ID K0RPB3_THAOC Unreviewed; 650 AA.
AC K0RPB3;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Propionyl-CoA carboxylase {ECO:0008006|Google:ProtNLM};
GN ORFNames=THAOC_32620 {ECO:0000313|EMBL:EJK48572.1};
OS Thalassiosira oceanica (Marine diatom).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Coscinodiscophyceae; Thalassiosirophycidae; Thalassiosirales;
OC Thalassiosiraceae; Thalassiosira.
OX NCBI_TaxID=159749 {ECO:0000313|EMBL:EJK48572.1, ECO:0000313|Proteomes:UP000266841};
RN [1] {ECO:0000313|EMBL:EJK48572.1, ECO:0000313|Proteomes:UP000266841}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1005 {ECO:0000313|EMBL:EJK48572.1,
RC ECO:0000313|Proteomes:UP000266841};
RX PubMed=22835381; DOI=10.1186/gb-2012-13-7-r66;
RA Lommer M., Specht M., Roy A.S., Kraemer L., Andreson R., Gutowska M.A.,
RA Wolf J., Bergner S.V., Schilhabel M.B., Klostermeier U.C., Beiko R.G.,
RA Rosenstiel P., Hippler M., Laroche J.;
RT "Genome and low-iron response of an oceanic diatom adapted to chronic iron
RT limitation.";
RL Genome Biol. 13:R66-R66(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJK48572.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AGNL01045697; EJK48572.1; -; Genomic_DNA.
DR AlphaFoldDB; K0RPB3; -.
DR EnsemblProtists; EJK48572; EJK48572; THAOC_32620.
DR eggNOG; KOG0238; Eukaryota.
DR Proteomes; UP000266841; Unassembled WGS sequence.
DR CDD; cd06850; biotinyl_domain; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR001882; Biotin_BS.
DR InterPro; IPR011764; Biotin_carboxylation_dom.
DR InterPro; IPR005482; Biotin_COase_C.
DR InterPro; IPR000089; Biotin_lipoyl.
DR InterPro; IPR011054; Rudment_hybrid_motif.
DR InterPro; IPR011053; Single_hybrid_motif.
DR PANTHER; PTHR18866; CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE; 1.
DR PANTHER; PTHR18866:SF33; METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF02785; Biotin_carb_C; 1.
DR Pfam; PF00364; Biotin_lipoyl; 1.
DR SMART; SM00878; Biotin_carb_C; 1.
DR SUPFAM; SSF51246; Rudiment single hybrid motif; 1.
DR SUPFAM; SSF51230; Single hybrid motif; 1.
DR PROSITE; PS50979; BC; 1.
DR PROSITE; PS00188; BIOTIN; 1.
DR PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
PE 4: Predicted;
KW Biotin {ECO:0000256|ARBA:ARBA00023267};
KW Reference proteome {ECO:0000313|Proteomes:UP000266841}.
FT DOMAIN 1..401
FT /note="Biotin carboxylation"
FT /evidence="ECO:0000259|PROSITE:PS50979"
FT DOMAIN 558..638
FT /note="Lipoyl-binding"
FT /evidence="ECO:0000259|PROSITE:PS50968"
FT REGION 1..221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 275..316
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..23
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..60
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..148
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..171
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 197..214
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 280..316
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 650 AA; 71346 MW; 130F19148DBA7643 CRC64;
MHVNRRPKNE SNRTRRRAGR RGIPPRPGRG PVLLRGRPPP RREVRRGPPT HRDTGPLRPG
SRHGRPRRPM LRRAGVQHTE EEPEGPRGES QPDARQGDSE GDDKAGQEPG EGGGLRERGD
RRVLGGRGAE LLLPRDEHEA PGRAPGHRDD KRRRLRLREL RRPRPRHARG GVRTGRAPGV
PRHGRVRPGP RRAGRGGGSE RQVHGTRRRG EGLRRGSLPG IPAEHRTACE VRRAAGRAGN
RGRGGIGDVL VSFSSPSKRD FGEIKVTDAS FPFLDANQKI QSDEEGKNEE RRDGGGELCD
GDYDNDNPRD EGSKKSACHI RVDTGVAPGY VVSPHYDPIL SKIISYSETS RAESIEGLGR
AIDRYKLRGV MHNVPFIRDV LRNADFVRGE TPTGFIDAHY PDGFSGGRLT ATEMKEYAAI
AALVHERRRA ETGGPPLPMD AGEAGGGGPQ SAERIVCVNG MFGDAYRVRT EVGPGGFTTC
SVARLGDDED VETVVKSDRG DVNYHPRDDF ACVPVSSDDS RVVQVHGEDE MGQLKLTMFG
LDADFLVTTP GEYELTRHMK EPVPVDLGDY VMSPMPGTLV SFAVKEGDVV EMGQELCVVE
AMKMQNIIRS HKAGARVSKL HGEVGASLRA DEILLEFEKE TTEEEEEEVA
//
