhler A., Szczepanowski R., Bechthold A., Ruckert C.;
RT "Complete genome sequence of Saccharothrix espanaensis DSM 44229T and
RT comparison to the other completely sequenced Pseudonocardiaceae.";
RL BMC Genomics 13:465-465(2012).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; HE804045; CCH33306.1; -; Genomic_DNA.
DR RefSeq; WP_015103417.1; NC_019673.1.
DR AlphaFoldDB; K0K4S9; -.
DR STRING; 1179773.BN6_60520; -.
DR KEGG; sesp:BN6_60520; -.
DR PATRIC; fig|1179773.3.peg.6095; -.
DR eggNOG; COG2755; Bacteria.
DR HOGENOM; CLU_055979_0_0_11; -.
DR OrthoDB; 3498399at2; -.
DR BioCyc; SESP1179773:BN6_RS29120-MONOMER; -.
DR Proteomes; UP000006281; Chromosome.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR Gene3D; 3.40.50.1110; SGNH hydrolase; 1.
DR InterPro; IPR037460; SEST-like.
DR InterPro; IPR013830; SGNH_hydro.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR PANTHER; PTHR37981; LIPASE 2; 1.
DR PANTHER; PTHR37981:SF1; SGNH_HYDRO DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13472; Lipase_GDSL_2; 1.
DR SUPFAM; SSF52266; SGNH hydrolase; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR637460-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000006281};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..344
FT /note="SGNH hydrolase-type esterase domain-containing
FT protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5038914602"
FT DOMAIN 42..310
FT /note="SGNH hydrolase-type esterase"
FT /evidence="ECO:0000259|Pfam:PF13472"
FT ACT_SITE 46
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-1"
FT ACT_SITE 303
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-1"
FT DISULFID 68..92
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-2"
FT DISULFID 146..156
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-2"
SQ SEQUENCE 344 AA; 37336 MW; 546BA7097F0D6CC6 CRC64;
MLRRSLALAL VLPLLAVLLM VADSPFPDPL GPNRDAPAAL VALGDSTMSG EGAGSYEPGT
DGENDNWCHR STKASVRQTR VAGVEKVFNL ACSGTSAEQV GLGDGTDRSS QARQLAEIAR
EYRVTTVVVA MGANDDPKFG EVLSSCLRAW FERADCSKAL ADEWRERVDR MVPKVERALR
DIRLALRDEG YTPLSYTLVV QSYAAPVSPD LPSDLQNLAG CPLRTADMRW VRDTAVGDLS
DGLRKAASAV GARFLDLSRA GAKHEACAGG KNPDSEWFTR LTVDFDGLRD EVRARHALQE
SFHPNARGHE QFGRCMTEFL ATSAREASCV ADRDGNLTPV LDRD
//
