ID K0KNU5_WICCF Unreviewed; 444 AA.
AC K0KNU5;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE SubName: Full=Beclin-1 {ECO:0000313|EMBL:CCH43847.1};
GN ORFNames=BN7_3401 {ECO:0000313|EMBL:CCH43847.1};
OS Wickerhamomyces ciferrii (strain ATCC 14091 / BCRC 22168 / CBS 111 / JCM
OS 3599 / NBRC 0793 / NRRL Y-1031 F-60-10) (Yeast) (Pichia ciferrii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Phaffomycetaceae; Wickerhamomyces.
OX NCBI_TaxID=1206466 {ECO:0000313|EMBL:CCH43847.1, ECO:0000313|Proteomes:UP000009328};
RN [1] {ECO:0000313|EMBL:CCH43847.1, ECO:0000313|Proteomes:UP000009328}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14091 / BCRC 22168 / CBS 111 / JCM 3599 / NBRC 0793 / NRRL
RC Y-1031 F-60-10 {ECO:0000313|Proteomes:UP000009328};
RX PubMed=23193139; DOI=10.1128/EC.00258-12;
RA Schneider J., Andrea H., Blom J., Jaenicke S., Ruckert C., Schorsch C.,
RA Szczepanowski R., Farwick M., Goesmann A., Puhler A., Schaffer S.,
RA Tauch A., Kohler T., Brinkrolf K.;
RT "Draft genome sequence of Wickerhamomyces ciferrii NRRL Y-1031 F-60-10.";
RL Eukaryot. Cell 11:1582-1583(2012).
CC -!- SIMILARITY: Belongs to the beclin family.
CC {ECO:0000256|ARBA:ARBA00005965}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCH43847.1}.
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DR EMBL; CAIF01000091; CCH43847.1; -; Genomic_DNA.
DR AlphaFoldDB; K0KNU5; -.
DR STRING; 1206466.K0KNU5; -.
DR eggNOG; KOG2751; Eukaryota.
DR HOGENOM; CLU_024219_3_0_1; -.
DR InParanoid; K0KNU5; -.
DR Proteomes; UP000009328; Unassembled WGS sequence.
DR GO; GO:0006914; P:autophagy; IEA:InterPro.
DR Gene3D; 6.10.250.3110; -; 1.
DR Gene3D; 1.10.418.40; Autophagy protein 6/Beclin 1; 1.
DR InterPro; IPR007243; Atg6/Beclin.
DR InterPro; IPR038274; Atg6/Beclin_C_sf.
DR InterPro; IPR041691; Atg6/beclin_CC.
DR InterPro; IPR040455; Atg6_BARA.
DR PANTHER; PTHR12768; BECLIN 1; 1.
DR PANTHER; PTHR12768:SF4; BECLIN-1; 1.
DR Pfam; PF04111; APG6; 1.
DR Pfam; PF17675; APG6_N; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000009328}.
FT DOMAIN 138..267
FT /note="Atg6/beclin coiled-coil"
FT /evidence="ECO:0000259|Pfam:PF17675"
FT DOMAIN 270..443
FT /note="Atg6 BARA"
FT /evidence="ECO:0000259|Pfam:PF04111"
FT REGION 32..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 180..259
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 32..49
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 444 AA; 50346 MW; D36C83E263604AF1 CRC64;
MSPTNHCHRC KLPIIIDPSL INLTKAQSSL LTSGRNGFGK GNSTSKETEL GDEPFIPKER
SDLLQKATQS SKNQAQFPKK SYEATDSFVI LSQFENDESE ENGVDSDIDI DNKTLSNRLN
TLSNIFNVLS SKNEIDYPVC KDCAQLLLTQ LKIKYDKSVK EREVYMQFLS KLQDKQAPVV
EKSQESIDEM NKLANQENEL LEELKALEKE NDDLDDEIKT VTEEIKNIDL QEQQMYKEEN
EKELEIRNVL NEKDAIKAEY DFNVSQLEKL RKTNVYNDTF NISHDGPFGT INGLRLGSLE
STKVPWQEIN AALGHLVLLM ATVSARLNFK LQGYKLKPMG STSKIEKFER DLSNPSKPKV
TVLEVYSSGE YQIERLFTHS KLDNALVALL EIVSQIANKL KELDPSIDLP YKMIKDKIGD
ASIRLSSKTA SEEWTGACKF LLTK
//
