ID   K0RM32_THAOC            Unreviewed;       721 AA.
AC   K0RM32;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   RecName: Full=Peptidase S1 domain-containing protein {ECO:0000259|PROSITE:PS50240};
DE   Flags: Fragment;
GN   ORFNames=THAOC_25591 {ECO:0000313|EMBL:EJK54753.1};
OS   Thalassiosira oceanica (Marine diatom).
OC   Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC   Coscinodiscophyceae; Thalassiosirophycidae; Thalassiosirales;
OC   Thalassiosiraceae; Thalassiosira.
OX   NCBI_TaxID=159749 {ECO:0000313|EMBL:EJK54753.1, ECO:0000313|Proteomes:UP000266841};
RN   [1] {ECO:0000313|EMBL:EJK54753.1, ECO:0000313|Proteomes:UP000266841}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCMP1005 {ECO:0000313|EMBL:EJK54753.1,
RC   ECO:0000313|Proteomes:UP000266841};
RX   PubMed=22835381; DOI=10.1186/gb-2012-13-7-r66;
RA   Lommer M., Specht M., Roy A.S., Kraemer L., Andreson R., Gutowska M.A.,
RA   Wolf J., Bergner S.V., Schilhabel M.B., Klostermeier U.C., Beiko R.G.,
RA   Rosenstiel P., Hippler M., Laroche J.;
RT   "Genome and low-iron response of an oceanic diatom adapted to chronic iron
RT   limitation.";
RL   Genome Biol. 13:R66-R66(2012).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the peptidase S1 family.
CC       {ECO:0000256|ARBA:ARBA00007664}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJK54753.1}.
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DR   EMBL; AGNL01035335; EJK54753.1; -; Genomic_DNA.
DR   AlphaFoldDB; K0RM32; -.
DR   EnsemblProtists; EJK54753; EJK54753; THAOC_25591.
DR   eggNOG; KOG3627; Eukaryota.
DR   Proteomes; UP000266841; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR   InterPro; IPR001254; Trypsin_dom.
DR   InterPro; IPR018114; TRYPSIN_HIS.
DR   PANTHER; PTHR24276:SF91; AT26814P-RELATED; 1.
DR   PANTHER; PTHR24276; POLYSERASE-RELATED; 1.
DR   Pfam; PF00089; Trypsin; 2.
DR   SMART; SM00020; Tryp_SPc; 1.
DR   SUPFAM; SSF50494; Trypsin-like serine proteases; 2.
DR   PROSITE; PS50240; TRYPSIN_DOM; 2.
DR   PROSITE; PS00134; TRYPSIN_HIS; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000266841};
KW   Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT   DOMAIN          211..355
FT                   /note="Peptidase S1"
FT                   /evidence="ECO:0000259|PROSITE:PS50240"
FT   DOMAIN          386..676
FT                   /note="Peptidase S1"
FT                   /evidence="ECO:0000259|PROSITE:PS50240"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        11..26
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         721
FT                   /evidence="ECO:0000313|EMBL:EJK54753.1"
SQ   SEQUENCE   721 AA;  78532 MW;  7557FC672D00CFC7 CRC64;
     MTTAAPAPAG DDRGHRGEEA TAKTRTDIIL ADRHSGNDRR EKEKGAWTTA WTRGSLGARV
     ARARTMAAAA MPVVANARSV ASILTSTDGF HLSRAGMELH SPLNYKSLEH EFRRQRRLKV
     KDDTATSRNV QAMNDLHASQ RRDEDAIFSE EEFCTPAGAS SLESNLQNEV YADRDVDVMC
     GCLDGFAECS VTFNEEECEV LSCSDGRWNC LDPDASSVSV CTIERIITTW LLLDDIAPSL
     FLIQSTTEYT SGVANIHKTS ALISVIEEEE PECLMFNVDR SQKKVTSKML CAKEDGKDSC
     QGDSGGPLLI KGADSSQDLQ IGVVSWGVGC GEDGAYPSVY ARVSSAYDWI RAQVCKGSVD
     PPASFECDES AADDTVRSGH AKQERIVGGE DAKVGRFQYA VGLAYPLFGQ FCGGSLIAPD
     VVLSAAHCMN TADFVVPYNV IIGRHDLEEQ TEGESIAMSD EVKHPNYDLL SLENDFALVF
     LASPTYNYEV VQLNQDDNIP QSGDPVTAIG YGDTDPDVTV MTPSMILQEV EKKALSNEEC
     NEIPEWENFN GQACNSCEVC EQDGSSVKVK ADWWVMFRRP SSPPFPAESI CSSEDAFALK
     MALSEVMPDG DIANIDCNCQ SDTGLVLCDV EFLEEICVDG FPLCWKSSQV QLWNVATFDL
     KSVTYKSEYT QGALFVTSDS FTIENPQTND ATCSGYYVNG EQCSSCTLCS GVEEISTVGD
     C
//