ID K0RK90_THAOC Unreviewed; 768 AA.
AC K0RK90;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Inosine/uridine-preferring nucleoside hydrolase domain-containing protein {ECO:0000259|Pfam:PF01156};
GN ORFNames=THAOC_26301 {ECO:0000313|EMBL:EJK54138.1};
OS Thalassiosira oceanica (Marine diatom).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Coscinodiscophyceae; Thalassiosirophycidae; Thalassiosirales;
OC Thalassiosiraceae; Thalassiosira.
OX NCBI_TaxID=159749 {ECO:0000313|EMBL:EJK54138.1, ECO:0000313|Proteomes:UP000266841};
RN [1] {ECO:0000313|EMBL:EJK54138.1, ECO:0000313|Proteomes:UP000266841}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1005 {ECO:0000313|EMBL:EJK54138.1,
RC ECO:0000313|Proteomes:UP000266841};
RX PubMed=22835381; DOI=10.1186/gb-2012-13-7-r66;
RA Lommer M., Specht M., Roy A.S., Kraemer L., Andreson R., Gutowska M.A.,
RA Wolf J., Bergner S.V., Schilhabel M.B., Klostermeier U.C., Beiko R.G.,
RA Rosenstiel P., Hippler M., Laroche J.;
RT "Genome and low-iron response of an oceanic diatom adapted to chronic iron
RT limitation.";
RL Genome Biol. 13:R66-R66(2012).
CC -!- SIMILARITY: Belongs to the IUNH family.
CC {ECO:0000256|ARBA:ARBA00009176}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJK54138.1}.
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DR EMBL; AGNL01036306; EJK54138.1; -; Genomic_DNA.
DR AlphaFoldDB; K0RK90; -.
DR EnsemblProtists; EJK54138; EJK54138; THAOC_26301.
DR eggNOG; KOG1840; Eukaryota.
DR Proteomes; UP000266841; Unassembled WGS sequence.
DR GO; GO:0016799; F:hydrolase activity, hydrolyzing N-glycosyl compounds; IEA:InterPro.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:UniProt.
DR GO; GO:1901564; P:organonitrogen compound metabolic process; IEA:UniProt.
DR Gene3D; 3.90.245.10; Ribonucleoside hydrolase-like; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR001910; Inosine/uridine_hydrolase_dom.
DR InterPro; IPR036452; Ribo_hydro-like.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45641:SF20; PUB DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45641; TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870); 1.
DR Pfam; PF01156; IU_nuc_hydro; 1.
DR Pfam; PF13374; TPR_10; 1.
DR Pfam; PF13424; TPR_12; 2.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF53590; Nucleoside hydrolase; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000266841};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803}.
FT DOMAIN 401..637
FT /note="Inosine/uridine-preferring nucleoside hydrolase"
FT /evidence="ECO:0000259|Pfam:PF01156"
SQ SEQUENCE 768 AA; 85107 MW; 37BE2AE5BB6F1948 CRC64;
MKSQADTAAS TAASSVATGL KKRRMSFDDF MVAGDTAAGS LKYTEAIDLY NEAMQRAPRR
LEPNLKLGSC LREMARYRES EKILLACIDG KSQQLALNPE LHLRALQSLA ALYQAQSKYE
SAIKIHVRAV SMARSIEGLN RICLANTLSG YAETLRKSGG FPSAEKYHRE ALEIRTLAVT
EGAVSELELA VSYTQLGCTL SAIEKAHESY EQHRMALTLR YRYLDFSHGL VSESLNYCAA
NLSRLRRGEE GIPLALHALQ IRKSLFGVRH PAYAHTLSVL ASCYHAVGRY LDACDCLERC
LEICEVAFQK NHANIIPNLM NYGDVLRSLG HLDKAKSVFE RAISIHELHF KAGQLDRQLS
KCKIQVKMLA DELKDKISSS SAMSGGSVDE VDYQPGPGTP VIVITDIGRD VDDEMALVLL
SSLKRKRTLN PIAVVTTLAP QEDRANLARG SLDTLALAAV PVGVGGRGGL DEKVDLEVYA
AEHSTFPHAS IHDSGIELML DALEQAEPKT VRVLILASMS DVAEILEQHE DIFVEKVSEV
IIMGGVEPIL SSDFLTPDTA YNNNCDMESA KLVYTKCQEL RIPTVTLSRW AAYGCPVRPC
LLDELAKTKH MIASNIQRMS KHSLDQLWRK VILPDNHPGR EKLPSRCNTQ WFMETFCDSN
EIPNPLPDSP WTQVTKLNMY DPLAVLVCCP SYRDAHFYWQ SKYVDGVEHK VIGSSNQTGV
KDSCRLYSEY SSLFLDALKS AMKQPELPLG REKDTDLIAS SVHLNRAA
//
