ID K0XFQ7_9FIRM Unreviewed; 435 AA.
AC K0XFQ7;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Alpha-L-fucosidase {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF1135_01567 {ECO:0000313|EMBL:EJZ69918.1};
OS Lachnoanaerobaculum sp. OBRC5-5.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Lachnoanaerobaculum.
OX NCBI_TaxID=936595 {ECO:0000313|EMBL:EJZ69918.1, ECO:0000313|Proteomes:UP000006070};
RN [1] {ECO:0000313|EMBL:EJZ69918.1, ECO:0000313|Proteomes:UP000006070}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OBRC5-5 {ECO:0000313|EMBL:EJZ69918.1,
RC ECO:0000313|Proteomes:UP000006070};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Sizova M., Hazen A.,
RA Epstein S., Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M.,
RA Haas B., Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.M.,
RA Chapman S.B., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Larimer J., McCowen C., Montmayeur A., Murphy C., Neiman D.,
RA Pearson M., Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Clostridiales bacterium OBRC5-5.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-
CC 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the
CC carbohydrate moieties of glycoproteins.
CC {ECO:0000256|ARBA:ARBA00004071}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJZ69918.1}.
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DR EMBL; ALOA01000008; EJZ69918.1; -; Genomic_DNA.
DR RefSeq; WP_007593953.1; NZ_JH815185.1.
DR AlphaFoldDB; K0XFQ7; -.
DR STRING; 936595.HMPREF1135_01567; -.
DR PATRIC; fig|1125778.3.peg.1577; -.
DR HOGENOM; CLU_002934_0_2_9; -.
DR Proteomes; UP000006070; Unassembled WGS sequence.
DR GO; GO:0004560; F:alpha-L-fucosidase activity; IEA:InterPro.
DR GO; GO:0006004; P:fucose metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR016286; FUC_metazoa-typ.
DR InterPro; IPR000933; Glyco_hydro_29.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR10030; ALPHA-L-FUCOSIDASE; 1.
DR PANTHER; PTHR10030:SF46; ALPHA-L-FUCOSIDASE-RELATED; 1.
DR Pfam; PF01120; Alpha_L_fucos; 1.
DR PIRSF; PIRSF001092; Alpha-L-fucosidase; 1.
DR PRINTS; PR00741; GLHYDRLASE29.
DR SMART; SM00812; Alpha_L_fucos; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT SITE 265
FT /note="May be important for catalysis"
FT /evidence="ECO:0000256|PIRSR:PIRSR001092-1"
SQ SEQUENCE 435 AA; 50381 MW; 06A4C831855169B8 CRC64;
MNKEIRERTK WFMDARFGMF IHWGLYSIPA CGEWVMSQKE MTVEEYRTYF EQFDPVDYDP
KKWVKLAKEA GMKYAVLTAK HHDGFCLFDS KLTDYKATNT KAGRDLVREF VDACREEGLR
VGLYFSIIDW HHPDFPKYRD RQHPMRNNKA YENEEIDFER YLEYMHGQVK ELVTGYGKLD
LLWFDFSYDD MTGEKWKATE LIKMVRSYQP DVIIDNRLEG SGESHGSIAT EHPLIYSGDF
ASPEQIIPPN GVCDEKGEPI PWELCATMNN HWGYCKFDHQ YKTPQMLVRK LVECVSKGGN
MILNVGPDAN GNIPQESINI LTDLGKWMSK NKESIYGCGI SELEKPDWGR YTQKGNTIYA
HVYETPLGAL PLYGIVPDKL DKITYLADGS EVRRGEAWNT ALYPDIAFVS FGEDPVFTYP
LPDDKDTVLK IELKE
//
