ID   K0SMA3_THAOC            Unreviewed;       517 AA.
AC   K0SMA3;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=PA domain-containing protein {ECO:0000259|Pfam:PF02225};
GN   ORFNames=THAOC_12589 {ECO:0000313|EMBL:EJK66490.1};
OS   Thalassiosira oceanica (Marine diatom).
OC   Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC   Coscinodiscophyceae; Thalassiosirophycidae; Thalassiosirales;
OC   Thalassiosiraceae; Thalassiosira.
OX   NCBI_TaxID=159749 {ECO:0000313|EMBL:EJK66490.1, ECO:0000313|Proteomes:UP000266841};
RN   [1] {ECO:0000313|EMBL:EJK66490.1, ECO:0000313|Proteomes:UP000266841}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCMP1005 {ECO:0000313|EMBL:EJK66490.1,
RC   ECO:0000313|Proteomes:UP000266841};
RX   PubMed=22835381; DOI=10.1186/gb-2012-13-7-r66;
RA   Lommer M., Specht M., Roy A.S., Kraemer L., Andreson R., Gutowska M.A.,
RA   Wolf J., Bergner S.V., Schilhabel M.B., Klostermeier U.C., Beiko R.G.,
RA   Rosenstiel P., Hippler M., Laroche J.;
RT   "Genome and low-iron response of an oceanic diatom adapted to chronic iron
RT   limitation.";
RL   Genome Biol. 13:R66-R66(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJK66490.1}.
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DR   EMBL; AGNL01014904; EJK66490.1; -; Genomic_DNA.
DR   AlphaFoldDB; K0SMA3; -.
DR   EnsemblProtists; EJK66490; EJK66490; THAOC_12589.
DR   eggNOG; ENOG502QSX2; Eukaryota.
DR   OMA; INGARYS; -.
DR   Proteomes; UP000266841; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.50.30.30; -; 1.
DR   InterPro; IPR046450; PA_dom_sf.
DR   InterPro; IPR003137; PA_domain.
DR   PANTHER; PTHR22702; PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR22702:SF1; PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF02225; PA; 1.
DR   SUPFAM; SSF52025; PA domain; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000266841};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..517
FT                   /note="PA domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5030173078"
FT   TRANSMEM        448..470
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          70..182
FT                   /note="PA"
FT                   /evidence="ECO:0000259|Pfam:PF02225"
SQ   SEQUENCE   517 AA;  56815 MW;  8BD3C65359970ABF CRC64;
     MTALNSILAS TLLLQAVSVV RGDSADAVSS RLQVHVPHTL FRPDGYDHRE ALFGVPPYGG
     SIAQSIFYAD SDLCDPTVDT RKGYPIRSKD SKGKMEPWPS PYILMVDRGG CSFVQKVRNA
     QRSGAAGVVI ADNTCLCSDT NCVSANGEDV CQPAEPIMAD DGSGGDISIP SFLMFKTDAD
     QIKAEVRANH MVQVEMQWAL PQPDDRVEYD LWTTPSDPVS KEFQKNFKSV SQALGDRAYF
     TPHMYVYDGV KSNCQGLDGE NMCFNLCTNN GRYCATDPDN DLDHGISGAD VVKESLRRIC
     IWKHYGEQDG IGKEWWDYTS EFIERCDNPD YFANDDCVKD VYKHSGIKGD IVDRCIRDSG
     GLDQDNTNTF LELEMSAQVK RGVVILPTAF VNTVALRGGL SVDTVFTAIC NGYLEGTEPS
     ICKQCDGCSD FETCIQKKKC NGRGGGGVSM HTFMGSILLI AALFGGAAFW HYRKTREDMR
     DQVRGILAEY MPLEGDDGHI GSPMDFARKG GTESLMT
//