ID K0V7A1_MYCVA Unreviewed; 488 AA.
AC K0V7A1;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Glutamate synthase subunit beta {ECO:0000313|EMBL:EJZ10708.1};
DE EC=1.4.1.13 {ECO:0000313|EMBL:EJZ10708.1};
GN Name=gltD {ECO:0000313|EMBL:EJZ10708.1};
GN ORFNames=MVAC_08314 {ECO:0000313|EMBL:EJZ10708.1};
OS Mycolicibacterium vaccae ATCC 25954.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=1194972 {ECO:0000313|EMBL:EJZ10708.1, ECO:0000313|Proteomes:UP000006072};
RN [1] {ECO:0000313|EMBL:EJZ10708.1, ECO:0000313|Proteomes:UP000006072}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25954 {ECO:0000313|EMBL:EJZ10708.1,
RC ECO:0000313|Proteomes:UP000006072};
RX PubMed=23105074; DOI=10.1128/JB.01462-12;
RA Ho Y.S., Adroub S.A., Abadi M., Al Alwan B., Alkhateeb R., Gao G.,
RA Ragab A., Ali S., van Soolingen D., Bitter W., Pain A., Abdallah A.M.;
RT "Complete Genome Sequence of Mycobacterium vaccae Type Strain ATCC 25954.";
RL J. Bacteriol. 194:6339-6340(2012).
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJZ10708.1}.
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DR EMBL; ALQA01000013; EJZ10708.1; -; Genomic_DNA.
DR RefSeq; WP_003931339.1; NZ_JH814693.1.
DR AlphaFoldDB; K0V7A1; -.
DR PATRIC; fig|1194972.3.peg.1674; -.
DR eggNOG; COG0493; Bacteria.
DR HOGENOM; CLU_000422_3_1_11; -.
DR Proteomes; UP000006072; Unassembled WGS sequence.
DR GO; GO:0004355; F:glutamate synthase (NADPH) activity; IEA:UniProtKB-EC.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0006537; P:glutamate biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR028261; DPD_II.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR006005; Glut_synth_ssu1.
DR InterPro; IPR009051; Helical_ferredxn.
DR NCBIfam; TIGR01317; GOGAT_sm_gam; 1.
DR PANTHER; PTHR43100; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR PANTHER; PTHR43100:SF1; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR Pfam; PF14691; Fer4_20; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PRINTS; PR00419; ADXRDTASE.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Glutamate biosynthesis {ECO:0000256|ARBA:ARBA00023164};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EJZ10708.1}.
FT DOMAIN 25..132
FT /note="Dihydroprymidine dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF14691"
FT DOMAIN 146..459
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
SQ SEQUENCE 488 AA; 53561 MW; 7F90C29FB8EA3726 CRC64;
MADPRGFLKF THRETPKRRP VDLRLKDWDE VYEEFSQDTL KEQASRCMDC GIPFCHNGCP
LGNLIPEWND LVRTNRWRDA IERLHATNNF PEFTGRLCPA PCEGSCVLGI NQDPVTIKQV
EVEIIDNAFR EGWVVPLPPT KLTGKTVAVV GSGPAGLAAA QQLTRAGHKV TVFERDDRIG
GLLRYGIPEF KMEKRHIDRR LDQMRAEGTE FRTGVNVGVD ITAAQLRSEF DAVVLAGGAT
ARRDLPIPGR ELDGIHQAME YLPWANRVQL GDPVIDAEGQ PPITAKGKKV IIIGGGDTGA
DCLGTSHRQG AVSVHQFEIM PRPPETRADS TPWPTYPLMY RVTSAHEEGG ERVYSVNTEE
FLGENGRVTG LRGHEVVMKD GKFEKVDGSD FEMEADLVLL AMGFTGPERE GLLTDLQVEM
SDRGNVGRDD AFATSVPGVY VAGDMGRGQS LIVWAIAEGR AAAAAVDRYL MGNTALPAPI
KPTAVPQR
//
